Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr03G002787`

染色体: Chr03 坐标: 44374577-44378103 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr03G002787`
名称	SmilChr03G002787
描述	S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferase, chloroplastic
染色体 / SeqID	Chr03 / NC_080389.1
坐标与链方向	44374577 - 44378103 / `-`

ID 对照

NCBI Gene ID	`LOC131015956`
GeneID	`131015956`
locus_tag	`-`
NCBI Name	`LOC131015956`
原始查询	`SmilChr03G002787`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferase, chloroplastic
产物	S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferase%2C chloroplastic
Arabidopsis	`AT5G40850` (UPM1) urophorphyrin methylase 1 [Source:NCBI gene (formerly Entrezgene);Acc:834085] identity=72.7; qcov=1.02; evalue=0; confidence=high
Rice	`Os01g0631200` - identity=85; qcov=0.529; evalue=7.34e-118; confidence=medium
GO	GO:0004851 (uroporphyrin-III C-methyltransferase activity); GO:0019354 (siroheme biosynthetic process)
KEGG	smil00860 (Porphyrin metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01240 (Biosynthesis of cofactors - Salvia miltiorrhiza (redroot sage))
Pfam	PF00590 (TP_methylase)
InterPro	-
eggNOG	-
NR	GeneID:131015956

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057800457.1`
2	Chloroplast stroma	叶绿体基质	1.00000	`XP_057800457.1`
3	Nucleus	细胞核	0.00000	`XP_057800457.1`
4	Chromosome	染色体	0.00000	`XP_057800457.1`
5	Centromere	着丝粒	0.00000	`XP_057800457.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr3:44374827`	`AT`	`A`	1bp_deletion	frameshift_variant	20	A19,B103,B127,B128,B16,B26,B51,B73,B79,B91,C15,C16,C27,C31,C39,C4,C45,C49,C54,C57
`Chr3:44374918`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B93,C39
`Chr3:44374921`	`TAC`	`T`	2bp_deletion	frameshift_variant	2	B93,C39
`Chr3:44374921`	`TAC`	`T`	2bp_deletion	CDS_variant	2	B93,C39
`Chr3:44374936`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B93,C39
`Chr3:44374939`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B93,C39
`Chr3:44374942`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B93,C39
`Chr3:44374949`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A2,B93,C39
`Chr3:44375172`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B114,B122,B19
`Chr3:44375194`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B33
`Chr3:44375260`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B46
`Chr3:44375310`	`G`	`A`	EMS_canonical_SNV	stop_gained	14	A13,A15,B128,B48,B88,C14,C2,C62,C64,C66,C81,C82,C86,D4

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057800457.1

368 aa

184

368

TP_methylase

PF00590 TP_methylase 115-328 aa

XP_057800458.1

367 aa

184

367

TP_methylase

PF00590 TP_methylase 115-327 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057800457.1`	Pfam	`PF00590`	TP_methylase	Domain	115	328	2e-51	175.7	Tetrapyrrole (Corrin/Porphyrin) Methylases
`XP_057800458.1`	Pfam	`PF00590`	TP_methylase	Domain	115	327	7.5e-52	177.1	Tetrapyrrole (Corrin/Porphyrin) Methylases

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057944475.1
GTCCATAAATTTCATGAATAAACAAAATTTTAATTTTTGAGGGTCTCCTAAAATTGTCTATGTCCAGTTTTGAAAAGCTAAGCATAGTTGCCTTCTCATCGCCTCCAAAAGCTTCAAAAAGCGTCTCCCCGACAATCCAACTCAGAATTGCCCTCTTCCCCTCATCACGTCCCCCTACACAAATGTATATAAACCCACATTCTTTCTCTCCAAAACCAATCTTTCTTTCTCTACAAACCTACACATTCAATTAAAATCCA...

XM_057944474.1
TCTCCTAAAATTGTCTATGTCCAGTTTTGAAAAGCTAAGCATAGTTGCCTTCTCATCGCCTCCAAAAGCTTCAAAAAGCGTCTCCCCGACAATCCAACTCAGAATTGCCCTCTTCCCCTCATCACGTCCCCCTACACAAATGTATATAAACCCACATTCTTTCTCTCCAAAACCAATCTTTCTTTCTCTACAAACCTACACATTCAATTAAAATCCAAACTTGGTTGCCATTCCAAATACCCCAATGGCCCTATTAGGCA...

CDS

2 records

下载 CDS FASTA

LOC131015956
ATGGCCCTATTAGGCAGACTCTCATCTTCAACACCACCATTTCAATCAGCTAATCCCAACTCATCTGTCCAAAAACAGGTTTTCACCATCAATTGCTCGTCCAATTCGCAAAAGGCGTCACCTTTCACTGAAAAGCATTCAATCGAGAGGTACCAGCGGGACAGCTGGGTGTACAAGAGCAAGTTGCCGCAGCCCTCGTGTTCCTGCCAGCTCCCGTCTGATCAAGAGTTCGTTAGGGATTATGACATAGCTATGCAGCT...

Protein

2 records

下载 Protein FASTA

XP_057800457.1
MALLGRLSSSTPPFQSANPNSSVQKQVFTINCSSNSQKASPFTEKHSIERYQRDSWVYKSKLPQPSCSCQLPSDQEFVRDYDIAMQLPELKKLLEVLREKRRNENGCERKGPGNVFLVGTGPGDPELLTIKALRVIESADLLLYDRLVSNDVLNLVGPNANLLYVGKTAGYHSRTQQEEIHELLLSFAEAGATVVRLKGGDPLVFGRGGEEMDFLQQQGIEVKVIPGITAASGIAAELGIPLTHRGVANSVRFLTGHSRK...

XP_057800458.1
MALLGRLSSSTPPFQSANPNSSVQKQVFTINCSSNSQKASPFTEKHSIERYQRDSWVYKSKLPQPSCSCQLPSDQEFVRDYDIAMQLPELKKLLEVLREKRRNENGCERKGPGNVFLVGTGPGDPELLTIKALRVIESADLLLYDRLVSNDVLNLVGPNANLLYVGKTAGYHSRTQEEIHELLLSFAEAGATVVRLKGGDPLVFGRGGEEMDFLQQQGIEVKVIPGITAASGIAAELGIPLTHRGVANSVRFLTGHSRKG...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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