Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G001341`

染色体: Chr02 坐标: 24989018-24994857 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G001341`
名称	SmilChr02G001341
描述	mRNA cap guanine-N7 methyltransferase 1
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	24989018 - 24994857 / `+`

ID 对照

NCBI Gene ID	`LOC131007817`
GeneID	`131007817`
locus_tag	`-`
NCBI Name	`LOC131007817`
原始查询	`SmilChr02G001341`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	mRNA cap guanine-N7 methyltransferase 1
产物	mRNA cap guanine-N7 methyltransferase 1
Arabidopsis	`AT3G20650` (AT3G20650) mRNA capping enzyme family protein [Source:NCBI gene (formerly Entrezgene);Acc:821612] identity=82.7; qcov=0.992; evalue=0; confidence=high
Rice	`Os08g0180000` - identity=71.5; qcov=0.987; evalue=0; confidence=high
GO	GO:0004482 (mRNA 5'-cap (guanine-N7-)-methyltransferase activity); GO:0005634 (nucleus); GO:0005845 (GO:0005845); GO:0006370 (7-methylguanosine mRNA capping)
KEGG	smil03015 (mRNA surveillance pathway - Salvia miltiorrhiza (redroot sage))
Pfam	PF03291 (mRNA_G-N7_MeTrfase); PF08241 (Methyltransf_11); PF08242 (Methyltransf_12); PF13649 (Methyltransf_25); PF13847 (Methyltransf_31)
InterPro	-
eggNOG	-
NR	GeneID:131007817

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057790717.1`
2	Cytosol	细胞质基质	1.00000	`XP_057790717.1`
3	Cytoplasm	细胞质	0.80000	`XP_057790717.1`
4	Nucleoplasm	核质	0.40000	`XP_057790717.1`
5	Chromosome	染色体	0.00000	`XP_057790717.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:24991118`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B55,B56,B96
`Chr2:24991196`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C47
`Chr2:24994354`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B42,B43,C50
`Chr2:24994494`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr2:24994565`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057790717.1

373 aa

186

373

mRNA_G-N7_MeTrfase

Methyltransf_31

Methyltransf_25

Methyltransf_12

Methyltransf_11

PF03291 mRNA_G-N7_MeTrfase 33-342 aa PF13847 Methyltransf_31 84-209 aa PF13649 Methyltransf_25 89-201 aa PF08242 Methyltransf_12 90-203 aa PF08241 Methyltransf_11 90-204 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057790717.1`	Pfam	`PF03291`	mRNA_G-N7_MeTrfase	Domain	33	342	1.5e-128	429.1	mRNA (guanine-N(7))-methyltransferase domain
`XP_057790717.1`	Pfam	`PF13847`	Methyltransf_31	Domain	84	209	6.3e-10	39.7	Methyltransferase domain
`XP_057790717.1`	Pfam	`PF13649`	Methyltransf_25	Domain	89	201	1.1e-10	42.8	Methyltransferase domain
`XP_057790717.1`	Pfam	`PF08242`	Methyltransf_12	Domain	90	203	1e-09	39.7	Methyltransferase domain
`XP_057790717.1`	Pfam	`PF08241`	Methyltransf_11	Domain	90	204	5.5e-09	37.3	Methyltransferase domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057934734.1
ATATAGCATTGAAGGCGGAAAAAAAGTAAGAAATTGTGAAGAAACAAGTTAAAATATTGTTACACAGCTCTACTTCTGGAATTTTTGTTTAACCCAAACCTCTATTACTTTCTTTATCCATCCATTCATTCATTCATTCCGCAGAATAACACAAAAGTAATACTAATTTGTAACCTTGAACCTTTTTATCGGTTTGCTTCTTCCTCTCCTTCTTCAAACATTTGATTAAAACCCTTCTTCAATTCATCGCTGCCGGATTT...

CDS

1 records

下载 CDS FASTA

LOC131007817
ATGAAGCGAGGCTATCAAGAATCTTCATCATCGAGTTCTTATGTACCCCCTCAGTCCAAAGTAAAGTATAATCCTGAAGGTGATGTACAATTTCTAGAGGATGAGAATACTAAGATATTTGCAAGGAAAGTGGCTGATCATTACAGTGCAAGGACGAATCAGACGCTCGAAGAACGAGAAGCAAGCCCTATAATTCACCTGAAGAAACTCAATAATTGGATAAAGAGTGTGTTGATTCAGCTATATGCAAAAAAAGGAGA...

Protein

1 records

下载 Protein FASTA

XP_057790717.1
MKRGYQESSSSSSYVPPQSKVKYNPEGDVQFLEDENTKIFARKVADHYSARTNQTLEEREASPIIHLKKLNNWIKSVLIQLYAKKGDAVLDLACGKGGDLIKWDKAKIGYYVGIDIADGSIEDCRTRYNGDADHHQRRKKFSFPARLICGDCFEAQLDKVLAEDAPFDICSCQFAMHYSWSTEARARRALANVSALLRPGGIFIGTMPDANVIVKKLREAEGLQFGNSVYWIRFDKEFDDKKFKSSSPFGIKYKFHLEDA...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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