当前解析结果
SmilChr02G003328| 统一新 Gene ID | SmilChr02G003328 |
|---|---|
| 名称 | SmilChr02G003328 |
| 描述 | bifunctional aspartokinase/homoserine dehydrogenase, chloroplastic-like |
| 染色体 / SeqID | Chr02 / NC_080388.1 |
| 坐标与链方向 | 54528113 - 54534887 / - |
| NCBI Gene ID | LOC131010310 |
|---|---|
| GeneID | 131010310 |
| locus_tag | - |
| NCBI Name | LOC131010310 |
| 原始查询 | SmilChr02G003328 |
| 来源 | GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog |
|---|---|
| 描述 | bifunctional aspartokinase/homoserine dehydrogenase, chloroplastic-like |
| 产物 | bifunctional aspartokinase/homoserine dehydrogenase%2C chloroplastic-like |
| Arabidopsis | AT4G19710 (AK-HSDH II)aspartate kinase-homoserine dehydrogenase ii [Source:NCBI gene (formerly Entrezgene);Acc:827715] identity=75.5; qcov=1.01; evalue=0; confidence=high |
| Rice | Os08g0342400 (OJ1790_D02.29-2)- identity=77.3; qcov=0.93; evalue=0; confidence=high |
| GO | GO:0004072 (aspartate kinase activity); GO:0004412 (homoserine dehydrogenase activity); GO:0009067 (aspartate family amino acid biosynthetic process); GO:0009090 (L-homoserine biosynthetic process); GO:0050661 (NADP binding) |
| KEGG | smil00260 (Glycine, serine and threonine metabolism - Salvia miltiorrhiza (redroot sage)); smil00261 (Monobactam biosynthesis - Salvia miltiorrhiza (redroot sage)); smil00270 (Cysteine and methionine metabolism - Salvia miltiorrhiza (redroot sage)); smil00300 (Lysine biosynthesis - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage)) |
| Pfam | PF00696 (AA_kinase); PF00742 (Homoserine_dh); PF01842 (ACT); PF03447 (NAD_binding_3); PF13840 (ACT_7); PF22468 (ACT_9) |
| InterPro | - |
| eggNOG | - |
| NR | GeneID:131010310 |
| Rank | 定位位置 | 中文 | Score | Protein ID |
|---|---|---|---|---|
| 1 | Chloroplast | 叶绿体 | 1.00000 | XP_057793751.1 |
| 2 | Chloroplast stroma | 叶绿体基质 | 1.00000 | XP_057793751.1 |
| 3 | Nucleus | 细胞核 | 0.00000 | XP_057793751.1 |
| 4 | Chromosome | 染色体 | 0.00000 | XP_057793751.1 |
| 5 | Centromere | 着丝粒 | 0.00000 | XP_057793751.1 |
下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。
| 位置 | REF | ALT | 类型 | 影响 | 携带材料数 | 材料 |
|---|---|---|---|---|---|---|
Chr2:54528677 |
G |
A |
EMS_canonical_SNV | stop_gained | 1 | A9 |
Chr2:54528677 |
G |
A |
EMS_canonical_SNV | CDS_variant | 1 | A9 |
Chr2:54528979 |
C |
T |
EMS_canonical_SNV | CDS_variant | 1 | C48 |
Chr2:54529463 |
C |
T |
EMS_canonical_SNV | CDS_variant | 1 | C49 |
Chr2:54529480 |
C |
CAT |
2bp_insertion | frameshift_variant | 1 | B26 |
Chr2:54529480 |
C |
CAT |
2bp_insertion | CDS_variant | 1 | B26 |
Chr2:54529481 |
G |
A |
EMS_canonical_SNV | CDS_variant | 5 | A11,B31,B45,C64,C66 |
Chr2:54529728 |
G |
A |
EMS_canonical_SNV | CDS_variant | 1 | B2 |
Chr2:54530225 |
CT |
C |
1bp_deletion | frameshift_variant | 216 | A1,A10,A13,A14,A15,A16,A18,A2,A21,A22,A23,A24,A4,A5,A6,A7,A8,A9,B1,B100,B101,B103,B104,B105,B106,B107,B108,B11,B110,B111,B112,B113,B115,B117,B118,B12,B120,B121,B122,B123,B124,B126,B127,B128,B130,B133,B135,B136,B137,B138,B139,B14,B140,B15,B16,B17,B18,B19,B2,B20,B21,B22,B23,B24,B25,B26,B27,B28,B29,B30,B31,B32,B33,B34,B35,B37,B38,B39,B4,B40,B41,B42,B44,B45,B46,B47,B48,B49,B5,B50,B52,B54,B55,B56,B57,B58,B6,B60,B61,B63,B64,B66,B67,B69,B7,B70,B72,B73,B74,B75,B77,B78,B79,B8,B80,B82,B83,B85,B86,B88,B89,B9,B90,B91,B95,B97,B98,B99,C1,C10,C11,C13,C15,C16,C17,C19,C2,C21,C22,C23,C24,C25,C26,C27,C28,C29,C3,C30,C31,C32,C33,C34,C35,C36,C37,C38,C39,C4,C40,C41,C42,C43,C44,C45,C46,C47,C48,C49,C5,C50,C51,C52,C53,C54,C55,C56,C58,C59,C6,C60,C61,C63,C64,C65,C66,C67,C69,C7,C70,C71,C72,C73,C74,C75,C76,C77,C78,C79,C8,C80,C81,C83,C84,C85,C86,C87,C9,D1,D10,D2,D3,D5,D6,D7,D8,D9 |
Chr2:54530418 |
C |
T |
EMS_canonical_SNV | CDS_variant | 1 | B107 |
Chr2:54530589 |
G |
A |
EMS_canonical_SNV | CDS_variant | 1 | C48 |
Chr2:54530600 |
C |
T |
EMS_canonical_SNV | CDS_variant | 1 | C86 |
结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。
XP_057793751.1PF00696
AA_kinase 88-368 aa
PF22468
ACT_9 407-467 aa
PF13840
ACT_7 483-546 aa
PF22468
ACT_9 489-548 aa
PF01842
ACT 495-544 aa
PF03447
NAD_binding_3 561-697 aa
PF00742
Homoserine_dh 705-903 aa
| Protein ID | 来源 | 结构域编号 | 结构域名称 | 类型 | 起始 aa | 终止 aa | E-value | Score | 说明 |
|---|---|---|---|---|---|---|---|---|---|
XP_057793751.1 |
Pfam | PF00696 |
AA_kinase | Family | 88 | 368 | 5.2e-43 | 148.2 | Amino acid kinase family |
XP_057793751.1 |
Pfam | PF22468 |
ACT_9 | Domain | 407 | 467 | 1.1e-41 | 141.0 | ACT domain |
XP_057793751.1 |
Pfam | PF13840 |
ACT_7 | Domain | 483 | 546 | 1.4e-17 | 64.0 | ACT domain |
XP_057793751.1 |
Pfam | PF22468 |
ACT_9 | Domain | 489 | 548 | 1.1e-41 | 141.0 | ACT domain |
XP_057793751.1 |
Pfam | PF01842 |
ACT | Domain | 495 | 544 | 2.2e-14 | 53.6 | ACT domain |
XP_057793751.1 |
Pfam | PF03447 |
NAD_binding_3 | Domain | 561 | 697 | 1.3e-21 | 78.2 | Homoserine dehydrogenase, NAD binding domain |
XP_057793751.1 |
Pfam | PF00742 |
Homoserine_dh | Domain | 705 | 903 | 1e-54 | 185.8 | Homoserine dehydrogenase |
每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。
1 records
下载 cDNA FASTA1 records
下载 CDS FASTA1 records
下载 Protein FASTAupstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。