Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G004463`

染色体: Chr02 坐标: 67049021-67053493 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G004463`
名称	SmilChr02G004463
描述	wall-associated receptor kinase 2-like
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	67049021 - 67053493 / `-`

ID 对照

NCBI Gene ID	`LOC131007749`
GeneID	`131007749`
locus_tag	`-`
NCBI Name	`LOC131007749`
原始查询	`SmilChr02G004463`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	wall-associated receptor kinase 2-like
产物	wall-associated receptor kinase 2-like
Arabidopsis	`AT1G19390` (AT1G19390) Wall-associated kinase family protein [Source:NCBI gene (formerly Entrezgene);Acc:838522] identity=39.7; qcov=0.684; evalue=2.63e-120; confidence=medium
Rice	`Os04g0598900` (OsWAK50) - identity=39.7; qcov=0.646; evalue=5.98e-117; confidence=medium
GO	GO:0004674 (protein serine/threonine kinase activity); GO:0005509 (calcium ion binding); GO:0005524 (ATP binding); GO:0005886 (plasma membrane); GO:0006468 (protein phosphorylation); GO:0007166 (cell surface receptor signaling pathway); GO:0030247 (polysaccharide binding)
KEGG	-
Pfam	PF00069 (Pkinase); PF07645 (EGF_CA); PF07714 (PK_Tyr_Ser-Thr); PF13947 (GUB_WAK_bind)
InterPro	-
eggNOG	-
NR	GeneID:131007749

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057790635.1`
2	Nucleus	细胞核	0.00000	`XP_057790635.1`
3	Chromosome	染色体	0.00000	`XP_057790635.1`
4	Centromere	着丝粒	0.00000	`XP_057790635.1`
5	Chromatin	染色质	0.00000	`XP_057790635.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:67049777`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	C28,C74,D10
`Chr2:67049840`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B1,C8
`Chr2:67049910`	`CCA`	`C`	2bp_deletion	frameshift_variant	1	C14
`Chr2:67049910`	`CCA`	`C`	2bp_deletion	CDS_variant	1	C14
`Chr2:67049918`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B4,B73,D3
`Chr2:67049936`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B108,B50,C23
`Chr2:67049963`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B1,C8
`Chr2:67050116`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B1,C8
`Chr2:67050136`	`G`	`A`	EMS_canonical_SNV	stop_gained	74	A18,A2,A20,A23,A4,A5,B109,B11,B119,B123,B124,B125,B127,B132,B133,B135,B138,B14,B15,B17,B18,B21,B23,B24,B27,B30,B32,B33,B34,B38,B39,B42,B43,B44,B49,B51,B64,B66,B67,B7,B70,B72,B76,B77,B80,B81,B85,B87,B90,B91,B92,B95,C12,C13,C17,C20,C25,C26,C34,C37,C39,C42,C50,C51,C54,C59,C60,C72,C75,C76,C78,C81,D8,D9
`Chr2:67050227`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr2:67050236`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B1,C8
`Chr2:67050306`	`C`	`T`	EMS_canonical_SNV	stop_gained	4	A10,C2,C32,C68

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057790635.1

898 aa

449

898

GUB_WAK_bind

EGF_CA

Pkinase

PK_Tyr_Ser-Thr

PF13947 GUB_WAK_bind 31-85 aa PF13947 GUB_WAK_bind 324-378 aa PF07645 EGF_CA 608-652 aa PF00069 Pkinase 736-894 aa PF07714 PK_Tyr_Ser-Thr 739-891 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057790635.1`	Pfam	`PF13947`	GUB_WAK_bind	Domain	31	85	7.7e-20	71.8	Wall-associated receptor kinase galacturonan-binding
`XP_057790635.1`	Pfam	`PF13947`	GUB_WAK_bind	Domain	324	378	7.7e-20	71.8	Wall-associated receptor kinase galacturonan-binding
`XP_057790635.1`	Pfam	`PF07645`	EGF_CA	Domain	608	652	8.6e-11	42.6	Calcium-binding EGF domain
`XP_057790635.1`	Pfam	`PF00069`	Pkinase	Domain	736	894	2.8e-33	116.2	Protein kinase domain
`XP_057790635.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	739	891	1.4e-32	113.8	Protein tyrosine and serine/threonine kinase

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057934652.1
TCTTTTTAATATCTCCTTATATACATACTAAGTAAATAAGTGAACAACCCTTTCTCAAATATACCCATTATGCCTTGGCTACAACTAGTTTTTATCTTGTATTTCATCTTGGTGCTTCTTTTACCATCAATTTCTGCTGCTGTAATCACCAAACTTGGATGTGAGGATAAATGTGGGAATTTATCGATTCCATATCCATTTGGAGTCGGGTCGAATTGCTCGCTCGGCCCATCCTTCACGGTGAGTTGCAATACTTCCAC...

CDS

1 records

下载 CDS FASTA

LOC131007749
ATGCCTTGGCTACAACTAGTTTTTATCTTGTATTTCATCTTGGTGCTTCTTTTACCATCAATTTCTGCTGCTGTAATCACCAAACTTGGATGTGAGGATAAATGTGGGAATTTATCGATTCCATATCCATTTGGAGTCGGGTCGAATTGCTCGCTCGGCCCATCCTTCACGGTGAGTTGCAATACTTCCACAAACCCTCCAAAGGCGTATCTTTCCATCATCAATAAAGAAGTGATTGAAATAAATGAAACATATATTCG...

Protein

1 records

下载 Protein FASTA

XP_057790635.1
MPWLQLVFILYFILVLLLPSISAAVITKLGCEDKCGNLSIPYPFGVGSNCSLGPSFTVSCNTSTNPPKAYLSIINKEVIEINETYIRVKYPNLVSVCYDSSAAESSYSYKDSMAVNLTGTLYALSMYTNRLTAIGCDDAVLQSNGTSTNGGCSAFCDDDTDKGGVGYCPFDPTLLGNGCCQAQIVGDSGLVGAELIEFSRIVQRRRLFPCSYAFIQEVSDATGFSYPLYYLHNSTALHNDNWASSTSPPVVRLDWVPGAQ...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器