Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G002493`

染色体: Chr02 坐标: 43367254-43370939 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G002493`
名称	SmilChr02G002493
描述	LRR receptor-like serine/threonine-protein kinase FLS2
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	43367254 - 43370939 / `-`

ID 对照

NCBI Gene ID	`LOC131013589`
GeneID	`131013589`
locus_tag	`-`
NCBI Name	`LOC131013589`
原始查询	`SmilChr02G002493`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	LRR receptor-like serine/threonine-protein kinase FLS2
产物	LRR receptor-like serine/threonine-protein kinase FLS2
Arabidopsis	`AT5G46330` (FLS2) Leucine-rich receptor-like protein kinase family protein [Source:NCBI gene (formerly Entrezgene);Acc:834676] identity=51.8; qcov=1.01; evalue=0; confidence=high
Rice	`Os04g0618700` (Os-FLS2) - identity=47.2; qcov=1.02; evalue=0; confidence=high
GO	GO:0004672 (protein kinase activity); GO:0005515 (protein binding); GO:0005524 (ATP binding); GO:0005886 (plasma membrane); GO:0006468 (protein phosphorylation)
KEGG	smil04016 (MAPK signaling pathway - plant - Salvia miltiorrhiza (redroot sage)); smil04626 (Plant-pathogen interaction - Salvia miltiorrhiza (redroot sage))
Pfam	PF00069 (Pkinase); PF00560 (LRR_1); PF07714 (PK_Tyr_Ser-Thr); PF08263 (LRRNT_2); PF13855 (LRR_8)
InterPro	-
eggNOG	-
NR	GeneID:131013589

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057797699.1`
2	Nucleus	细胞核	0.00000	`XP_057797699.1`
3	Chromosome	染色体	0.00000	`XP_057797699.1`
4	Centromere	着丝粒	0.00000	`XP_057797699.1`
5	Chromatin	染色质	0.00000	`XP_057797699.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:43367460`	`G`	`GT`	1bp_insertion	frameshift_variant	4	B11,B16,B74,C40
`Chr2:43367460`	`G`	`GT`	1bp_insertion	CDS_variant	4	B11,B16,B74,C40
`Chr2:43367573`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B126
`Chr2:43367638`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A4,B63,B81,B83
`Chr2:43367863`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A15,B47,C56,C65
`Chr2:43367884`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	C44,C55,C7
`Chr2:43367885`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B30,B51,C34,C37
`Chr2:43368083`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B1
`Chr2:43368342`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B2,B40
`Chr2:43368410`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B40
`Chr2:43368607`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A4,B140,B63,B81,B83
`Chr2:43368751`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B68

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057797699.1

1139 aa

570

1139

LRRNT_2

LRR_1

LRR_8

LRR_1

LRR_8

LRR_1

Pkinase

PK_Tyr_Ser-Thr

PF08263 LRRNT_2 23-63 aa PF00560 LRR_1 140-162 aa PF00560 LRR_1 332-354 aa PF00560 LRR_1 573-594 aa PF00560 LRR_1 596-613 aa PF00560 LRR_1 647-668 aa PF13855 LRR_8 648-706 aa PF00560 LRR_1 670-687 aa PF13855 LRR_8 695-754 aa PF00560 LRR_1 696-717 aa PF00560 LRR_1 719-739 aa PF00069 Pkinase 852-1130 aa PF07714 PK_Tyr_Ser-Thr 854-1131 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057797699.1`	Pfam	`PF08263`	LRRNT_2	Family	23	63	2.5e-13	50.7	Leucine rich repeat N-terminal domain
`XP_057797699.1`	Pfam	`PF00560`	LRR_1	Repeat	140	162	4.7e-53	166.3	Leucine Rich Repeat
`XP_057797699.1`	Pfam	`PF00560`	LRR_1	Repeat	332	354	4.7e-53	166.3	Leucine Rich Repeat
`XP_057797699.1`	Pfam	`PF00560`	LRR_1	Repeat	573	594	4.7e-53	166.3	Leucine Rich Repeat
`XP_057797699.1`	Pfam	`PF00560`	LRR_1	Repeat	596	613	4.7e-53	166.3	Leucine Rich Repeat
`XP_057797699.1`	Pfam	`PF00560`	LRR_1	Repeat	647	668	4.7e-53	166.3	Leucine Rich Repeat
`XP_057797699.1`	Pfam	`PF13855`	LRR_8	Repeat	648	706	1.3e-48	163.2	Leucine rich repeat
`XP_057797699.1`	Pfam	`PF00560`	LRR_1	Repeat	670	687	4.7e-53	166.3	Leucine Rich Repeat
`XP_057797699.1`	Pfam	`PF13855`	LRR_8	Repeat	695	754	1.3e-48	163.2	Leucine rich repeat
`XP_057797699.1`	Pfam	`PF00560`	LRR_1	Repeat	696	717	4.7e-53	166.3	Leucine Rich Repeat
`XP_057797699.1`	Pfam	`PF00560`	LRR_1	Repeat	719	739	4.7e-53	166.3	Leucine Rich Repeat
`XP_057797699.1`	Pfam	`PF00069`	Pkinase	Domain	852	1130	5.3e-42	144.7	Protein kinase domain
`XP_057797699.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	854	1131	1e-33	117.5	Protein tyrosine and serine/threonine kinase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057941716.1
ACCCAAAAAGGAAAAGTAAAAAGAAAAACAAGAAACCATGTTCTTTCAAGTGATCATACTCATACTACTCTCAACTTTCCTTCTCGGAGCTCTCTCACTACCCCAATCCGAAGTCCAAGCCTTGAAGGCCTTCAAAAACTCGATCACCCACGACCCGACGGGCGCCCTCCTCGACTGGGACGAGGCCGCCCGCCACCACTGCAACTGGACCGGAGTCACATGCGATCCATCTACGCGAAATGTCATCAACATCACCATGG...

CDS

1 records

下载 CDS FASTA

LOC131013589
ATGTTCTTTCAAGTGATCATACTCATACTACTCTCAACTTTCCTTCTCGGAGCTCTCTCACTACCCCAATCCGAAGTCCAAGCCTTGAAGGCCTTCAAAAACTCGATCACCCACGACCCGACGGGCGCCCTCCTCGACTGGGACGAGGCCGCCCGCCACCACTGCAACTGGACCGGAGTCACATGCGATCCATCTACGCGAAATGTCATCAACATCACCATGGTGGACAAGCAGTTGCAAGGCGAGATCTCCCCATTCCT...

Protein

1 records

下载 Protein FASTA

XP_057797699.1
MFFQVIILILLSTFLLGALSLPQSEVQALKAFKNSITHDPTGALLDWDEAARHHCNWTGVTCDPSTRNVINITMVDKQLQGEISPFLGNLSSLEVLDLTLNSFTGQIPTQLVSCTHLTQLILYQNSVSGPIPPELGRLANLQLLDLGDNSLNGSIPDALCNCSELLLLGLNSNNLTGKIPQQIGNLVNLQMFTTYRNNLEGSIPNSIGNLTQMLAFDLSENMLTGKIPQEIGSMSNLEILQLHINLISGEIPPQLGQCTK...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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