Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G003528`

染色体: Chr02 坐标: 56428308-56429727 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G003528`
名称	SmilChr02G003528
描述	isoflavone reductase-like protein
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	56428308 - 56429727 / `+`

ID 对照

NCBI Gene ID	`LOC131010492`
GeneID	`131010492`
locus_tag	`-`
NCBI Name	`LOC131010492`
原始查询	`SmilChr02G003528`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	isoflavone reductase-like protein
产物	isoflavone reductase-like protein
Arabidopsis	`AT1G75290` (AT1G75290) NAD(P)-binding Rossmann-fold superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:843866] identity=67.1; qcov=0.993; evalue=3.86e-151; confidence=high
Rice	`Os06g0472200` - identity=58.1; qcov=0.99; evalue=6.52e-131; confidence=high
GO	GO:0016491 (oxidoreductase activity)
KEGG	-
Pfam	PF01073 (3Beta_HSD); PF01370 (Epimerase); PF03435 (Sacchrp_dh_NADP); PF05368 (NmrA); PF13460 (NAD_binding_10); PF16363 (GDP_Man_Dehyd)
InterPro	-
eggNOG	-
NR	GeneID:131010492

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057794009.1`
2	Cytoplasm	细胞质	0.60000	`XP_057794009.1`
3	Nucleus	细胞核	0.00000	`XP_057794009.1`
4	Chromosome	染色体	0.00000	`XP_057794009.1`
5	Centromere	着丝粒	0.00000	`XP_057794009.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:56428447`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B57,C65
`Chr2:56428513`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C43
`Chr2:56428570`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C27,C3
`Chr2:56428599`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C52
`Chr2:56428700`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B120,B85,B9,C43,C56
`Chr2:56429017`	`CAG`	`C`	2bp_deletion	frameshift_variant	1	B57
`Chr2:56429017`	`CAG`	`C`	2bp_deletion	CDS_variant	1	B57
`Chr2:56429399`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A7,B11,C42,C56
`Chr2:56429405`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B112,B14,B41,D8
`Chr2:56429415`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B3
`Chr2:56429418`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A22,B138,B23,C1,C41

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057794009.1

306 aa

153

306

NmrA

Epimerase

Sacchrp_dh_NADP

GDP_Man_Dehyd

3Beta_HSD

NAD_binding_10

PF05368 NmrA 3-302 aa PF01370 Epimerase 5-83 aa PF03435 Sacchrp_dh_NADP 5-89 aa PF16363 GDP_Man_Dehyd 6-76 aa PF01073 3Beta_HSD 6-91 aa PF13460 NAD_binding_10 9-148 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057794009.1`	Pfam	`PF05368`	NmrA	Family	3	302	6.8e-94	315.5	NmrA-like family
`XP_057794009.1`	Pfam	`PF01370`	Epimerase	Family	5	83	9.5e-09	35.7	NAD dependent epimerase/dehydratase family
`XP_057794009.1`	Pfam	`PF03435`	Sacchrp_dh_NADP	Family	5	89	2.1e-06	28.8	Saccharopine dehydrogenase NADP binding domain
`XP_057794009.1`	Pfam	`PF16363`	GDP_Man_Dehyd	Domain	6	76	2e-07	31.5	GDP-mannose 4,6 dehydratase
`XP_057794009.1`	Pfam	`PF01073`	3Beta_HSD	Family	6	91	8.6e-07	29.0	3-beta hydroxysteroid dehydrogenase/isomerase family
`XP_057794009.1`	Pfam	`PF13460`	NAD_binding_10	Domain	9	148	4.2e-13	50.3	NAD(P)H-binding

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057938026.1
TTAGTTATTTATATGTGAACCCATCTCACACTAATTCATCATCAAACTCAGCAATTGTAAGTCATAGCAGAGTTTTCAAGAAGAAGAAAAAAAAAGTTTCACATAAAGATAGAAAAATGGGAGAGAAGATCTTGATCATCGGTGGAACAGGATACATCGGCAAATTCGTAGTTGAGGCCAGCGCTAAATCTGGGCATCCCACTTTCGCTTTGATGAGAGAGGCATCCCTCTCTGATCCAGCCAAATCTGAGCTCGTCGAA...

CDS

1 records

下载 CDS FASTA

LOC131010492
ATGGGAGAGAAGATCTTGATCATCGGTGGAACAGGATACATCGGCAAATTCGTAGTTGAGGCCAGCGCTAAATCTGGGCATCCCACTTTCGCTTTGATGAGAGAGGCATCCCTCTCTGATCCAGCCAAATCTGAGCTCGTCGAAACCTTCAAGAAATCTGGTGTCACCTTCCTAACTGGAGATCTGAATGATCACGAGAGCTTGGTGAAGGCTATAAAGCAAGTGGATGTGGTTATATCAACCGTGGGCTTCATGCAGAT...

Protein

1 records

下载 Protein FASTA

XP_057794009.1
MGEKILIIGGTGYIGKFVVEASAKSGHPTFALMREASLSDPAKSELVETFKKSGVTFLTGDLNDHESLVKAIKQVDVVISTVGFMQIADQYKIIAAIKEAGNVKRFLPSEFGNDLDRCRAVDPINQNFQLKVQLRRAIEAEGIPYTYIVCNLFAGYALSNFLQLGATAPPRDKIVIPGDGNVKAVFNEEHDIGAYTVKASVDPRTLNKILYIKPPHNIYSFNELVACWEKKIGNTLEKIYVAEDELLKQIEESPMPVNVI...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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