Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G000911`

染色体: Chr02 坐标: 15751612-15756565 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G000911`
名称	SmilChr02G000911
描述	isocitrate dehydrogenase [NADP]-like
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	15751612 - 15756565 / `-`

ID 对照

NCBI Gene ID	`LOC131011351`
GeneID	`131011351`
locus_tag	`-`
NCBI Name	`LOC131011351`
原始查询	`SmilChr02G000911`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	isocitrate dehydrogenase [NADP]-like
产物	isocitrate dehydrogenase [NADP]-like
Arabidopsis	`AT1G65930` (cICDH) cytosolic NADP+-dependent isocitrate dehydrogenase [Source:NCBI gene (formerly Entrezgene);Acc:842905] identity=83.9; qcov=0.938; evalue=0; confidence=high
Rice	`Os05g0573200` - identity=85.2; qcov=0.94; evalue=0; confidence=high
GO	GO:0000287 (magnesium ion binding); GO:0004450 (isocitrate dehydrogenase (NADP+) activity); GO:0005739 (mitochondrion); GO:0006102 (isocitrate metabolic process); GO:0051287 (NAD binding)
KEGG	smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil00480 (Glutathione metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage)); smil04146 (Peroxisome - Salvia miltiorrhiza (redroot sage))
Pfam	PF00180 (Iso_dh)
InterPro	-
eggNOG	-
NR	GeneID:131011351

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057795123.1`
2	Peroxisome	过氧化物酶体	0.80000	`XP_057795125.1`
3	Cytosol	细胞质基质	0.20000	`XP_057795123.1`
4	Nucleus	细胞核	0.00000	`XP_057795125.1`
5	Chromosome	染色体	0.00000	`XP_057795125.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:15752091`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B111
`Chr2:15752387`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B23,B4,C27,C44
`Chr2:15752464`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B98,C62
`Chr2:15753033`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr2:15753236`	`G`	`GTA`	2bp_insertion	frameshift_variant	4	B115,B30,B58,B65
`Chr2:15753236`	`G`	`GTA`	2bp_insertion	CDS_variant	4	B115,B30,B58,B65
`Chr2:15753281`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B106,B136,B55,C28,C43
`Chr2:15753308`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B41
`Chr2:15754383`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B7
`Chr2:15754548`	`G`	`A`	EMS_canonical_SNV	stop_gained	1	B80
`Chr2:15754548`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B80
`Chr2:15754575`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057795123.1

416 aa

208

416

Iso_dh

PF00180 Iso_dh 7-402 aa

XP_057795124.1

397 aa

198

397

Iso_dh

PF00180 Iso_dh 2-383 aa

XP_057795125.1

352 aa

176

352

Iso_dh

PF00180 Iso_dh 11-338 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057795123.1`	Pfam	`PF00180`	Iso_dh	Domain	7	402	1.2e-76	258.9	Isocitrate/isopropylmalate dehydrogenase
`XP_057795124.1`	Pfam	`PF00180`	Iso_dh	Domain	2	383	2.1e-72	245.0	Isocitrate/isopropylmalate dehydrogenase
`XP_057795125.1`	Pfam	`PF00180`	Iso_dh	Domain	11	338	7e-60	203.8	Isocitrate/isopropylmalate dehydrogenase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057939140.1
TTTCTTCTGTAATGCAAAAAAAAAAAAAGATTAAGAAAAAAAAATGAAAGTCGTCCAAAACAAGAAAATCATTTATATTTATATAATCGGTGCCTGCATAGTTGTGCTCTGATTATACTCAATTCAGCAAAGCCTTTTAAGTAGATTACCGAGGAAGAATTTCGCGCCAGCTGACGATGAGTTTCGACAAGATTAAAGTCCACAACCCCATCGTAGAGATGGACGGTGATGAAATGACTCGAGTGATATGGAGATATATC...

XM_057939142.1
TTTCCTCTCTGAGACTTGATTGCTAGAGACAATTCGTTGCTAATATTTGTTTATTACGTTTAGATAGGTTTTACTGAGTTTTATTTTGTGGTAGGCGCTATTGCTGTTGAAATCGAGACTGCAAGCAGTCTCTTGGTTGATCCCCGTTTAGATGTTTCCTCACAATCTTTATTAGTTGGGAGCGGTGGCATTTTGTAATAATAGAGGCATTTTCCATACATTTTCACAATGAGACGAAGTTTTCTTTCCTTTAATGGTGG...

CDS

3 records

下载 CDS FASTA

LOC131011351
ATGAGTTTCGACAAGATTAAAGTCCACAACCCCATCGTAGAGATGGACGGTGATGAAATGACTCGAGTGATATGGAGATATATCAAAGAAAAGCTCATACATCCTTTCCTGGAGCTAGACATAAAGTACTTTGACCTTGGTATTCATCATCGTGATGCTACAAACGACAAAGTTACAGTTGAAAGTGCAGAAGCCACCCTTAAGTACAATGTGGCAATTAAATGTGCAACCATTACTCCAGATGAAGCCCGTGTTAAAGA...

LOC131011351
ATGACTCGAGTGATATGGAGATATATCAAAGAAAAGCTCATACATCCTTTCCTGGAGCTAGACATAAAGTACTTTGACCTTGGTATTCATCATCGTGATGCTACAAACGACAAAGTTACAGTTGAAAGTGCAGAAGCCACCCTTAAGTACAATGTGGCAATTAAATGTGCAACCATTACTCCAGATGAAGCCCGTGTTAAAGAGTTCAACTTGAAACAGATGTGGAGAAGTCCAAATGGGACCATTCGGAACATCTTGAA...

Protein

3 records

下载 Protein FASTA

XP_057795123.1
MSFDKIKVHNPIVEMDGDEMTRVIWRYIKEKLIHPFLELDIKYFDLGIHHRDATNDKVTVESAEATLKYNVAIKCATITPDEARVKEFNLKQMWRSPNGTIRNILNGTVFREPIICKNVPRLVSGWTKPICIGRHAYGDQYRATDVVIEGAGKLKMVFVPDRGTKSVELEVFNFTGPGGVALSMYNTDESIRAFAEASMNTAYQKLWPLYLSTKNTILKNYDGRFKDIFQDVYEREWRSKFEAAGIWYEHRLIDDMVAYA...

XP_057795124.1
MTRVIWRYIKEKLIHPFLELDIKYFDLGIHHRDATNDKVTVESAEATLKYNVAIKCATITPDEARVKEFNLKQMWRSPNGTIRNILNGTVFREPIICKNVPRLVSGWTKPICIGRHAYGDQYRATDVVIEGAGKLKMVFVPDRGTKSVELEVFNFTGPGGVALSMYNTDESIRAFAEASMNTAYQKLWPLYLSTKNTILKNYDGRFKDIFQDVYEREWRSKFEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQ...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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