Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G004305`

染色体: Chr02 坐标: 65431365-65443597 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G004305`
名称	SmilChr02G004305
描述	protein CHROMATIN REMODELING 4-like
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	65431365 - 65443597 / `+`

ID 对照

NCBI Gene ID	`LOC131013046`
GeneID	`131013046`
locus_tag	`-`
NCBI Name	`LOC131013046`
原始查询	`SmilChr02G004305`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	protein CHROMATIN REMODELING 4-like
产物	protein CHROMATIN REMODELING 4-like
Arabidopsis	`AT5G44800` (CHR4) chromatin remodeling 4 [Source:NCBI gene (formerly Entrezgene);Acc:834510] identity=49.4; qcov=1; evalue=0; confidence=high
Rice	`Os01g0367900` - identity=41.2; qcov=0.241; evalue=1.89e-109; confidence=weak
GO	GO:0000122 (negative regulation of transcription by RNA polymerase II); GO:0000785 (chromatin); GO:0003677 (DNA binding); GO:0003682 (chromatin binding); GO:0005524 (ATP binding); GO:0005634 (nucleus); GO:0006338 (chromatin remodeling); GO:0016887 (ATP hydrolysis activity); GO:0042393 (histone binding); GO:0140658 (ATP-dependent chromatin remodeler activity)
KEGG	-
Pfam	PF00176 (SNF2-rel_dom); PF00271 (Helicase_C); PF00385 (Chromo); PF00628 (PHD); PF04851 (ResIII); PF06465 (DUF1087); PF11496 (HDA2-3)
InterPro	-
eggNOG	-
NR	GeneID:131013046

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057797026.1`
2	Nucleoplasm	核质	0.20000	`XP_057797026.1`
3	Chromosome	染色体	0.00000	`XP_057797026.1`
4	Centromere	着丝粒	0.00000	`XP_057797026.1`
5	Chromatin	染色质	0.00000	`XP_057797026.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:65432887`	`GA`	`G`	1bp_deletion	frameshift_variant	1	B93
`Chr2:65432887`	`GA`	`G`	1bp_deletion	CDS_variant	1	B93
`Chr2:65433015`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B40,B60,B79,C71,C76
`Chr2:65433043`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr2:65433662`	`G`	`A`	EMS_canonical_SNV	stop_gained	1	C4
`Chr2:65433662`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C4
`Chr2:65433774`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B109
`Chr2:65433881`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B7
`Chr2:65434139`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C47
`Chr2:65434393`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C87
`Chr2:65435429`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A7,B73,C60,D3
`Chr2:65435666`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A10,B120,B77

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057797026.1

2274 aa

1137

2274

PHD

Chromo

ResIII

SNF2-rel_dom

HDA2-3

Helicase_C

DUF1087

PF00628 PHD 77-118 aa PF00385 Chromo 593-628 aa PF00385 Chromo 645-694 aa PF04851 ResIII 737-908 aa PF00176 SNF2-rel_dom 740-1029 aa PF11496 HDA2-3 977-1194 aa PF00271 Helicase_C 1054-1167 aa PF06465 DUF1087 1354-1389 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057797026.1`	Pfam	`PF00628`	PHD	Domain	77	118	1.3e-08	35.4	PHD-finger
`XP_057797026.1`	Pfam	`PF00385`	Chromo	Domain	593	628	2.8e-15	56.7	Chromo (CHRromatin Organisation MOdifier) domain
`XP_057797026.1`	Pfam	`PF00385`	Chromo	Domain	645	694	2.8e-15	56.7	Chromo (CHRromatin Organisation MOdifier) domain
`XP_057797026.1`	Pfam	`PF04851`	ResIII	Family	737	908	7.5e-09	36.4	Type III restriction enzyme, res subunit
`XP_057797026.1`	Pfam	`PF00176`	SNF2-rel_dom	Domain	740	1029	2.1e-77	260.8	SNF2-related domain
`XP_057797026.1`	Pfam	`PF11496`	HDA2-3	Domain	977	1194	9.7e-12	45.4	Class II histone deacetylase complex subunits 2 and 3
`XP_057797026.1`	Pfam	`PF00271`	Helicase_C	Domain	1054	1167	9.9e-24	84.4	Helicase conserved C-terminal domain
`XP_057797026.1`	Pfam	`PF06465`	DUF1087	Domain	1354	1389	6.5e-07	30.1	CHD subfamily II, DUF1087

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057941043.1
TGAATTTCAATCTCAGACTTTATTAATAGCAATATTCCTTATACTCCCACGCAATCTAATCTGACTTTCTCTATTAATACGAACTGGCAAGTAGCAAGTGGTGATTATTCCACAAAATCGAAGCAAGATTCCTTTTTTTCGGGCAATTAAATCTAAGCAAAGATCAAACAATAATTGCAGAGTTGGGCGCTAAATCCAGAAGCGAAAAAAGGAAAAGAAAGGGATTTTGAGGTGGAGCGAATAAGGACGATGAGGATTAG...

CDS

1 records

下载 CDS FASTA

LOC131013046
ATGAAGGAAAATGGTTCAGAGAATAGTACCATGCTTAATAGAAACTGGGTGTTGAAACGGAAGCGTAGGAAGCTTCCATCCGGCACAGATAAGTCTCGTGACAGAGGGAAAATATTCAGACCTGTAAAATTTTCATCCACTACTAGATTAAAGAATGACAAGGAAGAGGATGATAATCTAGAGCAAACTTCTGGGAAGAAAAAAGGCAACGATGGGTATTATTACGAGTGTGTGGTCTGCGAACTTGGTGGAAAGTTGCT...

Protein

1 records

下载 Protein FASTA

XP_057797026.1
MKENGSENSTMLNRNWVLKRKRRKLPSGTDKSRDRGKIFRPVKFSSTTRLKNDKEEDDNLEQTSGKKKGNDGYYYECVVCELGGKLLCCDSCPRTYHLECLDPALKRIPTGKWECPTCIQQHSCVESVNHLDPVSKRARTKIIIRRSKTEAESSATDKVTETFDAPILRKKRNSDKGKSPASRRSRTIEKLDSSSNDFCHNDQLNPVQDGSVDASSSHDVNEKEQVSHALVQAQNMKAPVKGSLSKKKKSKMNVGSTDLN...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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