Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G004455`

染色体: Chr02 坐标: 66940716-66949432 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G004455`
名称	SmilChr02G004455
描述	wall-associated receptor kinase-like 8
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	66940716 - 66949432 / `-`

ID 对照

NCBI Gene ID	`LOC131013203`
GeneID	`131013203`
locus_tag	`-`
NCBI Name	`LOC131013203`
原始查询	`SmilChr02G004455`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	wall-associated receptor kinase-like 8
产物	wall-associated receptor kinase-like 8
Arabidopsis	`AT1G16260` (AT1G16260) Wall-associated kinase family protein [Source:NCBI gene (formerly Entrezgene);Acc:838195] identity=40.3; qcov=0.947; evalue=1.03e-155; confidence=medium
Rice	`Os04g0365100` (OsWAK37) - identity=40.4; qcov=0.94; evalue=8.52e-157; confidence=medium
GO	GO:0004674 (protein serine/threonine kinase activity); GO:0005509 (calcium ion binding); GO:0005524 (ATP binding); GO:0005886 (plasma membrane); GO:0006468 (protein phosphorylation); GO:0007166 (cell surface receptor signaling pathway); GO:0030247 (polysaccharide binding)
KEGG	-
Pfam	PF00069 (Pkinase); PF07645 (EGF_CA); PF07714 (PK_Tyr_Ser-Thr); PF12947 (EGF_3); PF13947 (GUB_WAK_bind)
InterPro	-
eggNOG	-
NR	GeneID:131013203

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057797251.1`
2	Nucleus	细胞核	0.00000	`XP_057797251.1`
3	Chromosome	染色体	0.00000	`XP_057797251.1`
4	Centromere	着丝粒	0.00000	`XP_057797251.1`
5	Chromatin	染色质	0.00000	`XP_057797251.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:66940942`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A7
`Chr2:66941509`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A19,A6,C82
`Chr2:66941681`	`C`	`CTA`	2bp_insertion	frameshift_variant	32	A2,A4,B1,B10,B101,B110,B120,B125,B135,B137,B14,B19,B4,B42,B49,B55,B58,B78,B83,B90,B92,C1,C18,C40,C44,C50,C51,C55,C57,C75,D4,D6
`Chr2:66941870`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr2:66942759`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr2:66944025`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B122,B98,C30
`Chr2:66944135`	`A`	`AT`	1bp_insertion	frameshift_variant	1	B14
`Chr2:66944135`	`A`	`AT`	1bp_insertion	CDS_variant	1	B14
`Chr2:66944271`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A3,A5,B113,C4
`Chr2:66948879`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C49
`Chr2:66948935`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B69
`Chr2:66948978`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C8

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057797251.1

771 aa

386

771

GUB_WAK_bind

EGF_CA

EGF_3

Pkinase

PK_Tyr_Ser-Thr

PF13947 GUB_WAK_bind 32-87 aa PF07645 EGF_CA 319-352 aa PF12947 EGF_3 323-356 aa PF00069 Pkinase 445-707 aa PF07714 PK_Tyr_Ser-Thr 448-708 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057797251.1`	Pfam	`PF13947`	GUB_WAK_bind	Domain	32	87	6.2e-10	40.0	Wall-associated receptor kinase galacturonan-binding
`XP_057797251.1`	Pfam	`PF07645`	EGF_CA	Domain	319	352	2.3e-12	47.6	Calcium-binding EGF domain
`XP_057797251.1`	Pfam	`PF12947`	EGF_3	Domain	323	356	2.4e-11	44.3	EGF domain
`XP_057797251.1`	Pfam	`PF00069`	Pkinase	Domain	445	707	9.8e-48	163.5	Protein kinase domain
`XP_057797251.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	448	708	4.1e-49	167.9	Protein tyrosine and serine/threonine kinase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057941268.1
GAAATACGAGATTATTAGTAATTAATTAGTATTAGCCGAGTTTTTGGGTGGCCAAAATACAAATGTTTGCTCAACTCTGGTTCATCCACTTCATCTTCTTCTCTCATCTCCTTCTCCCACTCGCAGCATTCTCCAATTCAGTAGCCAAATCCGGATGCCCGGATTCGTGCGGGGATATACCGATTCCGTTCCCATTCGGAATCGGGTCGGATTGCTCCCTCGACCCGTCTTTCAACATCTTGTGCAATACTTCTGCGGAT...

CDS

1 records

下载 CDS FASTA

LOC131013203
ATGTTTGCTCAACTCTGGTTCATCCACTTCATCTTCTTCTCTCATCTCCTTCTCCCACTCGCAGCATTCTCCAATTCAGTAGCCAAATCCGGATGCCCGGATTCGTGCGGGGATATACCGATTCCGTTCCCATTCGGAATCGGGTCGGATTGCTCCCTCGACCCGTCTTTCAACATCTTGTGCAATACTTCTGCGGATTCTACGAAACCCTACATTAAAACTCCTTCTTCTAACGTGAATCTCGAACTCGTCGAAATTAA...

Protein

1 records

下载 Protein FASTA

XP_057797251.1
MFAQLWFIHFIFFSHLLLPLAAFSNSVAKSGCPDSCGDIPIPFPFGIGSDCSLDPSFNILCNTSADSTKPYIKTPSSNVNLELVEIKEFEIRVRSPNVLNIACYDSVGKLVSSSEDYWFGIHLEGSWYTFSEENWLTAIGCDDMVLGMGGNRTFGGGCASYCVNRRDYGGLGFCPNDANGYSPGNGCCRTPIPRGLSYLGAKFIDLRQEWRRDTKLFPCSYAFVEEKVISDNSNFSYQLSYLNSSREYLNFEWGPTNTPP...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器