Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G004502`

染色体: Chr02 坐标: 67528523-67540445 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G004502`
名称	SmilChr02G004502
描述	vacuolar sorting protein 18
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	67528523 - 67540445 / `-`

ID 对照

NCBI Gene ID	`LOC131011168`
GeneID	`131011168`
locus_tag	`-`
NCBI Name	`LOC131011168`
原始查询	`SmilChr02G004502`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	vacuolar sorting protein 18
产物	vacuolar sorting protein 18
Arabidopsis	`AT1G12470` (AT1G12470) zinc ion binding protein [Source:NCBI gene (formerly Entrezgene);Acc:837804] identity=78.6; qcov=1; evalue=0; confidence=high
Rice	`Os08g0178100` - identity=72.7; qcov=0.993; evalue=0; confidence=high
GO	GO:0005768 (endosome); GO:0006886 (intracellular protein transport); GO:0006904 (GO:0006904); GO:0007032 (endosome organization); GO:0007033 (vacuole organization); GO:0016192 (vesicle-mediated transport); GO:0030674 (protein-macromolecule adaptor activity); GO:0030897 (HOPS complex); GO:0048284 (organelle fusion)
KEGG	smil04142 (Lysosome biogenesis - Salvia miltiorrhiza (redroot sage)); smil04145 (Phagocytosis - Salvia miltiorrhiza (redroot sage)); smil04148 (Efferocytosis - Salvia miltiorrhiza (redroot sage))
Pfam	PF00637 (Clathrin); PF05131 (Pep3_Vps18); PF26148 (VPS18_RING_C); PF28736 (VPS18_solenoid_1st); PF28737 (VPS18_solenoid_2nd)
InterPro	-
eggNOG	-
NR	GeneID:131011168

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Golgi apparatus	高尔基体	0.80000	`XP_057794948.1`
2	Trans-golgi network	Trans-golgi network	0.80000	`XP_057794948.1`
3	Cytoplasmic vesicle	细胞质囊泡	0.60000	`XP_057794948.1`
4	Endocytic vesicle	Endocytic vesicle	0.60000	`XP_057794948.1`
5	Cytosol	细胞质基质	0.60000	`XP_057794948.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:67528867`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr2:67528966`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B42,B43,C24,C26,C83
`Chr2:67529387`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A18
`Chr2:67537130`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A18
`Chr2:67538125`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B16
`Chr2:67538134`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C64,C66
`Chr2:67539151`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B37
`Chr2:67539960`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A21
`Chr2:67539962`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C14
`Chr2:67540103`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B139,B16,D1

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057794948.1

985 aa

492

985

Pep3_Vps18

VPS18_solenoid_1st

VPS18_solenoid_2nd

Clathrin

VPS18_RING_C

PF05131 Pep3_Vps18 14-359 aa PF28736 VPS18_solenoid_1st 374-534 aa PF28737 VPS18_solenoid_2nd 537-740 aa PF00637 Clathrin 610-743 aa PF26148 VPS18_RING_C 864-952 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057794948.1`	Pfam	`PF05131`	Pep3_Vps18	Repeat	14	359	4.2e-83	280.0	Pep3/Vps18/deep orange beta-propeller domain
`XP_057794948.1`	Pfam	`PF28736`	VPS18_solenoid_1st	Repeat	374	534	1.8e-36	126.4	VPS18, alpha-solenoid domain, first half
`XP_057794948.1`	Pfam	`PF28737`	VPS18_solenoid_2nd	Repeat	537	740	6.3e-63	213.0	VPS18, alpha-solenoid domain, second half
`XP_057794948.1`	Pfam	`PF00637`	Clathrin	Repeat	610	743	3e-08	34.2	Region in Clathrin and VPS
`XP_057794948.1`	Pfam	`PF26148`	VPS18_RING_C	Domain	864	952	1.6e-06	28.8	VPS18 RING C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057938965.1
TTTATCCATACATTATATCACTAGTTTAGGCTAAAAAAGCATATCAAATTATTTTCATGTATTTTTTAGTTCAACTTATATAATCATAATTCGAATTTAACACAAACAGAATCTTACAAAAACCATATTTATATAAACAATATCAATTTTGTATGTGAGATTTATAAGAAACGCATCAATTTCGTCTTCATTGAAACAAATTTAGCTAAGCTGAATATCAAATCGTCAAAATCCCCACGATCGTGACCCGGAATTTCAAT...

CDS

1 records

下载 CDS FASTA

LOC131011168
ATGGAGTCGCTGCGGCAGGTGTTCTCGGTGGACGTACTGGAGAGGTATGCCGCTAAGGGGCGGGGAGTGATTACGTGTTTGGCCACCGGAAATGACGTCATTGTGCTCGGAACCAGCAAGGGTTGGGTCATCCGCCATGATTTCGGCGTCGGGGATTCATTTGATATTGATCTCTCTGTCGGAAGACCTGGTGAGCAGTCAATCTATAGGGTTTTTGTTGATCCTGGAGGTAGCCATTGTATTGCTACTGTTGTTGGCGG...

Protein

1 records

下载 Protein FASTA

XP_057794948.1
MESLRQVFSVDVLERYAAKGRGVITCLATGNDVIVLGTSKGWVIRHDFGVGDSFDIDLSVGRPGEQSIYRVFVDPGGSHCIATVVGGGTSDTFYTHAKWAKPRILSRLKGLLVNTVAWNRQHITEAYTKEIILGTENGQLYEVSVDEKDKKEKYIKFLFELNELPEEFTGLQMETTGTNTGIRYYVMAVTPTRLYSFTGIGSLETVFVSYADRAVHFMELPGEIPNSELHFFIKQRRAVHFAWLSGAGIYHGDLNFGAHH...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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