Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G004425`

染色体: Chr02 坐标: 66586220-66589870 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G004425`
名称	SmilChr02G004425
描述	hexokinase-2
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	66586220 - 66589870 / `+`

ID 对照

NCBI Gene ID	`LOC131013177`
GeneID	`131013177`
locus_tag	`-`
NCBI Name	`LOC131013177`
原始查询	`SmilChr02G004425`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	hexokinase-2
产物	hexokinase-2
Arabidopsis	`AT4G29130` (HXK1) hexokinase 1 [Source:NCBI gene (formerly Entrezgene);Acc:829034] identity=72; qcov=1; evalue=0; confidence=high
Rice	`Os05g0532600` (OsHXK2) - identity=67.6; qcov=0.952; evalue=0; confidence=high
GO	GO:0001678 (intracellular glucose homeostasis); GO:0004340 (glucokinase activity); GO:0005524 (ATP binding); GO:0005536 (D-glucose binding); GO:0005739 (mitochondrion); GO:0005829 (cytosol); GO:0006096 (glycolytic process); GO:0008865 (fructokinase activity); GO:0019158 (mannokinase activity); GO:0051156 (glucose 6-phosphate metabolic process)
KEGG	smil00010 (Glycolysis / Gluconeogenesis - Salvia miltiorrhiza (redroot sage)); smil00051 (Fructose and mannose metabolism - Salvia miltiorrhiza (redroot sage)); smil00052 (Galactose metabolism - Salvia miltiorrhiza (redroot sage)); smil00500 (Starch and sucrose metabolism - Salvia miltiorrhiza (redroot sage)); smil00520 (Amino sugar and nucleotide sugar metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01250 (Biosynthesis of nucleotide sugars - Salvia miltiorrhiza (redroot sage))
Pfam	PF00349 (Hexokinase_1); PF03727 (Hexokinase_2)
InterPro	-
eggNOG	-
NR	GeneID:131013177

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	0.60000	`XP_057797211.1`
2	Cytoplasm	细胞质	0.20000	`XP_057797211.1`
3	Cytosol	细胞质基质	0.20000	`XP_057797211.1`
4	Mitochondrion membrane	线粒体膜	0.20000	`XP_057797211.1`
5	Mitochondrion outer membrane	线粒体外膜	0.20000	`XP_057797211.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:66586625`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B122,C30
`Chr2:66586626`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B85
`Chr2:66586706`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A21,B53,B71,C45
`Chr2:66586727`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B121,C80
`Chr2:66586872`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C79
`Chr2:66588535`	`GAC`	`G`	2bp_deletion	frameshift_variant	27	A10,A2,B1,B10,B119,B131,B26,B32,B33,B35,B39,B49,B52,B6,B79,B85,B96,B97,C1,C29,C32,C33,C40,C49,C66,C84,D10
`Chr2:66588539`	`TTG`	`T`	2bp_deletion	frameshift_variant	28	A10,A2,B1,B10,B119,B131,B26,B32,B33,B35,B39,B49,B52,B6,B79,B85,B96,B97,C1,C29,C32,C33,C40,C46,C49,C66,C84,D10
`Chr2:66589221`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B65,C37
`Chr2:66589258`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B2,B41,C16,C49,D5
`Chr2:66589513`	`AT`	`A`	1bp_deletion	frameshift_variant	1	C65
`Chr2:66589513`	`AT`	`A`	1bp_deletion	CDS_variant	1	C65
`Chr2:66589515`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C65

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057797211.1

496 aa

248

496

Hexokinase_1

Hexokinase_2

PF00349 Hexokinase_1 41-238 aa PF03727 Hexokinase_2 247-486 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057797211.1`	Pfam	`PF00349`	Hexokinase_1	Domain	41	238	3.4e-73	246.4	Hexokinase
`XP_057797211.1`	Pfam	`PF03727`	Hexokinase_2	Domain	247	486	3e-83	279.6	Hexokinase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057941228.1
CAAAATTTCCAAATCCTTTTACAATAAGGAATCAAATTTGATAAATGCAAGAAAATCAGCAAAAATAAGGAAAAAAATAAAAAACGTGAAGATCTCCAAAAATAGGGAGCAAAGCTTCAATGGCGGAGTTTCCACCTCGACACTTGAAAGTAAAGAAAACCCAACCCACTCAACTCAACAAACCATCCACAATAAACACTTTCTTTCCATTCTTTCTCGTTCCAGAATAAAACCCAATTACTCTATTTTCCCGTGATTTG...

CDS

1 records

下载 CDS FASTA

LOC131013177
ATGGGGAAGGTGGCGGTCGGGGTGGCAGTGATCGGGACCGCTGCGGTGGTGGCCGCGGCGGCACTGGTGGTGCGGCAGCGGATGAGGAGTTCTGGGAGGTGGGCCCGGACGAGGGCGTTGGTGAAGGAGTTTGAGGAGAAATGTGGGACCCCCGAGGCCAAATTGAAGCAGGTTGCAGATGCGATGACTGTGGAAATGCATGCGGGTTTGGCATCTGAGGGTGGCAGCAAGCTCAAGATGCTCATCAGTTTTGTTGATAA...

Protein

1 records

下载 Protein FASTA

XP_057797211.1
MGKVAVGVAVIGTAAVVAAAALVVRQRMRSSGRWARTRALVKEFEEKCGTPEAKLKQVADAMTVEMHAGLASEGGSKLKMLISFVDNLPTGDEEGVFYALDLGGTNFRVLRVELGGRERGVVHQEFAEASIPPALMSGSSDALFDYIADKLAEFVADEERIYEQPAGKERELGFTFSFPVMQTSINSGTLIRWTKGFSIDDTVGQDVVAEVTKALKRKGVDMRVAALVNDTIGTLAGGRHADPDVSIAVILGTGTNAAYV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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