Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G005466`

染色体: Chr02 坐标: 74949562-74959898 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G005466`
名称	SmilChr02G005466
描述	histone acetyltransferase HAC1-like
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	74949562 - 74959898 / `+`

ID 对照

NCBI Gene ID	`LOC131009428`
GeneID	`131009428`
locus_tag	`-`
NCBI Name	`LOC131009428`
原始查询	`SmilChr02G005466`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	histone acetyltransferase HAC1-like
产物	histone acetyltransferase HAC1-like
Arabidopsis	`AT1G79000` (HAC1) histone acetyltransferase of the CBP family 1 [Source:NCBI gene (formerly Entrezgene);Acc:844241] identity=56.6; qcov=1.03; evalue=0; confidence=high
Rice	`Os02g0137500` (OsHAC703) - identity=80.8; qcov=0.365; evalue=0; confidence=low
GO	GO:0000123 (histone acetyltransferase complex); GO:0003713 (transcription coactivator activity); GO:0004402 (histone acetyltransferase activity); GO:0005667 (transcription regulator complex); GO:0008270 (zinc ion binding); GO:0016573 (GO:0016573); GO:0031490 (chromatin DNA binding); GO:0045944 (positive regulation of transcription by RNA polymerase II)
KEGG	smil03083 (Polycomb repressive complex - Salvia miltiorrhiza (redroot sage)); smil03250 (Viral life cycle - HIV-1 - Salvia miltiorrhiza (redroot sage)); smil04519 (Cadherin signaling - Salvia miltiorrhiza (redroot sage))
Pfam	PF00569 (ZZ); PF00628 (PHD); PF02135 (zf-TAZ); PF29847 (KAT3)
InterPro	-
eggNOG	-
NR	GeneID:131009428

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057792728.1`
2	Nucleoplasm	核质	1.00000	`XP_057792728.1`
3	Nuclear body	核内小体	0.20000	`XP_057792728.1`
4	Chromosome	染色体	0.00000	`XP_057792728.1`
5	Centromere	着丝粒	0.00000	`XP_057792728.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:74950876`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B102,B17,C44
`Chr2:74951684`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B27,B68,C1,D2
`Chr2:74952331`	`C`	`CG`	1bp_insertion	frameshift_variant	37	A11,A23,A24,A25,A4,A5,B1,B108,B118,B134,B140,B15,B42,B43,B54,B56,B59,B6,B73,B76,B85,B91,B96,B97,C16,C17,C23,C30,C34,C59,C67,C78,C83,C9,D10,D3,D9
`Chr2:74952759`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B27,B68,C1,C42,D2
`Chr2:74952781`	`A`	`AAC`	2bp_insertion	frameshift_variant	38	A11,A18,A24,A4,A5,B10,B110,B118,B120,B127,B134,B140,B15,B34,B42,B43,B5,B54,B56,B59,B63,B76,B85,B91,B96,C16,C17,C24,C30,C34,C50,C59,C67,C83,C85,C9,D1,D9
`Chr2:74952842`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A20,B105,B47,B67
`Chr2:74952844`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B118,B91,C24,C34,D1
`Chr2:74952847`	`A`	`AT`	1bp_insertion	frameshift_variant	3	B118,C34,D1
`Chr2:74952847`	`A`	`AT`	1bp_insertion	CDS_variant	3	B118,C34,D1
`Chr2:74953330`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A20,B105,B47,B67
`Chr2:74953706`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B27,B68,C1,C42,D2
`Chr2:74953719`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C70

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057792728.1

1729 aa

864

1729

zf-TAZ

PHD

KAT3

zf-TAZ

PF02135 zf-TAZ 672-741 aa PF00628 PHD 1058-1098 aa PF29847 KAT3 1159-1409 aa PF00569 ZZ 1555-1596 aa PF02135 zf-TAZ 1622-1692 aa

XP_057792729.1

1729 aa

864

1729

zf-TAZ

PHD

KAT3

zf-TAZ

PF02135 zf-TAZ 672-741 aa PF00628 PHD 1058-1098 aa PF29847 KAT3 1159-1409 aa PF00569 ZZ 1555-1596 aa PF02135 zf-TAZ 1622-1692 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057792728.1`	Pfam	`PF02135`	zf-TAZ	Family	672	741	5.5e-27	94.7	TAZ zinc finger
`XP_057792728.1`	Pfam	`PF00628`	PHD	Domain	1058	1098	7.9e-06	26.5	PHD-finger
`XP_057792728.1`	Pfam	`PF29847`	KAT3	Domain	1159	1409	9.4e-80	269.1	Histone acetyltransferase domain KAT3
`XP_057792728.1`	Pfam	`PF00569`	ZZ	Domain	1555	1596	1.1e-05	25.8	Zinc finger, ZZ type
`XP_057792728.1`	Pfam	`PF02135`	zf-TAZ	Family	1622	1692	5.5e-27	94.7	TAZ zinc finger
`XP_057792729.1`	Pfam	`PF02135`	zf-TAZ	Family	672	741	5.5e-27	94.7	TAZ zinc finger
`XP_057792729.1`	Pfam	`PF00628`	PHD	Domain	1058	1098	7.9e-06	26.5	PHD-finger
`XP_057792729.1`	Pfam	`PF29847`	KAT3	Domain	1159	1409	9.4e-80	269.1	Histone acetyltransferase domain KAT3
`XP_057792729.1`	Pfam	`PF00569`	ZZ	Domain	1555	1596	1.1e-05	25.8	Zinc finger, ZZ type
`XP_057792729.1`	Pfam	`PF02135`	zf-TAZ	Family	1622	1692	5.5e-27	94.7	TAZ zinc finger

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057936745.1
GTCAGAAAAAAAGAAAATTAACAAAAATACCCAAATTCTAAATCAGCCCAATTTTTTCTCCAAACTACCGTTCTCCGCCGTAATCTTGGCGCGACCGCCGGTTAAGCTCCAGCACCGCCGTGGCTGGCTCGTTTGGCATTCTATAACTTATTTGCGTATTTATCTGTTCGTTTCAGCTCCCGTTTTCGTGTCTGGTTTGGACTTTTGCGGTTTCATTGCTTTGAACTTGATTAGATCAACTTTGTTTGACGCCTTTGTTA...

XM_057936746.1
GAAAATTAACAAAAATACCCAAATTCTAAATCAGCCCAATTTTTTCTCCAAACTACCGTTCTCCGCCGTAATCTTGGCGCGACCGCCGGTTAAGCTCCAGCACCGCCGTGGCTGGCTCGTTTGGCATTCTATAACTTATTTGCGTATTTATCTGTTTTCGTGTCTGGTTTGGACTTTTGCGGTTTCATTGCTTTGAACTTGATTAGATCAACTTTGTTTGACGCCTTTGTTATGGTCTTTGGCTCTAGTTGGTGGTCTAA...

CDS

2 records

下载 CDS FASTA

LOC131009428
ATGAATCTACAGACACATCATACGGGGCAAATCTCAGGCCAGGTACCCAACCAAGCTGGTACTATGTTGCCTGGGCTACCACAGCAGAATGGGAACCCTATGGCCAGCCAAATGCAGAATCCTAATGTTCATCGAAATGTAGCCAATATGGACCCAGAAACTACTAAAAGACGCAAATACATGCAAGAGAAAATCTGGAACTTTCTTATGCAGCGGCGCCAACAATCTCCTGAGGTTCCCAACAGGAAAATGGTTGATAT...

Protein

2 records

下载 Protein FASTA

XP_057792728.1
MNLQTHHTGQISGQVPNQAGTMLPGLPQQNGNPMASQMQNPNVHRNVANMDPETTKRRKYMQEKIWNFLMQRRQQSPEVPNRKMVDIVKRLEDGLFRSATTMEEYLNLETLERRLHILIKRFPTTTSNHNQQMSHSNASPPIGTMIPTPGFQQTGNSSFGGTSSVDNSFVNNVNNSSSNTIASSTINSGSFFPTRNGSSGSAHGALAGGYQQSPNAFMVNPGGNNMMTSMGAQRMTSQMIPTPGISNSNTNDMISNTSNN...

XP_057792729.1
MNLQTHHTGQISGQVPNQAGTMLPGLPQQNGNPMASQMQNPNVHRNVANMDPETTKRRKYMQEKIWNFLMQRRQQSPEVPNRKMVDIVKRLEDGLFRSATTMEEYLNLETLERRLHILIKRFPTTTSNHNQQMSHSNASPPIGTMIPTPGFQQTGNSSFGGTSSVDNSFVNNVNNSSSNTIASSTINSGSFFPTRNGSSGSAHGALAGGYQQSPNAFMVNPGGNNMMTSMGAQRMTSQMIPTPGISNSNTNDMISNTSNN...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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