Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G000891`

染色体: Chr02 坐标: 15334998-15339992 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G000891`
名称	SmilChr02G000891
描述	isocitrate dehydrogenase [NADP]-like
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	15334998 - 15339992 / `+`

ID 对照

NCBI Gene ID	`LOC131011338`
GeneID	`131011338`
locus_tag	`-`
NCBI Name	`LOC131011338`
原始查询	`SmilChr02G000891`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	isocitrate dehydrogenase [NADP]-like
产物	isocitrate dehydrogenase [NADP]-like
Arabidopsis	`AT1G65930` (cICDH) cytosolic NADP+-dependent isocitrate dehydrogenase [Source:NCBI gene (formerly Entrezgene);Acc:842905] identity=83.9; qcov=0.938; evalue=0; confidence=high
Rice	`Os05g0573200` - identity=85.2; qcov=0.94; evalue=0; confidence=high
GO	GO:0000287 (magnesium ion binding); GO:0004450 (isocitrate dehydrogenase (NADP+) activity); GO:0005739 (mitochondrion); GO:0006102 (isocitrate metabolic process); GO:0051287 (NAD binding)
KEGG	smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil00480 (Glutathione metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage)); smil04146 (Peroxisome - Salvia miltiorrhiza (redroot sage))
Pfam	PF00180 (Iso_dh)
InterPro	-
eggNOG	-
NR	GeneID:131011338

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057795106.1`
2	Peroxisome	过氧化物酶体	0.80000	`XP_057795107.1`
3	Cytosol	细胞质基质	0.20000	`XP_057795106.1`
4	Nucleus	细胞核	0.00000	`XP_057795106.1`
5	Chromosome	染色体	0.00000	`XP_057795106.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:15336075`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	C39,C68,C74,D3
`Chr2:15336114`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A24
`Chr2:15337037`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr2:15338323`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr2:15338331`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C43
`Chr2:15338372`	`A`	`AAT`	2bp_insertion	frameshift_variant	7	B115,B126,B17,B58,B65,B70,C33
`Chr2:15338381`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A15,B47,C40,C46,C84
`Chr2:15338696`	`TA`	`T`	1bp_deletion	frameshift_variant	1	C84
`Chr2:15338696`	`TA`	`T`	1bp_deletion	CDS_variant	1	C84
`Chr2:15339459`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B113,B129,B138,C36,C62
`Chr2:15339706`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B122,C15,C49

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057795106.1

416 aa

208

416

Iso_dh

PF00180 Iso_dh 7-402 aa

XP_057795107.1

352 aa

176

352

Iso_dh

PF00180 Iso_dh 11-338 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057795106.1`	Pfam	`PF00180`	Iso_dh	Domain	7	402	9.3e-77	259.3	Isocitrate/isopropylmalate dehydrogenase
`XP_057795107.1`	Pfam	`PF00180`	Iso_dh	Domain	11	338	5.3e-60	204.2	Isocitrate/isopropylmalate dehydrogenase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057939123.1
ATCTAATGATGGACCCACCGCAGCTTAACCACGTTTTTCTTCTGTAATGAAAAAAAAAAAAAAAAAGATCAAGAAAAAAAAATGAAAGTCGTGCAAAACAAGAAAATCATTTATATTTATATAATCGGTGCCTGCATAGTTGTGCTCTGATTATACTCAATTCAGCAAAGCCTTTTAAGTAGATTACCGAGGAAGAATTTCGCGCCAGCTGACGATGAGTTTCGACAAGATTAAAGTCCACAACCCCATCGTAGAGATGG...

XM_057939124.1
GTGCAGGTGATGAAATGACTCGAGTGATATGGAGATATATCAAAGAAAAGCTCATACATCCTTTCCTGGAGCTAGACATAAAGTACTTTGACCTTGGTATTCATCATCGTGATGCTACAAACGACAAAGTTACAGTTGAAAGTGCAGAAGCCACCCTTAAATGAAGCCCGTGTTAAAGAGTTCAACTTGAAACAGATGTGGAGAAGTCCAAATGGGACCATTCGGAACATCTTGAACGGGACAGTATTTAGAGAACCAAT...

CDS

2 records

下载 CDS FASTA

LOC131011338
ATGAGTTTCGACAAGATTAAAGTCCACAACCCCATCGTAGAGATGGACGGTGATGAAATGACTCGAGTGATATGGAGATATATCAAAGAAAAGCTCATACATCCTTTCCTGGAGCTAGACATAAAGTACTTTGACCTTGGTATTCATCATCGTGATGCTACAAACGACAAAGTTACAGTTGAAAGTGCAGAAGCCACCCTTAAGTACAATGTGGCAATTAAATGTGCAACCATTACTCCAGATGAAGCCCGTGTTAAAGA...

LOC131011338
ATGCTACAAACGACAAAGTTACAGTTGAAAGTGCAGAAGCCACCCTTAAATGAAGCCCGTGTTAAAGAGTTCAACTTGAAACAGATGTGGAGAAGTCCAAATGGGACCATTCGGAACATCTTGAACGGGACAGTATTTAGAGAACCAATCATATGCAAGAACGTCCCTCGGCTTGTGTCAGGTTGGACCAAGCCCATATGCATTGGGAGACATGCCTATGGGGATCAGTATCGAGCTACTGATGTAGTAATTGAAGGAGC...

Protein

2 records

下载 Protein FASTA

XP_057795106.1
MSFDKIKVHNPIVEMDGDEMTRVIWRYIKEKLIHPFLELDIKYFDLGIHHRDATNDKVTVESAEATLKYNVAIKCATITPDEARVKEFNLKQMWRSPNGTIRNILNGTVFREPIICKNVPRLVSGWTKPICIGRHAYGDQYRATDVVIEGAGKLKMVFVPDRGTKSVELEVFNFTGPGGVALSMYNTDESIRAFAEASMNTAYQKLWPLYLSTKNTILKNYDGRFKDIFQEIYEREWRSKFEAAGIWYEHRLIDDMVAYA...

XP_057795107.1
MLQTTKLQLKVQKPPLNEARVKEFNLKQMWRSPNGTIRNILNGTVFREPIICKNVPRLVSGWTKPICIGRHAYGDQYRATDVVIEGAGKLKMVFVPDRGTKSVELEVFNFTGPGGVALSMYNTDESIRAFAEASMNTAYQKLWPLYLSTKNTILKNYDGRFKDIFQEIYEREWRSKFEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYRVHQKG...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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