Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G003648`

染色体: Chr02 坐标: 57854246-57870384 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G003648`
名称	SmilChr02G003648
描述	E3 ubiquitin-protein ligase UPL2-like
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	57854246 - 57870384 / `-`

ID 对照

NCBI Gene ID	`LOC131010605`
GeneID	`131010605`
locus_tag	`-`
NCBI Name	`LOC131010605`
原始查询	`SmilChr02G003648`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	E3 ubiquitin-protein ligase UPL2-like
产物	E3 ubiquitin-protein ligase UPL2-like
Arabidopsis	`AT1G70320` (UPL2) ubiquitin-protein ligase 2 [Source:NCBI gene (formerly Entrezgene);Acc:843368] identity=35.9; qcov=0.59; evalue=0; confidence=medium
Rice	`Os12g0428600` - identity=60.2; qcov=1.01; evalue=0; confidence=high
GO	GO:0000209 (protein polyubiquitination); GO:0004842 (ubiquitin-protein transferase activity); GO:0005515 (protein binding); GO:0043161 (proteasome-mediated ubiquitin-dependent protein catabolic process); GO:0045732 (positive regulation of protein catabolic process)
KEGG	smil04120 (Ubiquitin mediated proteolysis - Salvia miltiorrhiza (redroot sage))
Pfam	PF00627 (UBA); PF00632 (HECT); PF06012 (DUF908); PF06025 (DUF913); PF14377 (UBM); PF22562 (UBA_7)
InterPro	-
eggNOG	-
NR	GeneID:131010605

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057794190.1`
2	Cytoplasm	细胞质	0.60000	`XP_057794190.1`
3	Cytosol	细胞质基质	0.20000	`XP_057794190.1`
4	Chromosome	染色体	0.00000	`XP_057794190.1`
5	Centromere	着丝粒	0.00000	`XP_057794190.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:57854517`	`TG`	`T`	1bp_deletion	frameshift_variant	1	B61
`Chr2:57854517`	`TG`	`T`	1bp_deletion	CDS_variant	1	B61
`Chr2:57854709`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B36,C71
`Chr2:57855550`	`CT`	`C`	1bp_deletion	frameshift_variant	1	B51
`Chr2:57855550`	`CT`	`C`	1bp_deletion	CDS_variant	1	B51
`Chr2:57855907`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	A7,C83
`Chr2:57856351`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C48
`Chr2:57856996`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B107,B140
`Chr2:57857134`	`AC`	`A`	1bp_deletion	frameshift_variant	1	B43
`Chr2:57857134`	`AC`	`A`	1bp_deletion	CDS_variant	1	B43
`Chr2:57857815`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B55
`Chr2:57858214`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C71

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057794190.1

3636 aa

1818

3636

DUF908

DUF913

UBA

UBA_7

UBM

HECT

PF06012 DUF908 106-159 aa PF06012 DUF908 233-409 aa PF06025 DUF913 476-805 aa PF00627 UBA 1302-1339 aa PF22562 UBA_7 1303-1350 aa PF14377 UBM 2563-2588 aa PF14377 UBM 2599-2629 aa PF14377 UBM 2637-2668 aa PF00632 HECT 3325-3635 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057794190.1`	Pfam	`PF06012`	DUF908	Family	106	159	2.1e-28	100.5	Domain of Unknown Function (DUF908)
`XP_057794190.1`	Pfam	`PF06012`	DUF908	Family	233	409	2.1e-28	100.5	Domain of Unknown Function (DUF908)
`XP_057794190.1`	Pfam	`PF06025`	DUF913	Family	476	805	5.3e-62	210.7	Domain of Unknown Function (DUF913)
`XP_057794190.1`	Pfam	`PF00627`	UBA	Domain	1302	1339	1.6e-09	38.1	UBA/TS-N domain
`XP_057794190.1`	Pfam	`PF22562`	UBA_7	Domain	1303	1350	3e-15	56.5	UBA-like domain
`XP_057794190.1`	Pfam	`PF14377`	UBM	Motif	2563	2588	4e-28	96.6	Ubiquitin binding region
`XP_057794190.1`	Pfam	`PF14377`	UBM	Motif	2599	2629	4e-28	96.6	Ubiquitin binding region
`XP_057794190.1`	Pfam	`PF14377`	UBM	Motif	2637	2668	4e-28	96.6	Ubiquitin binding region
`XP_057794190.1`	Pfam	`PF00632`	HECT	Domain	3325	3635	3.7e-98	329.7	HECT-domain (ubiquitin-transferase)

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057938207.1
TGTGTATATACTCTCGAGTGTTTGTGTGTGAAAGGTTAGAACCCTTTGGCTTTTCCAGGGTTACACCTCCACTTCCGCAAGAACAACTTCGCACACAAGAGATAAAATTAAACCCACTATTTATTGGGGTTTCCCTCAGACGCCTCTTTCTCTCTCTACCTATACATACAACACACCACTGTCCATATATATATAGATTACATATATCTATTGTTTTGTACAGTGCAAGACCCGCTAGATGTGCAAGCGTGCGCTGTGTT...

CDS

1 records

下载 CDS FASTA

LOC131010605
ATGGCGAGTATAAGATCGAGCTTGCCGTCAAGGCTTCGGCAACTCCTCTCTAGTGAAGGGGCAATCGGCCCCTCTGTTAAACTTGACACAGAGCCTCCTCCAAGAATAAAGGTTTTTATCGACAAGGTGATTCAGTGCCCATTACAGGATATAGCGATACCTCTCTCTGGTTTTCGCTGGGAGTATGGCAAGGGAAATTTCCACCATTGGAGACCTCTATTTCTGCACTTTGATACATATTTCAAGACACATTTATCTTG...

Protein

1 records

下载 Protein FASTA

XP_057794190.1
MASIRSSLPSRLRQLLSSEGAIGPSVKLDTEPPPRIKVFIDKVIQCPLQDIAIPLSGFRWEYGKGNFHHWRPLFLHFDTYFKTHLSCRNDLLLSDDILGDVSPFPKQAVLQILRVMQIILENCHNKSSFSVIEHFKLLLASTDPEIITAALETLSALVKISPSKLHVSGKLVGCGSVNTCLLSLAQGWGSKEEGLGLYSCVTLHERTQEDGLCLFPSEAQNDSDKLQNRVGSTLYFELRSSSPSDVEASDSTNSSGVRVI...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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