Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G004452`

染色体: Chr02 坐标: 66877644-66882127 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G004452`
名称	SmilChr02G004452
描述	wall-associated receptor kinase-like 8
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	66877644 - 66882127 / `-`

ID 对照

NCBI Gene ID	`LOC131013199`
GeneID	`131013199`
locus_tag	`-`
NCBI Name	`LOC131013199`
原始查询	`SmilChr02G004452`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	wall-associated receptor kinase-like 8
产物	wall-associated receptor kinase-like 8
Arabidopsis	`AT1G16130` (WAKL2) wall associated kinase-like 2 [Source:NCBI gene (formerly Entrezgene);Acc:838182] identity=40.7; qcov=0.971; evalue=4.41e-158; confidence=medium
Rice	`Os04g0598900` (OsWAK50) - identity=41.1; qcov=0.947; evalue=8.16e-166; confidence=medium
GO	GO:0004674 (protein serine/threonine kinase activity); GO:0005509 (calcium ion binding); GO:0005524 (ATP binding); GO:0005886 (plasma membrane); GO:0006468 (protein phosphorylation); GO:0007166 (cell surface receptor signaling pathway); GO:0030247 (polysaccharide binding)
KEGG	-
Pfam	PF00069 (Pkinase); PF07645 (EGF_CA); PF07714 (PK_Tyr_Ser-Thr); PF12947 (EGF_3); PF13947 (GUB_WAK_bind)
InterPro	-
eggNOG	-
NR	GeneID:131013199

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057797247.1`
2	Nucleus	细胞核	0.00000	`XP_057797247.1`
3	Chromosome	染色体	0.00000	`XP_057797247.1`
4	Centromere	着丝粒	0.00000	`XP_057797247.1`
5	Chromatin	染色质	0.00000	`XP_057797247.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:66877882`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B29
`Chr2:66877928`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B14,B46,B69
`Chr2:66878074`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A21,B53,B71,C45
`Chr2:66878140`	`G`	`A`	EMS_canonical_SNV	stop_gained	4	A21,B53,B71,C45
`Chr2:66878140`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A21,B53,B71,C45
`Chr2:66878145`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A21
`Chr2:66878225`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B46,B69,B84,C79,D11
`Chr2:66878254`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B1,B20,C37,C44,C8
`Chr2:66878359`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A10,B35,C2,C32,C68
`Chr2:66878369`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B4
`Chr2:66878496`	`T`	`TTA`	2bp_insertion	frameshift_variant	7	A18,B45,B47,C35,C4,C85,D6
`Chr2:66878597`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B94,B98,D4

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057797247.1

755 aa

378

755

GUB_WAK_bind

EGF_CA

EGF_3

Pkinase

PK_Tyr_Ser-Thr

PF13947 GUB_WAK_bind 28-88 aa PF07645 EGF_CA 316-358 aa PF12947 EGF_3 324-354 aa PF00069 Pkinase 440-705 aa PF07714 PK_Tyr_Ser-Thr 443-708 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057797247.1`	Pfam	`PF13947`	GUB_WAK_bind	Domain	28	88	2.5e-09	38.1	Wall-associated receptor kinase galacturonan-binding
`XP_057797247.1`	Pfam	`PF07645`	EGF_CA	Domain	316	358	7.8e-08	33.2	Calcium-binding EGF domain
`XP_057797247.1`	Pfam	`PF12947`	EGF_3	Domain	324	354	8.1e-11	42.7	EGF domain
`XP_057797247.1`	Pfam	`PF00069`	Pkinase	Domain	440	705	1.6e-51	176.0	Protein kinase domain
`XP_057797247.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	443	708	2.3e-49	168.7	Protein tyrosine and serine/threonine kinase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057941264.1
TTTTATATGCGGCCGGAGAAGCGTGTATCACCCTACCGCGTTACAGCAAATAATCCAACACAAAATTTACTATATATAAACAAATGTTTTCAACATTGAAGATTGTAACTATTCTTGCAAATTTTGATCCAATATTCCAAACATGCTAAGCAGCACGCCTCTCCCATTATCTCTCCTTCACTTCATCTTCTTGCTTCTCTCTCTAACTCTTACGTCGGCCGGTTGCCCCCAAAAATGCGGGAAATTGCAATTCTCGTATC...

CDS

1 records

下载 CDS FASTA

LOC131013199
ATGCTAAGCAGCACGCCTCTCCCATTATCTCTCCTTCACTTCATCTTCTTGCTTCTCTCTCTAACTCTTACGTCGGCCGGTTGCCCCCAAAAATGCGGGAAATTGCAATTCTCGTATCCATTCGGAGTGGGGCCAAAATGCTCCATGGATCCATCTTTCAACATCATATGCAAGAAAACCAGAAACCATTCAACACCTTACCTCAACATAAACAAAGTGCGCATGCTCGAAATCGTGGAAATAAAACAGACTCAGATACG...

Protein

1 records

下载 Protein FASTA

XP_057797247.1
MLSSTPLPLSLLHFIFLLLSLTLTSAGCPQKCGKLQFSYPFGVGPKCSMDPSFNIICKKTRNHSTPYLNINKVRMLEIVEIKQTQIRVKYPYLLAATCYTNTSVYPHNNTRDGFYSIDLTGTQYSMSDKNWLTAIGCEDIVAGFGENKNVFAGGCVSYCPTSEPHGFGSCPNTENGYSAGNGCCRTPIPKGTTFLAAQLSDLGGKWLRDKYFPCSYAFVVEKRTLDESVWLYPFSDLNKSINSQDDDWVLSGPPPVVRLD...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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