Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr03G003107`

染色体: Chr03 坐标: 48206575-48209756 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr03G003107`
名称	SmilChr03G003107
描述	COMPASS-like H3K4 histone methylase component WDR5B
染色体 / SeqID	Chr03 / NC_080389.1
坐标与链方向	48206575 - 48209756 / `+`

ID 对照

NCBI Gene ID	`LOC131016253`
GeneID	`131016253`
locus_tag	`-`
NCBI Name	`LOC131016253`
原始查询	`SmilChr03G003107`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	COMPASS-like H3K4 histone methylase component WDR5B
产物	COMPASS-like H3K4 histone methylase component WDR5B
Arabidopsis	`AT4G02730` (WDR5b) Transducin/WD40 repeat-like superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:828189] identity=56.1; qcov=1.17; evalue=7.16e-113; confidence=high
Rice	`Os07g0572000` (OsWDR5b) - identity=48.7; qcov=1.3; evalue=5.92e-102; confidence=high
GO	GO:0042393 (histone binding); GO:0048188 (Set1C/COMPASS complex); GO:0051568 (GO:0051568)
KEGG	smil03083 (Polycomb repressive complex - Salvia miltiorrhiza (redroot sage))
Pfam	PF00400 (WD40); PF08662 (eIF2A); PF25175 (Beta-prop_WDR5)
InterPro	-
eggNOG	-
NR	GeneID:131016253

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057800889.1`
2	Cytoplasm	细胞质	0.40000	`XP_057800890.1`
3	Chromosome	染色体	0.20000	`XP_057800889.1`
4	Nucleolus	核仁	0.20000	`XP_057800890.1`
5	Centromere	着丝粒	0.00000	`XP_057800889.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr3:48206713`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B27,B75,C33,C55
`Chr3:48206953`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B27,B75,C33,C55
`Chr3:48207211`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B135
`Chr3:48207349`	`T`	`TAA`	2bp_insertion	CDS_variant	3	B71,B92,D10
`Chr3:48207899`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B27,B75,C33,C55

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057800889.1

310 aa

155

310

WD40

Beta-prop_WDR5

WD40

eIF2A

WD40

eIF2A

WD40

PF00400 WD40 16-51 aa PF25175 Beta-prop_WDR5 19-307 aa PF00400 WD40 57-92 aa PF08662 eIF2A 65-176 aa PF00400 WD40 98-135 aa PF08662 eIF2A 110-221 aa PF00400 WD40 139-176 aa PF00400 WD40 184-220 aa PF00400 WD40 224-265 aa PF00400 WD40 268-307 aa

XP_057800890.1

259 aa

130

259

WD40

Beta-prop_WDR5

WD40

eIF2A

WD40

PF00400 WD40 16-51 aa PF25175 Beta-prop_WDR5 19-216 aa PF00400 WD40 57-92 aa PF08662 eIF2A 64-176 aa PF00400 WD40 98-135 aa PF00400 WD40 139-176 aa PF00400 WD40 217-256 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057800889.1`	Pfam	`PF00400`	WD40	Repeat	16	51	3.9e-67	220.6	WD domain, G-beta repeat
`XP_057800889.1`	Pfam	`PF25175`	Beta-prop_WDR5	Repeat	19	307	5.8e-125	417.1	WDR5 beta-propeller domain
`XP_057800889.1`	Pfam	`PF00400`	WD40	Repeat	57	92	3.9e-67	220.6	WD domain, G-beta repeat
`XP_057800889.1`	Pfam	`PF08662`	eIF2A	Repeat	65	176	1.3e-13	52.0	Eukaryotic translation initiation factor eIF2A
`XP_057800889.1`	Pfam	`PF00400`	WD40	Repeat	98	135	3.9e-67	220.6	WD domain, G-beta repeat
`XP_057800889.1`	Pfam	`PF08662`	eIF2A	Repeat	110	221	1.3e-13	52.0	Eukaryotic translation initiation factor eIF2A
`XP_057800889.1`	Pfam	`PF00400`	WD40	Repeat	139	176	3.9e-67	220.6	WD domain, G-beta repeat
`XP_057800889.1`	Pfam	`PF00400`	WD40	Repeat	184	220	3.9e-67	220.6	WD domain, G-beta repeat
`XP_057800889.1`	Pfam	`PF00400`	WD40	Repeat	224	265	3.9e-67	220.6	WD domain, G-beta repeat
`XP_057800889.1`	Pfam	`PF00400`	WD40	Repeat	268	307	3.9e-67	220.6	WD domain, G-beta repeat
`XP_057800890.1`	Pfam	`PF00400`	WD40	Repeat	16	51	1.2e-55	184.2	WD domain, G-beta repeat
`XP_057800890.1`	Pfam	`PF25175`	Beta-prop_WDR5	Repeat	19	216	3.9e-96	322.5	WDR5 beta-propeller domain
`XP_057800890.1`	Pfam	`PF00400`	WD40	Repeat	57	92	1.2e-55	184.2	WD domain, G-beta repeat
`XP_057800890.1`	Pfam	`PF08662`	eIF2A	Repeat	64	176	9.4e-09	36.2	Eukaryotic translation initiation factor eIF2A
`XP_057800890.1`	Pfam	`PF00400`	WD40	Repeat	98	135	1.2e-55	184.2	WD domain, G-beta repeat
`XP_057800890.1`	Pfam	`PF00400`	WD40	Repeat	139	176	1.2e-55	184.2	WD domain, G-beta repeat
`XP_057800890.1`	Pfam	`PF00400`	WD40	Repeat	217	256	1.2e-55	184.2	WD domain, G-beta repeat

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057944906.1
AAAAGGGGGGAAATTGGGTGAGGAAGTTGCCTATGTAATGAATTTTTTTTTATTAAATTGACAAACATAGTCTAAGTTGGGTATATATAGAGCAAATTGGGTGCGAGCCGATGGTTTGACGGCAGCCATGTCCAACAGCCAGCCGGCGGCGGCGCACAGCCCCTACCGCCTAAAGAAGATCCTAAGCAAGCACGCACTCTCCGTATCCTGCGTCAAATTCTCCAACGATGGCGGCTTCTTCGCCTCCGCCTCCCTGGACA...

XM_057944907.1
AAAAGGGGGGAAATTGGGTGAGGAAGTTGCCTATGTAATGAATTTTTTTTTATTAAATTGACAAACATAGTCTAAGTTGGGTATATATAGAGCAAATTGGGTGCGAGCCGATGGTTTGACGGCAGCCATGTCCAACAGCCAGCCGGCGGCGGCGCACAGCCCCTACCGCCTAAAGAAGATCCTAAGCAAGCACGCACTCTCCGTATCCTGCGTCAAATTCTCCAACGATGGCGGCTTCTTCGCCTCCGCCTCCCTGGACA...

CDS

2 records

下载 CDS FASTA

LOC131016253
ATGTCCAACAGCCAGCCGGCGGCGGCGCACAGCCCCTACCGCCTAAAGAAGATCCTAAGCAAGCACGCACTCTCCGTATCCTGCGTCAAATTCTCCAACGATGGCGGCTTCTTCGCCTCCGCCTCCCTGGACAAAACCCTAATCGTCTATTCCACAGAAACCCTAACTCAAATCTCGCACTTAATCGGCCATTCGGAGGGCATCAGTGACCTCGCCTGGTCCTCCGACTCCACCTACATCTGCTCCGCCTCCGACGACCG...

Protein

2 records

下载 Protein FASTA

XP_057800889.1
MSNSQPAAAHSPYRLKKILSKHALSVSCVKFSNDGGFFASASLDKTLIVYSTETLTQISHLIGHSEGISDLAWSSDSTYICSASDDRTLRIWLVRAAECVKTLKGHTDRVFCVNFNPQSNLIVSGAFDDTVRLWDVKTGKAVHVIRAHTMPVTSAHFNRDGSLIVSGSHDGSCKIWATATGSLLKTLIDDKVPAVSFAKFSPNGKFILVATLDDTLKLWNYSNGKFIKIYTGHANRVYCITPTFSVSGDKLIVSGSEDNC...

XP_057800890.1
MSNSQPAAAHSPYRLKKILSKHALSVSCVKFSNDGGFFASASLDKTLIVYSTETLTQISHLIGHSEGISDLAWSSDSTYICSASDDRTLRIWLVRAAECVKTLKGHTDRVFCVNFNPQSNLIVSGAFDDTVRLWDVKTGKAVHVIRAHTMPVTSAHFNRDGSLIVSGSHDGSCKIWATATGSLLKTLIDDKVPAVSFAKFSPNGKFILVATLDDTLGKLLQKLEGHTDTVISVTCHPTVNMIVSAGLEKDKTVRVWVQE

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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