Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr02G005531`

染色体: Chr02 坐标: 75364076-75367481 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr02G005531`
名称	SmilChr02G005531
描述	endonuclease III homolog 1, chloroplastic-like
染色体 / SeqID	Chr02 / NC_080388.1
坐标与链方向	75364076 - 75367481 / `-`

ID 对照

NCBI Gene ID	`LOC131009492`
GeneID	`131009492`
locus_tag	`-`
NCBI Name	`LOC131009492`
原始查询	`SmilChr02G005531`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	endonuclease III homolog 1, chloroplastic-like
产物	endonuclease III homolog 1%2C chloroplastic-like
Arabidopsis	`AT2G31450` (ATNTH1) DNA glycosylase superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:817703] identity=62.4; qcov=0.9; evalue=5.81e-142; confidence=high
Rice	`Os12g0212100` - identity=25.2; qcov=0.625; evalue=1.79e-07; confidence=low
GO	GO:0000703 (oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity); GO:0003677 (DNA binding); GO:0003906 (DNA-(apurinic or apyrimidinic site) endonuclease activity); GO:0005634 (nucleus); GO:0006284 (base-excision repair); GO:0006285 (base-excision repair, AP site formation); GO:0006289 (nucleotide-excision repair); GO:0042644 (chloroplast nucleoid); GO:0051539 (4 iron, 4 sulfur cluster binding)
KEGG	smil03410 (Base excision repair - Salvia miltiorrhiza (redroot sage))
Pfam	PF00633 (HHH); PF00730 (HhH-GPD)
InterPro	-
eggNOG	-
NR	GeneID:131009492

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057792836.1`
2	Mitochondrion	线粒体	0.60000	`XP_057792836.1`
3	Chromosome	染色体	0.00000	`XP_057792836.1`
4	Centromere	着丝粒	0.00000	`XP_057792836.1`
5	Chromatin	染色质	0.00000	`XP_057792836.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr2:75364349`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B57,C60
`Chr2:75364354`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B50
`Chr2:75364370`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B23
`Chr2:75364377`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B122,B36,C44
`Chr2:75364414`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C20
`Chr2:75364435`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B50,B73,C14
`Chr2:75364441`	`GC`	`G`	1bp_deletion	frameshift_variant	1	B136
`Chr2:75364441`	`GC`	`G`	1bp_deletion	CDS_variant	1	B136
`Chr2:75364891`	`T`	`TC`	1bp_insertion	frameshift_variant	1	A22
`Chr2:75364891`	`T`	`TC`	1bp_insertion	CDS_variant	1	A22
`Chr2:75364897`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B93
`Chr2:75364953`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B29,B50,C14,C28,C42

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057792836.1

350 aa

175

350

HhH-GPD

HHH

PF00730 HhH-GPD 154-293 aa PF00633 HHH 221-249 aa

XP_057792837.1

349 aa

174

349

HhH-GPD

HHH

PF00730 HhH-GPD 154-292 aa PF00633 HHH 220-248 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057792836.1`	Pfam	`PF00730`	HhH-GPD	Domain	154	293	6.6e-21	75.4	HhH-GPD superfamily base excision DNA repair protein
`XP_057792836.1`	Pfam	`PF00633`	HHH	Motif	221	249	3.9e-09	36.6	Helix-hairpin-helix motif
`XP_057792837.1`	Pfam	`PF00730`	HhH-GPD	Domain	154	292	1e-22	81.2	HhH-GPD superfamily base excision DNA repair protein
`XP_057792837.1`	Pfam	`PF00633`	HHH	Motif	220	248	3.8e-09	36.6	Helix-hairpin-helix motif

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057936853.1
AAATATAATCTTAAATTCAAGCCAACCTAACATCATTAAATACCAAAGCGACATTTTTCTTTAGTTTTTTTCCCCTAAAATTTCTATATCAAACTCCCATATAATTCATTCATAATAAAAACTTAAAATAAAGATAAATAAATCCACATATTTCAAAGCCTTAAATTAATTTTTCCTCTTCCACCAAAAATAATGTCCCTTCCACTCAAGAACTTTTCTGCAATTGTACATTTAATTTCCCCAAAATCATTTCCCTCATT...

XM_057936854.1
ATCTTAAATTCAAGCCAACCTAACATCATTAAATACCAAAGCGACATTTTTCTTTAGTTTTTTTCCCCTAAAATTTCTATATCAAACTCCCATATAATTCATTCATAATAAAAACTTAAAATAAAGATAAATAAATCCACATATTTCAAAGCCTTAAATTAATTTTTCCTCTTCCACCAAAAATAATGTCCCTTCCACTCAAGAACTTTTCTGCAATTGTACATTTAATTTCCCCAAAATCATTTCCCTCATTCCGCAAA...

CDS

2 records

下载 CDS FASTA

LOC131009492
ATGTCCCTTCCACTCAAGAACTTTTCTGCAATTGTACATTTAATTTCCCCAAAATCATTTCCCTCATTCCGCAAAATGCACACAACTAGATTATCGGCAGCGAAAAGGGAGATAGACCCATCAGCTGAATCGAAAAACCCAGATGATGATTCTGTAACGAAACTTCGTGTCTTTGTAAGGAAAAAGAGAGCTAAAAAAACCGTTCAAGCTATAGTTGAAGCGATTAAGCCTGAAACTTTTGATCAAAAGCCTTGCAGCCT...

Protein

2 records

下载 Protein FASTA

XP_057792836.1
MSLPLKNFSAIVHLISPKSFPSFRKMHTTRLSAAKREIDPSAESKNPDDDSVTKLRVFVRKKRAKKTVQAIVEAIKPETFDQKPCSLPEIEDFAYGKQSSFSRSNEVQPPSDWEKVIEGIRKMRSSEDAPVDSMGCEKAGVSLPPKERRFAVLISSLLSSQTKDQVTHGAIQRLLQNDLLSAEALDKADEGAIKELIHPQVGFYSRKASNMRKVAKICLDRYNGDIPSTLEELLELPGIGPKMAHLVMNVGWNNVQGICV...

XP_057792837.1
MSLPLKNFSAIVHLISPKSFPSFRKMHTTRLSAAKREIDPSAESKNPDDDSVTKLRVFVRKKRAKKTVQAIVEAIKPETFDQKPCSLPEIEDFAYGKQSSFSRSNEVQPPSDWEKVIEGIRKMRSSEDAPVDSMGCEKAGVSLPPKERRFAVLISSLLSSQTKDQVTHGAIQRLLQNDLLSAEALDKADEGAIKELIHPVGFYSRKASNMRKVAKICLDRYNGDIPSTLEELLELPGIGPKMAHLVMNVGWNNVQGICVD...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

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