Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr03G000809`

染色体: Chr03 坐标: 9251891-9255960 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr03G000809`
名称	SmilChr03G000809
描述	SEC12-like protein 2
染色体 / SeqID	Chr03 / NC_080389.1
坐标与链方向	9251891 - 9255960 / `+`

ID 对照

NCBI Gene ID	`LOC131017416`
GeneID	`131017416`
locus_tag	`-`
NCBI Name	`LOC131017416`
原始查询	`SmilChr03G000809`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	SEC12-like protein 2
产物	SEC12-like protein 2
Arabidopsis	`AT5G50650` (AT5G50550) Transducin/WD40 repeat-like superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:835135] identity=47.1; qcov=0.938; evalue=7.6e-98; confidence=high
Rice	`Os11g0610700` (OsWD40-190) - identity=44; qcov=1.03; evalue=5.44e-99; confidence=medium
GO	GO:0003400 (GO:0003400); GO:0005085 (guanyl-nucleotide exchange factor activity); GO:0005096 (GTPase activator activity); GO:0005515 (protein binding); GO:0005789 (endoplasmic reticulum membrane); GO:0009306 (protein secretion)
KEGG	smil04141 (Protein processing in endoplasmic reticulum - Salvia miltiorrhiza (redroot sage))
Pfam	PF00400 (WD40); PF12894 (ANAPC4_WD40)
InterPro	-
eggNOG	-
NR	GeneID:131017416

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Endoplasmic reticulum	内质网	0.60000	`XP_057802152.1`
2	Cytosol	细胞质基质	0.40000	`XP_057802152.1`
3	Endoplasmic reticulum membrane	内质网膜	0.20000	`XP_057802152.1`
4	Nucleus	细胞核	0.00000	`XP_057802152.1`
5	Chromosome	染色体	0.00000	`XP_057802152.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr3:9251974`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A9,B100,B113,C36,D5
`Chr3:9251993`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B100,C36,C69
`Chr3:9252139`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B81,B9,C54,C86
`Chr3:9252172`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C85
`Chr3:9253755`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B126,B94,C35,D6
`Chr3:9253767`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B115
`Chr3:9254556`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B126,B45,B47
`Chr3:9254651`	`TGG`	`T`	2bp_deletion	frameshift_variant	27	A20,B106,B118,B121,B136,B25,B36,B38,B4,B46,B56,B57,B67,B69,B7,B73,B96,B97,C20,C21,C36,C44,C63,C66,C80,C87,D10
`Chr3:9254655`	`A`	`ACC`	2bp_insertion	frameshift_variant	26	A20,B106,B118,B121,B136,B25,B36,B38,B4,B56,B57,B67,B69,B7,B73,B96,B97,C20,C21,C36,C44,C63,C66,C80,C87,D10
`Chr3:9254688`	`AG`	`A`	1bp_deletion	frameshift_variant	9	B126,B47,B74,C35,C36,C38,C70,C71,D6
`Chr3:9255244`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B81
`Chr3:9255254`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B15,C51

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057802152.1

374 aa

187

374

WD40

ANAPC4_WD40

WD40

PF00400 WD40 141-163 aa PF00400 WD40 174-197 aa PF12894 ANAPC4_WD40 257-320 aa PF00400 WD40 308-335 aa

XP_057802153.1

373 aa

186

373

WD40

ANAPC4_WD40

WD40

PF00400 WD40 141-163 aa PF00400 WD40 174-197 aa PF12894 ANAPC4_WD40 257-320 aa PF00400 WD40 308-335 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057802152.1`	Pfam	`PF00400`	WD40	Repeat	141	163	1e-17	64.5	WD domain, G-beta repeat
`XP_057802152.1`	Pfam	`PF00400`	WD40	Repeat	174	197	1e-17	64.5	WD domain, G-beta repeat
`XP_057802152.1`	Pfam	`PF12894`	ANAPC4_WD40	Repeat	257	320	3e-13	50.5	Anaphase-promoting complex subunit 4 WD40 domain
`XP_057802152.1`	Pfam	`PF00400`	WD40	Repeat	308	335	1e-17	64.5	WD domain, G-beta repeat
`XP_057802153.1`	Pfam	`PF00400`	WD40	Repeat	141	163	9.9e-18	64.5	WD domain, G-beta repeat
`XP_057802153.1`	Pfam	`PF00400`	WD40	Repeat	174	197	9.9e-18	64.5	WD domain, G-beta repeat
`XP_057802153.1`	Pfam	`PF12894`	ANAPC4_WD40	Repeat	257	320	2.8e-13	50.6	Anaphase-promoting complex subunit 4 WD40 domain
`XP_057802153.1`	Pfam	`PF00400`	WD40	Repeat	308	335	9.9e-18	64.5	WD domain, G-beta repeat

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057946170.1
CGATCCTCAGAGTAACACACGTTCCTGTATATTTTCCACTACCACGTTGTATCACATTCACAGCGGAGCAAGAAAGCATGGGGGAGGCGGGCAAAGAATTTAGCTGCAAGAATTATGGAGTCCCACTGTACGCCGCCGCCTGGGTTCCATCTGCCGCCGTTAGATTACATACCGCCAACGAGTTGAAAATTCCTGCCAAACCCCTCGTTGTCCTAGCCGGAGGCGGCGGAGAAGGCAACACCGGAATACCAAATGCCCTC...

XM_057946169.1
GATCCTCAGAGTAACACACGTTCCTGTATATTTTCCACTACCACGTTGTATCACATTCACAGCGGAGCAAGAAAGCATGGGGGAGGCGGGCAAAGAATTTAGCTGCAAGAATTATGGAGTCCCACTGTACGCCGCCGCCTGGGTTCCATCTGCCGCCGTTAGATTACATACCGCCAACGAGTTGAAAATTCCTGCCAAACCCCTCGTTGTCCTAGCCGGAGGCGGCGGAGAAGGCAACACCGGAATACCAAATGCCCTCC...

CDS

2 records

下载 CDS FASTA

LOC131017416
ATGGGGGAGGCGGGCAAAGAATTTAGCTGCAAGAATTATGGAGTCCCACTGTACGCCGCCGCCTGGGTTCCATCTGCCGCCGTTAGATTACATACCGCCAACGAGTTGAAAATTCCTGCCAAACCCCTCGTTGTCCTAGCCGGAGGCGGCGGAGAAGGCAACACCGGAATACCAAATGCCCTCCTCCTCTCGGCCTTTGATTCCGAATCCTGCGCCCTCTCTGATCAGCCTGTGGCTAAGCTTGGAACTGGTAGCGATCT...

Protein

2 records

下载 Protein FASTA

XP_057802152.1
MGEAGKEFSCKNYGVPLYAAAWVPSAAVRLHTANELKIPAKPLVVLAGGGGEGNTGIPNALLLSAFDSESCALSDQPVAKLGTGSDLPYRIGVHPGGEGIICSFLTKKCRWFEWDSNGQTLRLKSSEKVLKPLEDVGLQLALTFNTEGNLLAVGGEDGKLRVFKWPAMESILSETNAHPSVEDLDFSPDGKFLVSVGSGPGRIWDVASSSSVASLPQENDEIFRFCRFSRSIGTDQVLYITTKRDKGGSIVKWNPTSWER...

XP_057802153.1
MGEAGKEFSCKNYGVPLYAAAWVPSAAVRLHTANELKIPAKPLVVLAGGGGEGNTGIPNALLLSAFDSESCALSDQPVAKLGTGSDLPYRIGVHPGGEGIICSFLTKKCRWFEWDSNGQTLRLKSSEKVLKPLEDVGLQLALTFNTEGNLLAVGGEDGKLRVFKWPAMESILSETNAHPSVEDLDFSPDGKFLVSVGSGPGRIWDVASSSSVASLPQENDEIFRFCRFSRSIGTDQVLYITTKRDKGGSIVKWNPTSWER...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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