Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr03G002342`

染色体: Chr03 坐标: 36920193-36924630 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr03G002342`
名称	SmilChr03G002342
描述	calcium-dependent protein kinase 13
染色体 / SeqID	Chr03 / NC_080389.1
坐标与链方向	36920193 - 36924630 / `-`

ID 对照

NCBI Gene ID	`LOC131016542`
GeneID	`131016542`
locus_tag	`-`
NCBI Name	`LOC131016542`
原始查询	`SmilChr03G002342`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	calcium-dependent protein kinase 13
产物	calcium-dependent protein kinase 13
Arabidopsis	`AT3G51850` (CPK13) calcium-dependent protein kinase 13 [Source:NCBI gene (formerly Entrezgene);Acc:824348] identity=85.2; qcov=0.998; evalue=0; confidence=high
Rice	`Os05g0467000` (OsCDPK16) - identity=78; qcov=1.03; evalue=0; confidence=high
GO	GO:0004683 (calcium/calmodulin-dependent protein kinase activity); GO:0005509 (calcium ion binding); GO:0005516 (calmodulin binding); GO:0005524 (ATP binding); GO:0005634 (nucleus); GO:0005737 (cytoplasm); GO:0009931 (calcium-dependent protein serine/threonine kinase activity); GO:0018105 (peptidyl-serine phosphorylation); GO:0035556 (intracellular signal transduction); GO:0046777 (protein autophosphorylation)
KEGG	smil04075 (Plant hormone signal transduction - Salvia miltiorrhiza (redroot sage)); smil04626 (Plant-pathogen interaction - Salvia miltiorrhiza (redroot sage))
Pfam	PF00036 (EF-hand_1); PF00069 (Pkinase); PF06293 (Kdo); PF07714 (PK_Tyr_Ser-Thr); PF13202 (EF-hand_5); PF13405 (EF-hand_6); PF13499 (EF-hand_7); PF13833 (EF-hand_8)
InterPro	-
eggNOG	-
NR	GeneID:131016542

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057801240.1`
2	Cytosol	细胞质基质	0.80000	`XP_057801240.1`
3	Cytoplasm	细胞质	0.20000	`XP_057801240.1`
4	Nucleus	细胞核	0.00000	`XP_057801240.1`
5	Chromosome	染色体	0.00000	`XP_057801240.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr3:36920909`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D6
`Chr3:36921273`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B9,D6
`Chr3:36921275`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B9,D6
`Chr3:36921299`	`T`	`TA`	1bp_insertion	frameshift_variant	48	A14,A16,A20,A5,A7,A9,B103,B106,B108,B112,B119,B122,B128,B129,B133,B134,B135,B138,B15,B21,B25,B26,B34,B36,B42,B45,B56,B71,B90,C12,C19,C26,C27,C31,C39,C5,C52,C59,C6,C60,C61,C67,C69,C76,D3,D5,D6,D8
`Chr3:36921306`	`T`	`TTC`	2bp_insertion	frameshift_variant	48	A14,A16,A20,A5,A7,A9,B103,B106,B108,B112,B119,B122,B128,B129,B133,B134,B135,B138,B15,B21,B25,B26,B34,B36,B42,B45,B56,B71,B90,C12,C19,C26,C27,C31,C39,C5,C52,C59,C6,C60,C61,C67,C69,C76,D3,D5,D6,D8
`Chr3:36922224`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B107,C57
`Chr3:36923702`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B56
`Chr3:36923916`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr3:36923979`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B140,C27,C36
`Chr3:36924185`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B127
`Chr3:36924197`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B106,C22
`Chr3:36924236`	`ACT`	`A`	2bp_deletion	frameshift_variant	54	A11,A13,A2,A25,A5,A9,B100,B102,B108,B114,B123,B130,B131,B137,B139,B140,B16,B18,B2,B20,B38,B46,B47,B48,B53,B68,B81,B89,B9,B94,B96,B99,C12,C15,C21,C22,C27,C28,C40,C41,C44,C49,C52,C55,C56,C57,C60,C7,C70,C75,C78,C80,D5,D9

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057801240.1

528 aa

264

528

Pkinase

PK_Tyr_Ser-Thr

Kdo

EF-hand_7

EF-hand_5

EF-hand_1

EF-hand_6

EF-hand_8

EF-hand_7

EF-hand_1

EF-hand_6

EF-hand_5

EF-hand_8

EF-hand_1

EF-hand_5

EF-hand_6

PF00069 Pkinase 57-313 aa PF07714 PK_Tyr_Ser-Thr 58-309 aa PF06293 Kdo 84-201 aa PF13499 EF-hand_7 360-420 aa PF13202 EF-hand_5 361-383 aa PF00036 EF-hand_1 361-386 aa PF13405 EF-hand_6 361-386 aa PF13833 EF-hand_8 390-418 aa PF13833 EF-hand_8 409-457 aa PF13499 EF-hand_7 431-494 aa PF00036 EF-hand_1 433-458 aa PF13405 EF-hand_6 433-459 aa PF13202 EF-hand_5 435-457 aa PF13833 EF-hand_8 469-494 aa PF00036 EF-hand_1 470-495 aa PF13202 EF-hand_5 471-493 aa PF13405 EF-hand_6 471-494 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057801240.1`	Pfam	`PF00069`	Pkinase	Domain	57	313	4.5e-76	256.4	Protein kinase domain
`XP_057801240.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	58	309	9.1e-25	88.1	Protein tyrosine and serine/threonine kinase
`XP_057801240.1`	Pfam	`PF06293`	Kdo	Family	84	201	6.8e-05	23.1	Lipopolysaccharide kinase (Kdo/WaaP) family
`XP_057801240.1`	Pfam	`PF13499`	EF-hand_7	Domain	360	420	1.7e-29	102.7	EF-hand domain pair
`XP_057801240.1`	Pfam	`PF13202`	EF-hand_5	Domain	361	383	9.1e-21	73.0	EF hand
`XP_057801240.1`	Pfam	`PF00036`	EF-hand_1	Domain	361	386	1e-29	100.5	EF hand domain
`XP_057801240.1`	Pfam	`PF13405`	EF-hand_6	Domain	361	386	1.2e-25	87.4	EF-hand domain
`XP_057801240.1`	Pfam	`PF13833`	EF-hand_8	Domain	390	418	1.3e-16	60.8	EF-hand domain pair
`XP_057801240.1`	Pfam	`PF13833`	EF-hand_8	Domain	409	457	1.3e-16	60.8	EF-hand domain pair
`XP_057801240.1`	Pfam	`PF13499`	EF-hand_7	Domain	431	494	1.7e-29	102.7	EF-hand domain pair
`XP_057801240.1`	Pfam	`PF00036`	EF-hand_1	Domain	433	458	1e-29	100.5	EF hand domain
`XP_057801240.1`	Pfam	`PF13405`	EF-hand_6	Domain	433	459	1.2e-25	87.4	EF-hand domain
`XP_057801240.1`	Pfam	`PF13202`	EF-hand_5	Domain	435	457	9.1e-21	73.0	EF hand
`XP_057801240.1`	Pfam	`PF13833`	EF-hand_8	Domain	469	494	1.3e-16	60.8	EF-hand domain pair
`XP_057801240.1`	Pfam	`PF00036`	EF-hand_1	Domain	470	495	1e-29	100.5	EF hand domain
`XP_057801240.1`	Pfam	`PF13202`	EF-hand_5	Domain	471	493	9.1e-21	73.0	EF hand
`XP_057801240.1`	Pfam	`PF13405`	EF-hand_6	Domain	471	494	1.2e-25	87.4	EF-hand domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057945257.1
TCTCACTCCTTGTGTATATAATAAAAAATAAAGATTTCTCACTCTACAAAAGTATTAGAAGAGCCGTTTCCGTACACACCACTAATTGAAGACTGGAAAACCCCCTTTCCCTTTTCACACAGAAACACACAAATTCTGCCATTTGTGCGTGAAAAATCACACGCATTGTCTCCCCTAAGCTCCACTTCACTCCGAATGAGGCTAGGGTTTCACTCTCCAGCTATGTGAGAGCCTAGCTACTGCGCTTGGAGTTAGGGTTT...

CDS

1 records

下载 CDS FASTA

LOC131016542
ATGGGGAACTGCTGCAGATCTCCGGCAGCCGTCGCTAGAGAAGACGTCAAATCTTCCAACTTCTCCGGCCATGATCACGGCCGGAAGGAGAAGTCGTCGGGCAACGTGAAGAAAGCAATCACAGTTCTGACAGATGTGAAGAAGGAGAACATTGATGAGAAGTATTTAATCGACAGAGAGCTCGGCCGCGGCGAATTCGGGGTCACTTATCTATGCATTGACCGGGAGACGAAGGAGCTGCTGGCCTGCAAGTCAATATC...

Protein

1 records

下载 Protein FASTA

XP_057801240.1
MGNCCRSPAAVAREDVKSSNFSGHDHGRKEKSSGNVKKAITVLTDVKKENIDEKYLIDRELGRGEFGVTYLCIDRETKELLACKSISKRKLRTAVDVEDVRREVAIMKHLPRNSSIVSFKEACEDENAVHLVMELCEGGELFDRIVARGHYTERAAAAVMRTIVEVVQLCHKHGVIHRDLKPENFLFANKKENSPLKAIDFGLSIFFKPGERFSEIVGSPYYMAPEVLKRSYGPEIDIWSAGVILYILLCGVPPFWAESE...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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