Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G004846`

染色体: Chr02 坐标: 70604485-70608280 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G004846`
名称	SmilChr02G004846
描述	chaperone protein ClpB1
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	70604485 - 70608280 / `+`

ID 对照

NCBI Gene ID	`LOC131008843`
GeneID	`131008843`
locus_tag	`-`
NCBI Name	`LOC131008843`
原始查询	`SmilChr02G004846`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	chaperone protein ClpB1
产物	chaperone protein ClpB1
Arabidopsis	`AT1G74310` (HSP101) heat shock protein 101 [Source:NCBI gene (formerly Entrezgene);Acc:843771] identity=85.3; qcov=0.99; evalue=0; confidence=high
Rice	`Os05g0519700` (HSP101) - identity=83; qcov=0.997; evalue=0; confidence=high
GO	GO:0005524 (ATP binding); GO:0005737 (cytoplasm); GO:0016887 (ATP hydrolysis activity); GO:0034605 (cellular response to heat)
KEGG	-
Pfam	PF00004 (AAA); PF00158 (Sigma54_activat); PF02861 (Clp_N); PF07724 (AAA_2); PF07728 (AAA_5); PF10431 (ClpB_D2-small); PF13401 (AAA_22); PF17871 (AAA_lid_9); PF23569 (NBD_SMAX1)
InterPro	-
eggNOG	-
NR	GeneID:131008843

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057791906.1`
2	Cytosol	细胞质基质	1.00000	`XP_057791906.1`
3	Nucleus	细胞核	0.20000	`XP_057791906.1`
4	Chromosome	染色体	0.00000	`XP_057791906.1`
5	Centromere	着丝粒	0.00000	`XP_057791906.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:70605112`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B113
`Chr2:70605115`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B21
`Chr2:70605200`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B133,B41,B73,C17
`Chr2:70605343`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B131,C33,C37
`Chr2:70605377`	`C`	`T`	EMS_canonical_SNV	stop_gained	1	D11
`Chr2:70605377`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr2:70605400`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B59,B7,B80,B95,C47
`Chr2:70605771`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C85
`Chr2:70605814`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B80
`Chr2:70605910`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B2,B20,B48,C20,D5
`Chr2:70605958`	`AC`	`A`	1bp_deletion	frameshift_variant	1	B92
`Chr2:70605958`	`AC`	`A`	1bp_deletion	CDS_variant	1	B92

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057791906.1

910 aa

455

910

Clp_N

NBD_SMAX1

AAA

AAA_lid_9

AAA_2

AAA_22

Sigma54_activat

AAA_5

AAA

ClpB_D2-small

PF02861 Clp_N 5-130 aa PF23569 NBD_SMAX1 186-286 aa PF00004 AAA 205-318 aa PF17871 AAA_lid_9 345-445 aa PF07724 AAA_2 598-762 aa PF13401 AAA_22 600-697 aa PF00158 Sigma54_activat 601-718 aa PF07728 AAA_5 602-721 aa PF00004 AAA 603-720 aa PF10431 ClpB_D2-small 768-847 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057791906.1`	Pfam	`PF02861`	Clp_N	Family	5	130	9.5e-29	100.9	Clp repeat (R) N-terminal domain
`XP_057791906.1`	Pfam	`PF23569`	NBD_SMAX1	Domain	186	286	7.2e-10	39.8	SMAX1 nucleotide binding domain
`XP_057791906.1`	Pfam	`PF00004`	AAA	Domain	205	318	1.7e-25	90.7	ATPase family associated with various cellular activities (AAA)
`XP_057791906.1`	Pfam	`PF17871`	AAA_lid_9	Domain	345	445	3.4e-34	117.6	AAA lid domain
`XP_057791906.1`	Pfam	`PF07724`	AAA_2	Domain	598	762	6.8e-71	238.4	AAA domain (Cdc48 subfamily)
`XP_057791906.1`	Pfam	`PF13401`	AAA_22	Domain	600	697	2.2e-13	51.4	AAA domain
`XP_057791906.1`	Pfam	`PF00158`	Sigma54_activat	Domain	601	718	3.9e-09	37.1	Sigma-54 interaction domain
`XP_057791906.1`	Pfam	`PF07728`	AAA_5	Domain	602	721	5e-17	62.9	AAA domain (dynein-related subfamily)
`XP_057791906.1`	Pfam	`PF00004`	AAA	Domain	603	720	1.7e-25	90.7	ATPase family associated with various cellular activities (AAA)
`XP_057791906.1`	Pfam	`PF10431`	ClpB_D2-small	Domain	768	847	7e-22	78.0	C-terminal, D2-small domain, of ClpB protein

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057935923.1
AGGCTTTCCAATTCCAGATATTTCTCTTGCCTTATCAAAACCGACGCTTCACTTTCAACACACACATCAATCATCACACAGCATACATCACATTCTTTAGCAAAAACAAATTATCTTTCGACGCAAAATTCCTTGAATACGAAATCGTACTGAGCGTTGGCCAGTGTTCTTGCAGAATTTTCCGATTAAGAATATAATCCAGTGATGAATCCCGAAAAATTCACCCACAAGACAAATGAAACCCTCGCCGCGGCCCACGA...

CDS

1 records

下载 CDS FASTA

LOC131008843
ATGAATCCCGAAAAATTCACCCACAAGACAAATGAAACCCTCGCCGCGGCCCACGAGCTCGCAATGAGCTCCGGCCACGCCCAATTCACTCCTCTACACTTCGCATCAGCTTTAATGTCCGATGCAAACGGCATTTTCCGGCAGGCGGTGGCCGGCGCCGGCGCCGGCGAAGATTCCGTGAATGCGGTGGAAAGGGTGATCAAGCAAGCCATGAAGAAGATCCCCTCGCAGACGCCGCCTCCTGACGAGATCCCCGCCAG...

Protein

1 records

下载 Protein FASTA

XP_057791906.1
MNPEKFTHKTNETLAAAHELAMSSGHAQFTPLHFASALMSDANGIFRQAVAGAGAGEDSVNAVERVIKQAMKKIPSQTPPPDEIPASTSLIKVIRRAQSLQKSRGDTHLAVDQLILGLLEDSQIQDLLKEAGVHAAKVKSEVEKLRGKEGRKVESASGDTTFQALKTYGRDLVEQAGKLDPVIGRDEEIRRVVRILSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVAGDVPSNLADVRLIALDMGALIAGAKYRGEFEER...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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