Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G005367`

染色体: Chr02 坐标: 74359181-74365615 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G005367`
名称	SmilChr02G005367
描述	aconitate hydratase, cytoplasmic
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	74359181 - 74365615 / `-`

ID 对照

NCBI Gene ID	`LOC131009346`
GeneID	`131009346`
locus_tag	`-`
NCBI Name	`LOC131009346`
原始查询	`SmilChr02G005367`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	aconitate hydratase, cytoplasmic
产物	aconitate hydratase%2C cytoplasmic
Arabidopsis	`AT2G05710` (ACO3) aconitase 3 [Source:NCBI gene (formerly Entrezgene);Acc:815120] identity=86.9; qcov=0.95; evalue=0; confidence=high
Rice	`Os08g0191100` (OsACO1) - identity=84; qcov=0.943; evalue=0; confidence=high
GO	GO:0003994 (aconitate hydratase activity); GO:0005739 (mitochondrion); GO:0005829 (cytosol); GO:0006099 (tricarboxylic acid cycle); GO:0006101 (citrate metabolic process); GO:0051539 (4 iron, 4 sulfur cluster binding)
KEGG	smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil00630 (Glyoxylate and dicarboxylate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF00330 (Aconitase); PF00694 (Aconitase_C)
InterPro	-
eggNOG	-
NR	GeneID:131009346

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057792625.1`
2	Mitochondrion matrix	线粒体基质	0.80000	`XP_057792625.1`
3	Nucleus	细胞核	0.00000	`XP_057792625.1`
4	Chromosome	染色体	0.00000	`XP_057792625.1`
5	Centromere	着丝粒	0.00000	`XP_057792625.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:74359634`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C82
`Chr2:74359650`	`A`	`AC`	1bp_insertion	frameshift_variant	5	B2,B78,C14,C18,D7
`Chr2:74359650`	`A`	`AC`	1bp_insertion	CDS_variant	5	B2,B78,C14,C18,D7
`Chr2:74359669`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B101,B107,B115,C45
`Chr2:74359678`	`A`	`AT`	1bp_insertion	frameshift_variant	106	A1,A10,A14,A15,A16,A2,A21,A25,A5,A6,A7,B102,B104,B108,B110,B113,B114,B115,B117,B118,B119,B12,B121,B123,B124,B127,B129,B131,B136,B137,B138,B14,B17,B18,B20,B23,B24,B25,B28,B30,B31,B33,B36,B37,B42,B43,B49,B51,B52,B55,B57,B60,B61,B64,B66,B7,B72,B76,B79,B81,B82,B85,B86,B87,B89,B9,B90,B92,B94,B98,B99,C1,C10,C11,C12,C15,C16,C20,C23,C27,C34,C35,C41,C42,C43,C51,C53,C54,C58,C6,C69,C70,C78,C8,C80,C82,C83,C84,C85,C86,C9,D10,D4,D5,D6,D8
`Chr2:74359704`	`T`	`TA`	1bp_insertion	frameshift_variant	27	A1,A10,A16,A21,A5,A7,B108,B114,B115,B119,B129,B18,B23,B49,B57,B61,B64,B89,C10,C11,C12,C34,C42,C69,C78,C83,C84
`Chr2:74359741`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	C2,C32,C68
`Chr2:74360059`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C38,C79
`Chr2:74360074`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	C38,C79,D11
`Chr2:74360116`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B49,B60
`Chr2:74360139`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B50
`Chr2:74360263`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B101,B140

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057792625.1

1015 aa

508

1015

Aconitase

Aconitase_C

PF00330 Aconitase 163-665 aa PF00694 Aconitase_C 794-922 aa

XP_057792626.1

995 aa

498

995

Aconitase

Aconitase_C

PF00330 Aconitase 163-665 aa PF00694 Aconitase_C 794-922 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057792625.1`	Pfam	`PF00330`	Aconitase	Family	163	665	8.8e-169	563.0	Aconitase family (aconitate hydratase)
`XP_057792625.1`	Pfam	`PF00694`	Aconitase_C	Domain	794	922	6.1e-41	140.5	Aconitase C-terminal domain
`XP_057792626.1`	Pfam	`PF00330`	Aconitase	Family	163	665	8.3e-169	563.1	Aconitase family (aconitate hydratase)
`XP_057792626.1`	Pfam	`PF00694`	Aconitase_C	Domain	794	922	6e-41	140.6	Aconitase C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057936643.1
GTGCCCTTCCCGAATGGGCCGTGTCCAAATTTCCCACAAAAGCATATAAAAAGCGAAGAAAAAATCAAAGTCGTCTCATCATCTCTCATGTGCCCCCCACAAGCATTCAACCCTCTTCCCATAAAATCTCATCTCCGTCAATTCCTCTGATTTCTCCTCATATATATTCACCATTTCTTCATCCTCAGGCACGCACTTCGATTCCACCTCTCAATCCCCATACCGATCCTTATCCCTGCGCCGATTTTCTGTTTCGGTTT...

XM_057936642.1
GTGCCCTTCCCGAATGGGCCGTGTCCAAATTTCCCACAAAAGCATATAAAAAGCGAAGAAAAAATCAAAGTCGTCTCATCATCTCTCATGTGCCCCCCACAAGCATTCAACCCTCTTCCCATAAAATCTCATCTCCGTCAATTCCTCTGATTTCTCCTCATATATATTCACCATTTCTTCATCCTCAGGCACGCACTTCGATTCCACCTCTCAATCCCCATACCGATCCTTATCCCTGCGCCGATTTTCTGTTTCGGTTT...

CDS

2 records

下载 CDS FASTA

LOC131009346
ATGTATATAACCAGCGGCACCTCGGCTCTCCTAAAGAGGGCTTCTCACTCCTCCTCCACCAGAAGAGCCTTCTCCTCTTCTCTCTCTAGGAAACCAGCCGCGCCTCCGCGTCCCTCCGCTGGTAGCCCGCAGTCGCCGGGGCAGCAGAATCTCCGATCTCTGAGCTATTTGTCGTCGGCGGCGGCGAGGTGGAGCCACGGCGTTGGTTGGAACTCCCCCACCAGTGCCGCGTCGCAGATCAGGATCGCTGCTTTGGCGTC...

Protein

2 records

下载 Protein FASTA

XP_057792625.1
MYITSGTSALLKRASHSSSTRRAFSSSLSRKPAAPPRPSAGSPQSPGQQNLRSLSYLSSAAARWSHGVGWNSPTSAASQIRIAALASDSLLHRKIATMASENAFKGIFTSLPKPGGGEFGKFYSLPALNDPRIDKLPYSIRILLESAIRNCDGFQVTKEDVEKIIDWEKTSPKLVEIPFKPARVLLQDFTGVPAVVDLACMRDAMNRLGSDSDKINPLVPVDLVIDHSVQVDVARSENAVQANMELEFQRNRERFAFLKW...

XP_057792626.1
MYITSGTSALLKRASHSSSTRRAFSSSLSRKPAAPPRPSAGSPQSPGQQNLRSLSYLSSAAARWSHGVGWNSPTSAASQIRIAALASDSLLHRKIATMASENAFKGIFTSLPKPGGGEFGKFYSLPALNDPRIDKLPYSIRILLESAIRNCDGFQVTKEDVEKIIDWEKTSPKLVEIPFKPARVLLQDFTGVPAVVDLACMRDAMNRLGSDSDKINPLVPVDLVIDHSVQVDVARSENAVQANMELEFQRNRERFAFLKW...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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