Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G004483`

染色体: Chr02 坐标: 67302977-67307054 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G004483`
名称	SmilChr02G004483
描述	SEC12-like protein 2
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	67302977 - 67307054 / `+`

ID 对照

NCBI Gene ID	`LOC131007764`
GeneID	`131007764`
locus_tag	`-`
NCBI Name	`LOC131007764`
原始查询	`SmilChr02G004483`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	SEC12-like protein 2
产物	SEC12-like protein 2
Arabidopsis	`AT2G01470` (STL2P) SEC12P-like 2 protein [Source:NCBI gene (formerly Entrezgene);Acc:814675] identity=46.6; qcov=1.03; evalue=1.04e-106; confidence=high
Rice	`Os11g0610700` (OsWD40-190) - identity=44.8; qcov=1.02; evalue=2.69e-106; confidence=medium
GO	GO:0003400 (GO:0003400); GO:0005085 (guanyl-nucleotide exchange factor activity); GO:0005096 (GTPase activator activity); GO:0005515 (protein binding); GO:0005789 (endoplasmic reticulum membrane); GO:0009306 (protein secretion)
KEGG	smil04141 (Protein processing in endoplasmic reticulum - Salvia miltiorrhiza (redroot sage))
Pfam	PF00400 (WD40)
InterPro	-
eggNOG	-
NR	GeneID:131007764

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Endoplasmic reticulum	内质网	1.00000	`XP_057790666.1`
2	Endoplasmic reticulum membrane	内质网膜	0.40000	`XP_057790666.1`
3	Nucleus	细胞核	0.00000	`XP_057790666.1`
4	Chromosome	染色体	0.00000	`XP_057790666.1`
5	Centromere	着丝粒	0.00000	`XP_057790666.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:67303350`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B16
`Chr2:67305254`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B56
`Chr2:67305589`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B23
`Chr2:67305629`	`A`	`AG`	1bp_insertion	frameshift_variant	57	A1,A11,A13,A22,A9,B101,B102,B105,B110,B111,B117,B122,B124,B128,B13,B131,B134,B18,B19,B21,B22,B26,B27,B29,B31,B37,B41,B5,B52,B57,B6,B60,B76,B8,B86,B88,B89,B99,C1,C16,C25,C27,C28,C35,C36,C41,C44,C50,C53,C61,C63,C75,C79,C84,D1,D2,D7
`Chr2:67305718`	`TGG`	`T`	2bp_deletion	frameshift_variant	73	A14,A18,A19,A24,A8,B105,B106,B107,B119,B12,B123,B134,B135,B136,B137,B139,B140,B16,B20,B28,B3,B30,B31,B36,B38,B39,B4,B45,B46,B48,B50,B53,B56,B57,B6,B65,B67,B69,B7,B70,B73,B79,B89,B96,B97,C13,C17,C20,C21,C27,C28,C30,C34,C36,C37,C39,C40,C43,C44,C52,C56,C57,C59,C63,C64,C66,C77,C84,C87,C9,D1,D10,D6
`Chr2:67305722`	`A`	`ACC`	2bp_insertion	frameshift_variant	59	A14,A18,A19,A8,B105,B106,B107,B119,B123,B134,B135,B136,B137,B139,B140,B16,B20,B36,B38,B39,B4,B50,B53,B56,B57,B6,B65,B67,B69,B7,B70,B78,B79,B96,B97,C13,C17,C20,C21,C28,C30,C34,C36,C37,C39,C43,C44,C52,C56,C59,C63,C64,C66,C77,C84,C87,C9,D1,D10
`Chr2:67305828`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B71,C61,C62,D5

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057790666.1

377 aa

188

377

WD40

PF00400 WD40 142-164 aa PF00400 WD40 177-198 aa PF00400 WD40 309-337 aa

XP_057790667.1

376 aa

188

376

WD40

PF00400 WD40 142-164 aa PF00400 WD40 177-198 aa PF00400 WD40 309-337 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057790666.1`	Pfam	`PF00400`	WD40	Repeat	142	164	3.8e-16	59.5	WD domain, G-beta repeat
`XP_057790666.1`	Pfam	`PF00400`	WD40	Repeat	177	198	3.8e-16	59.5	WD domain, G-beta repeat
`XP_057790666.1`	Pfam	`PF00400`	WD40	Repeat	309	337	3.8e-16	59.5	WD domain, G-beta repeat
`XP_057790667.1`	Pfam	`PF00400`	WD40	Repeat	142	164	3.9e-16	59.5	WD domain, G-beta repeat
`XP_057790667.1`	Pfam	`PF00400`	WD40	Repeat	177	198	3.9e-16	59.5	WD domain, G-beta repeat
`XP_057790667.1`	Pfam	`PF00400`	WD40	Repeat	309	337	3.9e-16	59.5	WD domain, G-beta repeat

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057934683.1
ATATTTTCATAGAGACATCTTTTGTTATACATATCTTCTATAATCTTTTTATTATACATATCTTCTATAATCATTATCTTTTGTTATACATATCTTCTATAATCTTTTTATAAATAAACATTTAAATCCTAACCCTTATTTTTGTATCTTTTTATAAATAGAGACATTTGATTCTGAAAGCGTTGTATATTTTCACACGTTCCTCACAAAAACACACGTTCCTGTATATTTTCTACGACTACGTTGTATCACATTCACAG...

XM_057934684.1
CATAGAGACATCTTTTGTTATACATATCTTCTATAATCTTTTTATTATACATATCTTCTATAATCATTATCTTTTGTTATACATATCTTCTATAATCTTTTTATAAATAAACATTTAAATCCTAACCCTTATTTTTGTATCTTTTTATAAATAGAGACATTTGATTCTGAAAGCGTTGTATATTTTCACACGTTCCTCACAAAAACACACGTTCCTGTATATTTTCTACGACTACGTTGTATCACATTCACAGCGGAGCA...

CDS

2 records

下载 CDS FASTA

LOC131007764
ATGGAAAACGATGAAGCATTGAGCTGCAAGAAGTATGGAGTCCCACTGTACGCCGCCGCCTGGGTTCCATCTGCCGCCGGTAGATTAGATACCGCCAAAGAGTTGGAAACTCCTGCCAAACCCCTCGTTGTCCTAGCCGGAGGCGGCGGAAAAGGCAACACCGGAATACCAAATGCCATCCTCCTCTCGGCCTTTGATTCCGAATCCTGCTCCCTCTCTGATCAGCCTGTGGCTAAGCTGGGAACTGGTAGCGATCTGCC...

Protein

2 records

下载 Protein FASTA

XP_057790666.1
MENDEALSCKKYGVPLYAAAWVPSAAGRLDTAKELETPAKPLVVLAGGGGKGNTGIPNAILLSAFDSESCSLSDQPVAKLGTGSDLPYRIGVHPGGEGIICSFCPQNCRWFEWDSNTDDQTLRLKSSEKVLKPLEDVGLQLALTFNTEGNLLAVGGEDGQLRVFKWPAMESILSEANAHSSVGDLDFSPDGKFLVSVGGGPGRIWDVASSSSVVSLPKENDEIFSFCRFSRSTGTDQVLYITTNRDKGGSIVKWNPTSWE...

XP_057790667.1
MENDEALSCKKYGVPLYAAAWVPSAAGRLDTAKELETPAKPLVVLAGGGGKGNTGIPNAILLSAFDSESCSLSDQPVAKLGTGSDLPYRIGVHPGGEGIICSFCPQNCRWFEWDSNTDDQTLRLKSSEKVLKPLEDVGLQLALTFNTEGNLLAVGGEDGQLRVFKWPAMESILSEANAHSSVGDLDFSPDGKFLVSVGGGPGRIWDVASSSSVVSLPKENDEIFSFCRFSRSTGTDQVLYITTNRDKGGSIVKWNPTSWE...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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