Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G004878`

染色体: Chr02 坐标: 70870364-70874927 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G004878`
名称	SmilChr02G004878
描述	calcium-dependent protein kinase 10-like
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	70870364 - 70874927 / `+`

ID 对照

NCBI Gene ID	`LOC131008876`
GeneID	`131008876`
locus_tag	`-`
NCBI Name	`LOC131008876`
原始查询	`SmilChr02G004878`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	calcium-dependent protein kinase 10-like
产物	calcium-dependent protein kinase 10-like
Arabidopsis	`AT1G74740` (CPK30) calcium-dependent protein kinase 30 [Source:NCBI gene (formerly Entrezgene);Acc:843813] identity=78.5; qcov=1.01; evalue=0; confidence=high
Rice	`Os01g0832300` (OsCDPK3) - identity=75.8; qcov=0.877; evalue=0; confidence=high
GO	GO:0004683 (calcium/calmodulin-dependent protein kinase activity); GO:0005509 (calcium ion binding); GO:0005516 (calmodulin binding); GO:0005524 (ATP binding); GO:0005634 (nucleus); GO:0005737 (cytoplasm); GO:0009931 (calcium-dependent protein serine/threonine kinase activity); GO:0018105 (peptidyl-serine phosphorylation); GO:0035556 (intracellular signal transduction); GO:0046777 (protein autophosphorylation)
KEGG	smil04075 (Plant hormone signal transduction - Salvia miltiorrhiza (redroot sage)); smil04626 (Plant-pathogen interaction - Salvia miltiorrhiza (redroot sage))
Pfam	PF00036 (EF-hand_1); PF00069 (Pkinase); PF03109 (ABC1); PF06293 (Kdo); PF07714 (PK_Tyr_Ser-Thr); PF13202 (EF-hand_5); PF13405 (EF-hand_6); PF13499 (EF-hand_7); PF13833 (EF-hand_8)
InterPro	-
eggNOG	-
NR	GeneID:131008876

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057791956.1`
2	Cytosol	细胞质基质	0.60000	`XP_057791956.1`
3	Cytoplasm	细胞质	0.20000	`XP_057791956.1`
4	Nucleus	细胞核	0.00000	`XP_057791956.1`
5	Chromosome	染色体	0.00000	`XP_057791956.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:70870767`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C47,C49
`Chr2:70870803`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C47,C49
`Chr2:70870884`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B36,C1,C16,C41
`Chr2:70871082`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B140,B57,B63
`Chr2:70871103`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B140,B57,B63
`Chr2:70871205`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B91,C35,C4
`Chr2:70871532`	`T`	`TA`	1bp_insertion	frameshift_variant	8	A2,B109,B114,B122,B127,B94,C82,D11
`Chr2:70871565`	`GT`	`G`	1bp_deletion	frameshift_variant	178	A1,A10,A11,A13,A14,A15,A18,A19,A20,A21,A22,A23,A24,A25,A3,A4,A6,A8,A9,B10,B101,B102,B103,B104,B108,B11,B111,B112,B115,B117,B118,B119,B12,B120,B121,B122,B124,B125,B126,B129,B13,B137,B138,B139,B14,B140,B15,B18,B20,B25,B26,B29,B3,B30,B31,B33,B34,B35,B36,B38,B39,B4,B41,B44,B45,B46,B47,B48,B5,B51,B52,B53,B54,B55,B57,B58,B59,B60,B61,B62,B63,B64,B65,B67,B68,B7,B71,B72,B73,B74,B75,B76,B77,B78,B79,B8,B80,B81,B83,B85,B90,B91,B92,B93,B95,B97,B98,C1,C10,C12,C13,C14,C16,C17,C18,C19,C2,C20,C22,C24,C27,C3,C30,C31,C32,C33,C35,C37,C39,C4,C40,C42,C43,C44,C45,C47,C48,C49,C5,C50,C51,C52,C53,C54,C56,C57,C58,C59,C6,C60,C61,C62,C65,C67,C68,C7,C71,C72,C74,C75,C76,C78,C8,C80,C81,C83,C84,C85,C87,C9,D1,D11,D2,D3,D4,D5,D7,D8
`Chr2:70871579`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B104,C47,C49
`Chr2:70871647`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr2:70871683`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B140,B57,B63,C47,C49
`Chr2:70873870`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C47,C49

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057791956.1

567 aa

284

567

Pkinase

PK_Tyr_Ser-Thr

Kdo

ABC1

EF-hand_8

EF-hand_5

EF-hand_1

EF-hand_6

EF-hand_7

EF-hand_8

EF-hand_7

EF-hand_1

EF-hand_6

EF-hand_5

EF-hand_8

EF-hand_5

EF-hand_1

PF00069 Pkinase 61-343 aa PF07714 PK_Tyr_Ser-Thr 63-261 aa PF06293 Kdo 78-208 aa PF03109 ABC1 132-217 aa PF13833 EF-hand_8 376-412 aa PF13202 EF-hand_5 391-413 aa PF00036 EF-hand_1 391-417 aa PF13405 EF-hand_6 391-419 aa PF13499 EF-hand_7 391-450 aa PF13833 EF-hand_8 404-450 aa PF13499 EF-hand_7 461-524 aa PF00036 EF-hand_1 463-485 aa PF13405 EF-hand_6 463-485 aa PF13202 EF-hand_5 464-485 aa PF13833 EF-hand_8 497-524 aa PF13202 EF-hand_5 499-523 aa PF00036 EF-hand_1 499-525 aa

XP_057791958.1

543 aa

272

543

Pkinase

PK_Tyr_Ser-Thr

Kdo

ABC1

EF-hand_8

EF-hand_5

EF-hand_1

EF-hand_6

EF-hand_7

EF-hand_8

EF-hand_7

EF-hand_1

EF-hand_6

EF-hand_5

EF-hand_8

EF-hand_5

EF-hand_1

PF00069 Pkinase 61-319 aa PF07714 PK_Tyr_Ser-Thr 63-314 aa PF06293 Kdo 77-208 aa PF03109 ABC1 132-217 aa PF13833 EF-hand_8 352-388 aa PF13202 EF-hand_5 367-389 aa PF00036 EF-hand_1 367-393 aa PF13405 EF-hand_6 367-395 aa PF13499 EF-hand_7 367-426 aa PF13833 EF-hand_8 380-426 aa PF13499 EF-hand_7 437-500 aa PF00036 EF-hand_1 439-461 aa PF13405 EF-hand_6 439-461 aa PF13202 EF-hand_5 440-461 aa PF13833 EF-hand_8 473-500 aa PF13202 EF-hand_5 475-499 aa PF00036 EF-hand_1 475-501 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057791956.1`	Pfam	`PF00069`	Pkinase	Domain	61	343	8.3e-75	252.3	Protein kinase domain
`XP_057791956.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	63	261	1.8e-25	90.4	Protein tyrosine and serine/threonine kinase
`XP_057791956.1`	Pfam	`PF06293`	Kdo	Family	78	208	2.4e-08	34.4	Lipopolysaccharide kinase (Kdo/WaaP) family
`XP_057791956.1`	Pfam	`PF03109`	ABC1	Domain	132	217	5.7e-06	26.4	ABC1 atypical kinase-like domain
`XP_057791956.1`	Pfam	`PF13833`	EF-hand_8	Domain	376	412	1.4e-17	63.9	EF-hand domain pair
`XP_057791956.1`	Pfam	`PF13202`	EF-hand_5	Domain	391	413	8.7e-22	76.3	EF hand
`XP_057791956.1`	Pfam	`PF00036`	EF-hand_1	Domain	391	417	1.5e-29	100.0	EF hand domain
`XP_057791956.1`	Pfam	`PF13405`	EF-hand_6	Domain	391	419	2.5e-23	80.2	EF-hand domain
`XP_057791956.1`	Pfam	`PF13499`	EF-hand_7	Domain	391	450	2.8e-28	98.8	EF-hand domain pair
`XP_057791956.1`	Pfam	`PF13833`	EF-hand_8	Domain	404	450	1.4e-17	63.9	EF-hand domain pair
`XP_057791956.1`	Pfam	`PF13499`	EF-hand_7	Domain	461	524	2.8e-28	98.8	EF-hand domain pair
`XP_057791956.1`	Pfam	`PF00036`	EF-hand_1	Domain	463	485	1.5e-29	100.0	EF hand domain
`XP_057791956.1`	Pfam	`PF13405`	EF-hand_6	Domain	463	485	2.5e-23	80.2	EF-hand domain
`XP_057791956.1`	Pfam	`PF13202`	EF-hand_5	Domain	464	485	8.7e-22	76.3	EF hand
`XP_057791956.1`	Pfam	`PF13833`	EF-hand_8	Domain	497	524	1.4e-17	63.9	EF-hand domain pair
`XP_057791956.1`	Pfam	`PF13202`	EF-hand_5	Domain	499	523	8.7e-22	76.3	EF hand
`XP_057791956.1`	Pfam	`PF00036`	EF-hand_1	Domain	499	525	1.5e-29	100.0	EF hand domain
`XP_057791958.1`	Pfam	`PF00069`	Pkinase	Domain	61	319	2.2e-77	260.7	Protein kinase domain
`XP_057791958.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	63	314	1.4e-27	97.3	Protein tyrosine and serine/threonine kinase
`XP_057791958.1`	Pfam	`PF06293`	Kdo	Family	77	208	2.3e-08	34.5	Lipopolysaccharide kinase (Kdo/WaaP) family
`XP_057791958.1`	Pfam	`PF03109`	ABC1	Domain	132	217	5.5e-06	26.4	ABC1 atypical kinase-like domain
`XP_057791958.1`	Pfam	`PF13833`	EF-hand_8	Domain	352	388	1.2e-17	64.1	EF-hand domain pair
`XP_057791958.1`	Pfam	`PF13202`	EF-hand_5	Domain	367	389	7.1e-22	76.5	EF hand
`XP_057791958.1`	Pfam	`PF00036`	EF-hand_1	Domain	367	393	1.3e-29	100.3	EF hand domain
`XP_057791958.1`	Pfam	`PF13405`	EF-hand_6	Domain	367	395	2e-23	80.5	EF-hand domain
`XP_057791958.1`	Pfam	`PF13499`	EF-hand_7	Domain	367	426	2.5e-28	99.0	EF-hand domain pair
`XP_057791958.1`	Pfam	`PF13833`	EF-hand_8	Domain	380	426	1.2e-17	64.1	EF-hand domain pair
`XP_057791958.1`	Pfam	`PF13499`	EF-hand_7	Domain	437	500	2.5e-28	99.0	EF-hand domain pair
`XP_057791958.1`	Pfam	`PF00036`	EF-hand_1	Domain	439	461	1.3e-29	100.3	EF hand domain
`XP_057791958.1`	Pfam	`PF13405`	EF-hand_6	Domain	439	461	2e-23	80.5	EF-hand domain
`XP_057791958.1`	Pfam	`PF13202`	EF-hand_5	Domain	440	461	7.1e-22	76.5	EF hand
`XP_057791958.1`	Pfam	`PF13833`	EF-hand_8	Domain	473	500	1.2e-17	64.1	EF-hand domain pair
`XP_057791958.1`	Pfam	`PF13202`	EF-hand_5	Domain	475	499	7.1e-22	76.5	EF hand
`XP_057791958.1`	Pfam	`PF00036`	EF-hand_1	Domain	475	501	1.3e-29	100.3	EF hand domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057935975.1
AAAAAGAAGAAGATAGTTTTCCGATTTAAATGTGAAACGAGATTAGAACGCAAAATACGCCAAAAGAAACACAATATTTAAATATTAAACATTATAAAAACTCCTTTTTCAAACACTAAAACTTTTCCTCCAAAATTGACCCCGCGTTTTCTCTCTCTTACTAAACTATCTTCTTCTTCTTCTTCCTCCTCCTCCCCATCGTTCTCCACCACCACCACCACCACTGACGGCGGCGCTGTCACTTTTCCTAGCTGCTGAAA...

XM_057935973.1
TTTTCAAACACTAAAACTTTTCCTCCAAAATTGACCCCGCGTTTTCTCTCTCTTACTAAACTATCTTCTTCTTCTTCTTCCTCCTCCTCCCCATCGTTCTCCACCACCACCACCACCACTGACGGCGGCGCTGTCACTTTTCCTAGCTGCTGAAATCTCAACTATCCTCTATGGGAAATTGCAACGCGTGCATCCGACCTCCTGAAAAGGAGTCCCCAAATTCAAAACCACAAACCCCCAAACCCCGCAAAAACAACCGC...

CDS

2 records

下载 CDS FASTA

LOC131008876
ATGGGAAATTGCAACGCGTGCATCCGACCTCCTGAAAAGGAGTCCCCAAATTCAAAACCACAAACCCCCAAACCCCGCAAAAACAACCGCGGCGAGCACGTCCCCAATCCCTACGCCCGATCTCCCGCCCCGATCCGCGTGCTGAAGGACTTCATGCCGCGCACGCGGATCTCCGACAAGTACGTCCTCGGGCGCGAGCTCGGCCGCGGCGAGTTCGGCGTCACCTACCTCTGCACCGACCGCGAGACGCGGGAGGCGCT...

Protein

2 records

下载 Protein FASTA

XP_057791956.1
MGNCNACIRPPEKESPNSKPQTPKPRKNNRGEHVPNPYARSPAPIRVLKDFMPRTRISDKYVLGRELGRGEFGVTYLCTDRETREALACKSISKKKLRTAVDVEDVRREVAIMSSLPEHANIVKMRAAYEDSEAVHLVMELCEGGELFDRIVARGHYSERAAAGVAKTVAEVVRMCHQHGVMHRDLKPENFLFANKKENSALKVIDFGLSVFFKPGERFSEIVGSPYYMAPEVLKRNYGPEVDIWSAGVILYILLCGVPP...

XP_057791958.1
MGNCNACIRPPEKESPNSKPQTPKPRKNNRGEHVPNPYARSPAPIRVLKDFMPRTRISDKYVLGRELGRGEFGVTYLCTDRETREALACKSISKKKLRTAVDVEDVRREVAIMSSLPEHANIVKMRAAYEDSEAVHLVMELCEGGELFDRIVARGHYSERAAAGVAKTVAEVVRMCHQHGVMHRDLKPENFLFANKKENSALKVIDFGLSVFFKPGERFSEIVGSPYYMAPEVLKRNYGPEVDIWSAGVILYILLCGVPP...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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