Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G002720`

染色体: Chr02 坐标: 47031540-47039140 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G002720`
名称	SmilChr02G002720
描述	putative transcription elongation factor SPT5 homolog 1
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	47031540 - 47039140 / `-`

ID 对照

NCBI Gene ID	`LOC131011755`
GeneID	`131011755`
locus_tag	`-`
NCBI Name	`LOC131011755`
原始查询	`SmilChr02G002720`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	putative transcription elongation factor SPT5 homolog 1
产物	putative transcription elongation factor SPT5 homolog 1
Arabidopsis	`AT4G08350` (GTA2) global transcription factor group A2 [Source:NCBI gene (formerly Entrezgene);Acc:826391] identity=70.7; qcov=1.01; evalue=0; confidence=high
Rice	`Os06g0208300` - identity=69; qcov=0.288; evalue=2.72e-133; confidence=weak
GO	GO:0003729 (mRNA binding); GO:0003735 (structural constituent of ribosome); GO:0005840 (ribosome); GO:0006357 (regulation of transcription by RNA polymerase II); GO:0006368 (transcription elongation by RNA polymerase II); GO:0006412 (translation); GO:0032044 (DSIF complex); GO:0032784 (regulation of DNA-templated transcription elongation); GO:0140673 (transcription elongation-coupled chromatin remodeling)
KEGG	smil03250 (Viral life cycle - HIV-1 - Salvia miltiorrhiza (redroot sage))
Pfam	PF03439 (Spt5-NGN); PF11942 (Spt5_N); PF23037 (KOWx_SPT5); PF23038 (KOW6_SPT51-2); PF23042 (KOW1_SPT5); PF23284 (KOW2_Spt5); PF23287 (KOW7_SPT5); PF23290 (KOW5_SPT5); PF23291 (KOW4_SPT5)
InterPro	-
eggNOG	-
NR	GeneID:131011755

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057795574.1`
2	Nucleoplasm	核质	1.00000	`XP_057795574.1`
3	Nuclear speckle	核斑点	0.40000	`XP_057795574.1`
4	Chromosome	染色体	0.20000	`XP_057795574.1`
5	Chromatin	染色质	0.20000	`XP_057795574.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:47031913`	`G`	`A`	EMS_canonical_SNV	stop_gained	236	A1,A10,A11,A13,A14,A15,A16,A18,A19,A2,A20,A21,A22,A23,A24,A25,A3,A4,A5,A6,A7,A8,A9,B10,B100,B101,B102,B103,B104,B106,B107,B108,B109,B11,B110,B111,B112,B113,B114,B115,B117,B118,B119,B120,B121,B122,B124,B125,B126,B127,B128,B129,B13,B130,B131,B132,B133,B134,B136,B137,B14,B140,B16,B17,B18,B2,B20,B22,B23,B24,B25,B28,B29,B3,B30,B31,B32,B33,B34,B35,B36,B37,B38,B39,B4,B40,B41,B42,B43,B44,B46,B47,B48,B49,B50,B51,B52,B54,B55,B56,B57,B58,B59,B6,B60,B61,B62,B63,B64,B65,B66,B67,B68,B69,B7,B70,B71,B72,B73,B74,B75,B76,B77,B78,B79,B8,B80,B81,B82,B83,B84,B85,B86,B87,B88,B89,B9,B90,B91,B92,B93,B94,B95,B96,B97,B98,B99,C1,C10,C11,C13,C14,C15,C16,C17,C18,C19,C2,C20,C21,C22,C23,C24,C26,C27,C29,C3,C30,C31,C32,C33,C34,C35,C36,C37,C38,C39,C4,C40,C41,C42,C43,C44,C45,C46,C47,C48,C49,C5,C51,C52,C53,C54,C55,C56,C57,C58,C59,C6,C60,C61,C62,C63,C64,C65,C66,C67,C68,C7,C70,C71,C72,C73,C74,C75,C76,C78,C79,C8,C80,C81,C82,C83,C85,C86,C87,C9,D1,D10,D11,D2,D3,D4,D6,D8,D9
`Chr2:47031967`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A20,C83
`Chr2:47032085`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B1,C28
`Chr2:47032142`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A2,A7,B126
`Chr2:47032445`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B83
`Chr2:47032684`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B71
`Chr2:47033969`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B140
`Chr2:47035328`	`TGA`	`T`	2bp_deletion	frameshift_variant	1	B106
`Chr2:47035328`	`TGA`	`T`	2bp_deletion	CDS_variant	1	B106
`Chr2:47035427`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A2,A7,B126
`Chr2:47035448`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A16,B131,C30
`Chr2:47035664`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B83

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057795574.1

1040 aa

520

1040

Spt5_N

Spt5-NGN

KOW1_SPT5

KOW2_Spt5

KOWx_SPT5

KOW4_SPT5

KOW5_SPT5

KOW6_SPT51-2

KOW7_SPT5

PF11942 Spt5_N 89-174 aa PF03439 Spt5-NGN 180-261 aa PF23042 KOW1_SPT5 270-396 aa PF23284 KOW2_Spt5 424-473 aa PF23037 KOWx_SPT5 532-583 aa PF23291 KOW4_SPT5 590-644 aa PF23290 KOW5_SPT5 707-752 aa PF23038 KOW6_SPT51-2 934-984 aa PF23287 KOW7_SPT5 986-1037 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057795574.1`	Pfam	`PF11942`	Spt5_N	Disordered	89	174	5.4e-13	50.4	Spt5 transcription elongation factor, acidic N-terminal
`XP_057795574.1`	Pfam	`PF03439`	Spt5-NGN	Family	180	261	2.9e-26	91.9	Early transcription elongation factor of RNA pol II, NGN section
`XP_057795574.1`	Pfam	`PF23042`	KOW1_SPT5	Domain	270	396	8.4e-32	111.2	Transcription elongation factor SPT5, KOW1 domain
`XP_057795574.1`	Pfam	`PF23284`	KOW2_Spt5	Domain	424	473	3.8e-23	81.8	Transcription elongation factor SPT5, second KOW domain
`XP_057795574.1`	Pfam	`PF23037`	KOWx_SPT5	Domain	532	583	1.1e-17	64.1	Transcription elongation factor SPT5, KOWx domain
`XP_057795574.1`	Pfam	`PF23291`	KOW4_SPT5	Domain	590	644	2e-23	82.8	Transcription elongation factor SPT5, fourth KOW domain
`XP_057795574.1`	Pfam	`PF23290`	KOW5_SPT5	Domain	707	752	1e-17	64.1	Transcription elongation factor SPT5, fifth KOW domain
`XP_057795574.1`	Pfam	`PF23038`	KOW6_SPT51-2	Domain	934	984	3e-27	94.6	Transcription elongation factor SPT5 homolog 1/2, KOW6 domain
`XP_057795574.1`	Pfam	`PF23287`	KOW7_SPT5	Domain	986	1037	1.7e-22	79.7	Transcription elongation factor SPT5, seventh KOW domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057939591.1
ATGATGGAGTGGGATATCCAAATATGGAATCGCGGTCCATCCGGAATTAAAATGTTACTCCAGTATTCTGAAAAAATGAATATAGGCCTCGTCTGCGAAATTGTCATTTTTATCTCTCATCTACGCTGTGCCTGTTTCTAGGGCTTTTTTTCTCTCACACAGTTCATCAACCTCTCTCGAAAACTTATATATCTCACACCCCCACTCTCTCCAAATCAAATTCCATTCAATCACAAGCTTTCAATCCTCGCTCAATTGCC...

CDS

1 records

下载 CDS FASTA

LOC131011755
ATGCCGCGCCGGAGAGACGAATACGAGGACGACGGCGAAGACGAGGAGGAGTATGACGCCGTTGATGAAGAGGATGATGAGGCCGACGACTACAACGACGGGGGGAAGGTCAAACGGAAGCGGGGTAGATCAGATTTCATCGACGACGATGCGGATGAAGACCAGGAGGAAGACCAGGAGGAAGAGGACGACGACGATGAGGATTATGGCGGTGGCGGCAGCAGAGGAGGAGGAGGGAAGCGCCAAAGGAAGGCGGCCTC...

Protein

1 records

下载 Protein FASTA

XP_057795574.1
MPRRRDEYEDDGEDEEEYDAVDEEDDEADDYNDGGKVKRKRGRSDFIDDDADEDQEEDQEEEDDDDEDYGGGGSRGGGGKRQRKAASNFFDLEAQVDTDEEEEEEEGDDDFIDPGADIPDEDDRRIHRRPLLSREDEQEDVEEIERRIQERYARSLNVEYDEEATDVEQQALLPSVRDPKLWMVKCAIGREREVAVCLMQKCIDRGPELQIRSSVALDHLKNYIYIEADKEAHVKEAIKGMRNIFSGKIMLVPIKEMTDV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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