Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G004451`

染色体: Chr02 坐标: 66864139-66867128 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G004451`
名称	SmilChr02G004451
描述	wall-associated receptor kinase-like 1
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	66864139 - 66867128 / `-`

ID 对照

NCBI Gene ID	`LOC131013198`
GeneID	`131013198`
locus_tag	`-`
NCBI Name	`LOC131013198`
原始查询	`SmilChr02G004451`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	wall-associated receptor kinase-like 1
产物	wall-associated receptor kinase-like 1
Arabidopsis	`AT1G16130` (WAKL2) wall associated kinase-like 2 [Source:NCBI gene (formerly Entrezgene);Acc:838182] identity=39.7; qcov=1.02; evalue=4.84e-167; confidence=medium
Rice	`Os02g0111600` (OsWAK11) - identity=38.5; qcov=0.968; evalue=2.94e-156; confidence=medium
GO	GO:0004674 (protein serine/threonine kinase activity); GO:0005509 (calcium ion binding); GO:0005524 (ATP binding); GO:0005886 (plasma membrane); GO:0006468 (protein phosphorylation); GO:0007166 (cell surface receptor signaling pathway); GO:0030247 (polysaccharide binding)
KEGG	-
Pfam	PF00008 (EGF); PF00069 (Pkinase); PF07645 (EGF_CA); PF07714 (PK_Tyr_Ser-Thr); PF12947 (EGF_3); PF13947 (GUB_WAK_bind)
InterPro	-
eggNOG	-
NR	GeneID:131013198

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057797246.1`
2	Nucleus	细胞核	0.00000	`XP_057797246.1`
3	Chromosome	染色体	0.00000	`XP_057797246.1`
4	Centromere	着丝粒	0.00000	`XP_057797246.1`
5	Chromatin	染色质	0.00000	`XP_057797246.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:66864196`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A18,B136,B56,B96,C20
`Chr2:66864241`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B104,B109,B46,B69,B84
`Chr2:66864303`	`AC`	`A`	1bp_deletion	frameshift_variant	7	B104,B109,B46,B69,B84,C79,D11
`Chr2:66864538`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B84,D3
`Chr2:66864643`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B35
`Chr2:66864776`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr2:66864792`	`TG`	`T`	1bp_deletion	frameshift_variant	2	B46,B69
`Chr2:66864792`	`TG`	`T`	1bp_deletion	CDS_variant	2	B46,B69
`Chr2:66864795`	`AG`	`A`	1bp_deletion	frameshift_variant	2	B46,B69
`Chr2:66864795`	`AG`	`A`	1bp_deletion	CDS_variant	2	B46,B69
`Chr2:66864810`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B84,D3
`Chr2:66864866`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B84,D3

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057797246.1

773 aa

386

773

GUB_WAK_bind

EGF_CA

EGF

EGF_3

Pkinase

PK_Tyr_Ser-Thr

PF13947 GUB_WAK_bind 26-80 aa PF07645 EGF_CA 323-357 aa PF00008 EGF 327-356 aa PF12947 EGF_3 327-358 aa PF00069 Pkinase 444-711 aa PF07714 PK_Tyr_Ser-Thr 447-714 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057797246.1`	Pfam	`PF13947`	GUB_WAK_bind	Domain	26	80	1.1e-09	39.3	Wall-associated receptor kinase galacturonan-binding
`XP_057797246.1`	Pfam	`PF07645`	EGF_CA	Domain	323	357	6.2e-09	36.7	Calcium-binding EGF domain
`XP_057797246.1`	Pfam	`PF00008`	EGF	Domain	327	356	2.9e-07	31.3	EGF-like domain
`XP_057797246.1`	Pfam	`PF12947`	EGF_3	Domain	327	358	1.9e-08	35.1	EGF domain
`XP_057797246.1`	Pfam	`PF00069`	Pkinase	Domain	444	711	3.1e-49	168.4	Protein kinase domain
`XP_057797246.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	447	714	6e-47	160.8	Protein tyrosine and serine/threonine kinase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057941263.1
ATCGTGGCTGTCTCGAAAAGAGGACAAAAATAAAATAATGGGATGCACAGTCAGATCCGTCATCTGTGTGTACGGTGGCTGTCTCTGAAATTATTGGTCTAACAATTGAAACTTTAAATATGTGATGATTCACTATTGCGAAAATTATCCAATAGGATGATTCTACAACTTTGTTTCCTCCAATATTTGATTTCATCATTTTCGTGGGGCGCTGTAATTCCTAAAGAGGGATGCCCGGAGCGATGCGGGGATGTGGCAAT...

CDS

1 records

下载 CDS FASTA

LOC131013198
ATGATTCTACAACTTTGTTTCCTCCAATATTTGATTTCATCATTTTCGTGGGGCGCTGTAATTCCTAAAGAGGGATGCCCGGAGCGATGCGGGGATGTGGCAATTCCATTTCCATTCGGAGTGGGGTCGGAGTGCTCGCTGGGAGAGTATTTCAACATCACCTGCAATATGTCGAAACCCTACCTCTTCTCTTTTGATGGTTTAGAAGTGGTGGAGATAAATCCATCACAAGTCCGAGTTCGTTTTAAGCAGGTGCTGAA...

Protein

1 records

下载 Protein FASTA

XP_057797246.1
MILQLCFLQYLISSFSWGAVIPKEGCPERCGDVAIPFPFGVGSECSLGEYFNITCNMSKPYLFSFDGLEVVEINPSQVRVRFKQVLNSACYNGSVAGNPTREGGSRTSYGYSFYNSPYVFSDDNWLTAIGCNHMLTTFTMDDAAFDHYQQTYGGSCASFCMNPNDSTTVCPPTDAPYPPGNACCFISIPKGMTQVSSELANLDRGVGPFGDGKVSSCSYAFLQEKVRPNESTVSYPLSFLNNSNEFLQDGWTWKNRVAPP...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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