Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr03G002560`

染色体: Chr03 坐标: 40776711-40781619 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr03G002560`
名称	SmilChr03G002560
描述	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, chloroplastic-like
染色体 / SeqID	Chr03 / NC_080389.1
坐标与链方向	40776711 - 40781619 / `-`

ID 对照

NCBI Gene ID	`LOC131016718`
GeneID	`131016718`
locus_tag	`-`
NCBI Name	`LOC131016718`
原始查询	`SmilChr03G002560`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, chloroplastic-like
产物	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase%2C chloroplastic-like
Arabidopsis	`AT2G36230` (APG10) Aldolase-type TIM barrel family protein [Source:NCBI gene (formerly Entrezgene);Acc:818195] identity=74.6; qcov=0.877; evalue=1.59e-152; confidence=high
Rice	`Os05g0400800` - identity=75; qcov=0.49; evalue=9.98e-82; confidence=medium
GO	GO:0000105 (L-histidine biosynthetic process); GO:0000162 (L-tryptophan biosynthetic process); GO:0003949 (1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity); GO:0005737 (cytoplasm)
KEGG	smil00340 (Histidine metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF00977 (His_biosynth)
InterPro	-
eggNOG	-
NR	GeneID:131016718

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057801402.1`
2	Chloroplast stroma	叶绿体基质	0.80000	`XP_057801402.1`
3	Nucleus	细胞核	0.00000	`XP_057801402.1`
4	Chromosome	染色体	0.00000	`XP_057801402.1`
5	Centromere	着丝粒	0.00000	`XP_057801402.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr3:40776950`	`C`	`T`	EMS_canonical_SNV	stop_gained	9	A10,B23,B29,B42,B43,B49,B90,C26,C42
`Chr3:40776964`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A14,B50
`Chr3:40777024`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	A4
`Chr3:40777033`	`CCG`	`C`	2bp_deletion	frameshift_variant	3	B114,B73,C71
`Chr3:40777033`	`CCG`	`C`	2bp_deletion	CDS_variant	3	B114,B73,C71
`Chr3:40777367`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D7
`Chr3:40777390`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B123,B46,C37
`Chr3:40777632`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C37
`Chr3:40777677`	`G`	`A`	EMS_canonical_SNV	stop_gained	21	A11,A14,B125,B127,B24,B32,B33,B48,B58,B69,B80,B9,B94,C14,C3,C31,C37,C42,C66,C73,C78
`Chr3:40778064`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A11,B67,B75,C4,D10
`Chr3:40778065`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A11,B67,B75,C4,D10
`Chr3:40778073`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B74,B97,D11

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057801402.1

310 aa

155

310

His_biosynth

PF00977 His_biosynth 53-286 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057801402.1`	Pfam	`PF00977`	His_biosynth	Family	53	286	1.7e-27	97.1	Histidine biosynthesis protein

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057945419.1
ATTTAAACCAAAACAAGATATTTCCTTATGATTTTCTTTTAAACCATTTTAAGCGCGGATCAAAGATTAAAAGAAAACATCAAAAGGAAATATCTTGTTTTGGTTTAAATGTTTCAAATAATAACATAAATGGGTCTTTGTATAATTATTTACAAAAAAAGGGTTGTTTTTTGAATTTTTAAGAATTAAGTCGTGTCAAATTTGGACAACAACGAAAGTTGGTGTATTAAAATATAAAATCCTAACTTCGCGTCAAATAT...

CDS

1 records

下载 CDS FASTA

LOC131016718
ATGAGCATTCACCGTCTTCAAGCAACTTCATGGAAAGATTTTACTGAGCTTTCTGTGTTGTATGCACCTCGAGGCAAGAAAATTTTGGTCCATGCTGCACCTTGGGTGATCCAGAGAAGTCGAAGGTTATCTATACAATGTGCCGTCAAGTTTCGTCCTTGCATTGACATACATAAGGGGAAAGTGAAACAGATTGTTGGATCCACTCTTCGAGATTCTAAAGAGGGAGATTCAAGTCTTATCACTAATTACGAATCTGA...

Protein

1 records

下载 Protein FASTA

XP_057801402.1
MSIHRLQATSWKDFTELSVLYAPRGKKILVHAAPWVIQRSRRLSIQCAVKFRPCIDIHKGKVKQIVGSTLRDSKEGDSSLITNYESDLSAAEYAKMYMDDGLTGGHMIMLGTDPLSKAAAVEALHAYPGGLQVGGGINTRNALTYIGEGASHVIVTSYVFSDGQVDFERLKEFAQVVGKERLVLDLSCRKKDGRYAVVTDRWQKFTDVFLDQEVLNFLAGHADEFLVHGVDVEGKKLGIDEELVELLGRISPIPVTYAGG...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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