Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr03G002949`

染色体: Chr03 坐标: 46212992-46223199 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr03G002949`
名称	SmilChr03G002949
描述	protein EXPORTIN 1A
染色体 / SeqID	Chr03 / NC_080389.1
坐标与链方向	46212992 - 46223199 / `+`

ID 对照

NCBI Gene ID	`LOC131016067`
GeneID	`131016067`
locus_tag	`-`
NCBI Name	`LOC131016067`
原始查询	`SmilChr03G002949`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	protein EXPORTIN 1A
产物	protein EXPORTIN 1A
Arabidopsis	`AT5G17020` (XPO1A) exportin 1A [Source:NCBI gene (formerly Entrezgene);Acc:831565] identity=86.9; qcov=1; evalue=0; confidence=high
Rice	`Os03g0858100` - identity=83.9; qcov=0.999; evalue=0; confidence=high
GO	GO:0000055 (ribosomal large subunit export from nucleus); GO:0000056 (ribosomal small subunit export from nucleus); GO:0005049 (nuclear export signal receptor activity); GO:0005634 (nucleus); GO:0005737 (cytoplasm); GO:0006611 (protein export from nucleus); GO:0031267 (small GTPase binding)
KEGG	smil03008 (Ribosome biogenesis in eukaryotes - Salvia miltiorrhiza (redroot sage)); smil03013 (Nucleocytoplasmic transport - Salvia miltiorrhiza (redroot sage)); smil03250 (Viral life cycle - HIV-1 - Salvia miltiorrhiza (redroot sage))
Pfam	PF03810 (IBN_N); PF08389 (Xpo1); PF08767 (CRM1_C); PF18777 (CRM1_repeat); PF18784 (CRM1_repeat_2); PF18787 (CRM1_repeat_3)
InterPro	-
eggNOG	-
NR	GeneID:131016067

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057800622.1`
2	Cytoplasm	细胞质	1.00000	`XP_057800622.1`
3	Nucleoplasm	核质	0.80000	`XP_057800622.1`
4	Cytosol	细胞质基质	0.80000	`XP_057800622.1`
5	Nucleus membrane	核膜	0.40000	`XP_057800622.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr3:46214744`	`C`	`T`	EMS_canonical_SNV	stop_gained	1	A8
`Chr3:46214744`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A8
`Chr3:46215898`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B10
`Chr3:46215916`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B10
`Chr3:46216138`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B114
`Chr3:46216240`	`T`	`TA`	1bp_insertion	frameshift_variant	97	A10,A13,A16,A19,A2,A23,A25,A4,B100,B105,B110,B111,B112,B118,B119,B12,B120,B121,B122,B123,B126,B129,B136,B140,B22,B24,B26,B28,B29,B31,B35,B36,B37,B38,B39,B4,B42,B43,B45,B48,B5,B50,B52,B55,B58,B65,B67,B7,B72,B74,B79,B80,B82,B87,B89,B90,B92,B95,B97,B99,C10,C11,C15,C17,C18,C19,C22,C25,C26,C28,C3,C34,C4,C40,C44,C49,C50,C51,C52,C53,C55,C57,C58,C6,C61,C67,C68,C7,C73,C75,C80,C82,C86,D1,D2,D6,D8
`Chr3:46216451`	`CGA`	`C`	2bp_deletion	frameshift_variant	26	A19,A2,A23,B112,B117,B136,B31,B33,B5,B55,B67,B72,B79,B80,B85,B9,B95,C18,C26,C44,C61,C76,C86,C87,D6,D8
`Chr3:46216454`	`A`	`ATT`	2bp_insertion	frameshift_variant	25	A19,A2,A23,B112,B117,B136,B33,B5,B55,B67,B72,B79,B80,B85,B9,B95,C18,C26,C44,C61,C76,C86,C87,D6,D8
`Chr3:46216476`	`A`	`AT`	1bp_insertion	frameshift_variant	2	B136,B5
`Chr3:46216476`	`A`	`AT`	1bp_insertion	CDS_variant	2	B136,B5
`Chr3:46216595`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B130
`Chr3:46217758`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B76,C60,C76

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057800622.1

1074 aa

537

1074

IBN_N

Xpo1

CRM1_repeat

CRM1_repeat_2

CRM1_repeat_3

CRM1_C

PF03810 IBN_N 38-102 aa PF08389 Xpo1 115-258 aa PF18777 CRM1_repeat 337-372 aa PF18784 CRM1_repeat_2 407-474 aa PF18787 CRM1_repeat_3 487-537 aa PF08767 CRM1_C 711-1032 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057800622.1`	Pfam	`PF03810`	IBN_N	Repeat	38	102	9.8e-17	61.4	Importin-beta N-terminal domain
`XP_057800622.1`	Pfam	`PF08389`	Xpo1	Repeat	115	258	4.6e-44	150.8	Exportin 1-like protein
`XP_057800622.1`	Pfam	`PF18777`	CRM1_repeat	Repeat	337	372	1.5e-17	63.6	Chromosome region maintenance or exportin repeat
`XP_057800622.1`	Pfam	`PF18784`	CRM1_repeat_2	Repeat	407	474	8.2e-31	106.2	CRM1 / Exportin repeat 2
`XP_057800622.1`	Pfam	`PF18787`	CRM1_repeat_3	Repeat	487	537	1.8e-27	95.8	CRM1 / Exportin repeat 3
`XP_057800622.1`	Pfam	`PF08767`	CRM1_C	Repeat	711	1032	3e-132	441.4	CRM1 C terminal

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XR_009098839.1
CAAGTACACTCTTCCATCTCTCTCTCTAACCATATAAAACGGGAGGGAAGCCTAAAACAATTTTCAAAGTCTCTCTCTCTCTCTAAAACCCCTTCTGCTTTGAATTGAAGCTGTCTTTTCTCATTCTGAATCATCTCTCTCTCTCTCTCTATATATATATATATATATCCCTCTCTACTATCGTTATTTTATCTCTGCACGAGCTCTCCGACCACTGAGACTAGGGTTTGCTCTACTTCCGTTATCGTACAGTCGTGCGC...

XR_009098838.1
CAAGTACACTCTTCCATCTCTCTCTCTAACCATATAAAACGGGAGGGAAGCCTAAAACAATTTTCAAAGTCTCTCTCTCTCTCTAAAACCCCTTCTGCTTTGAATTGAAGCTGTCTTTTCTCATTCTGAATCATCTCTCTCTCTCTCTCTATATATATATATATATATCCCTCTCTACTATCGTTATTTTATCTCTGCACGAGCTCTCCGACCACTGAGACTAGGGTTTGCTCTACTTCCGTTATCGTACAGTCGTGCGC...

CDS

1 records

下载 CDS FASTA

LOC131016067
ATGGCTGCGGAGAAGCTGCGTGATTTAAGTCAGCCGATGGATGTCGCCCTGCTCGACGCCACCGTCGCCGCTTTCTATGGGACCGGATCCAAAGAGGAGAGGACGGCTGCAGACCATATCCTACGGGATTTGCAAAATAATCCAGATATGTGGCTTCAAGTGGTTCACATACTATCTAGTGCACAGAATTTGAATACCAAGTTTTTTGCTTTACAGGTTCTAGAAGGTGTTATTAAATATAGATGGAATGCGTTACCAGT...

Protein

1 records

下载 Protein FASTA

XP_057800622.1
MAAEKLRDLSQPMDVALLDATVAAFYGTGSKEERTAADHILRDLQNNPDMWLQVVHILSSAQNLNTKFFALQVLEGVIKYRWNALPVEQRDGMKNYISEVIVKLSSDEISFRRERLYVNKLNIILVQILKHEWPARWRSFIPDLVAAAKTSETICENCMAILKLLSEEVFDFSRGEMTQQKIKELKQSLNSEFQLIHELCLYVLSASQRAELIRATLATLHAFLSWIPLGYIFESPLLETLLNFFPVPAYRNLTLQCLTE...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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