Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr03G003909`

染色体: Chr03 坐标: 58174378-58182999 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr03G003909`
名称	SmilChr03G003909
描述	dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex, mitochondrial
染色体 / SeqID	Chr03 / NC_080389.1
坐标与链方向	58174378 - 58182999 / `-`

ID 对照

NCBI Gene ID	`LOC131014763`
GeneID	`131014763`
locus_tag	`-`
NCBI Name	`LOC131014763`
原始查询	`SmilChr03G003909`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex, mitochondrial
产物	dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex%2C mitochondrial
Arabidopsis	`AT3G52200` (LTA3) Dihydrolipoamide acetyltransferase, long form protein [Source:NCBI gene (formerly Entrezgene);Acc:824385] identity=69.7; qcov=1.01; evalue=0; confidence=high
Rice	`Os06g0499900` - identity=67.2; qcov=0.832; evalue=0; confidence=high
GO	GO:0005739 (mitochondrion); GO:0006086 (pyruvate decarboxylation to acetyl-CoA); GO:0016746 (acyltransferase activity); GO:0045254 (pyruvate dehydrogenase complex)
KEGG	smil00010 (Glycolysis / Gluconeogenesis - Salvia miltiorrhiza (redroot sage)); smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil00785 (Lipoic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00198 (2-oxoacid_dh); PF00364 (Biotin_lipoyl); PF02817 (E3_binding)
InterPro	-
eggNOG	-
NR	GeneID:131014763

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057798833.1`
2	Cytosol	细胞质基质	1.00000	`XP_057798834.1`
3	Cytoplasm	细胞质	0.80000	`XP_057798834.1`
4	Mitochondrion matrix	线粒体基质	0.40000	`XP_057798833.1`
5	Chloroplast	叶绿体	0.40000	`XP_057798833.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr3:58175476`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B25,B35,C76
`Chr3:58175512`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A21
`Chr3:58175832`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B65,B95,C50
`Chr3:58175986`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B24
`Chr3:58177761`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr3:58177917`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B42,D11
`Chr3:58179164`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C13
`Chr3:58181909`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B111,B51,B68

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057798833.1

635 aa

318

635

Biotin_lipoyl

E3_binding

2-oxoacid_dh

PF00364 Biotin_lipoyl 86-157 aa PF00364 Biotin_lipoyl 213-283 aa PF02817 E3_binding 327-361 aa PF00198 2-oxoacid_dh 405-634 aa

XP_057798834.1

531 aa

266

531

Biotin_lipoyl

E3_binding

2-oxoacid_dh

PF00364 Biotin_lipoyl 1-53 aa PF00364 Biotin_lipoyl 109-179 aa PF02817 E3_binding 223-257 aa PF00198 2-oxoacid_dh 301-530 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057798833.1`	Pfam	`PF00364`	Biotin_lipoyl	Domain	86	157	1.8e-35	121.3	Biotin-requiring enzyme
`XP_057798833.1`	Pfam	`PF00364`	Biotin_lipoyl	Domain	213	283	1.8e-35	121.3	Biotin-requiring enzyme
`XP_057798833.1`	Pfam	`PF02817`	E3_binding	Family	327	361	7.3e-09	36.4	e3 binding domain
`XP_057798833.1`	Pfam	`PF00198`	2-oxoacid_dh	Domain	405	634	3.6e-73	246.6	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
`XP_057798834.1`	Pfam	`PF00364`	Biotin_lipoyl	Domain	1	53	5.4e-30	103.8	Biotin-requiring enzyme
`XP_057798834.1`	Pfam	`PF00364`	Biotin_lipoyl	Domain	109	179	5.4e-30	103.8	Biotin-requiring enzyme
`XP_057798834.1`	Pfam	`PF02817`	E3_binding	Family	223	257	5.4e-09	36.8	e3 binding domain
`XP_057798834.1`	Pfam	`PF00198`	2-oxoacid_dh	Domain	301	530	2.5e-73	247.1	2-oxoacid dehydrogenases acyltransferase (catalytic domain)

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057942850.1
GAGAAAGCAAAAAAGAAAAAGAAGGTACAGCACGAATTCGTCTTCCTTGTTTGTGCGTACGTAGAAATTACTATATTTAATTACAGAAAGGGAAGTAGGAAAAAGGTGAATTTGCTGCGAATTTGATCTATGGCGCTGTCGAGGCTACGGCATCCGGTGATCTCGCGTGCTCCGTCTCTCATCAGAGCTCGCTTCCTCTCTCTCTCATCTGCTCATTCATTTCTCAATCGTTCAAGGGGGCTGGATTCAAGTCCTGAAGT...

XM_057942851.1
CTCCTTTTCGTCTGCTGAGATGCCTGAGCATACAGTGCTTCAAATGCCAGCTTTGTCACCTACAATGGTAACGAACTAGTCAAGGTAATATTGTGAAGTGGATGAAGAAAGAGGGAGATAAGATTGAAGTGGGGGATGTGCTTTGTGAAATCGAGACAGACAAAGCCACTGTGGAGTTTGAATCTCTTGAAGAAGGGTTTCTGGCCAAGATACTGGTGCCTGAAGGTTCAAAGGATGTTCCTGTGGGACAGTCTATAGCT...

CDS

2 records

下载 CDS FASTA

LOC131014763
ATGGCGCTGTCGAGGCTACGGCATCCGGTGATCTCGCGTGCTCCGTCTCTCATCAGAGCTCGCTTCCTCTCTCTCTCATCTGCTCATTCATTTCTCAATCGTTCAAGGGGGCTGGATTCAAGTCCTGAAGTTGCAGAGACGTTGTTAAGGCCAACATCATTTCCATTAGTTAATGGCATTCATGGTGATTCTTCTAAGAAAAAGTTCAATATCGGTATCCGCTCCTTTTCGTCTGCTGAGATGCCTGAGCATACAGTGCT...

LOC131014763
ATGAAGAAAGAGGGAGATAAGATTGAAGTGGGGGATGTGCTTTGTGAAATCGAGACAGACAAAGCCACTGTGGAGTTTGAATCTCTTGAAGAAGGGTTTCTGGCCAAGATACTGGTGCCTGAAGGTTCAAAGGATGTTCCTGTGGGACAGTCTATAGCTATTACAGTTGAGGATCGAGATGATATAGGTAGCATTCCTGCAACTGTAAGTGGGACAGAAGCTGCAGATAAAACTTCCACTGAACCAGCAGCGAAACATGG...

Protein

2 records

下载 Protein FASTA

XP_057798833.1
MALSRLRHPVISRAPSLIRARFLSLSSAHSFLNRSRGLDSSPEVAETLLRPTSFPLVNGIHGDSSKKKFNIGIRSFSSAEMPEHTVLQMPALSPTMSQGNIVKWMKKEGDKIEVGDVLCEIETDKATVEFESLEEGFLAKILVPEGSKDVPVGQSIAITVEDRDDIGSIPATVSGTEAADKTSTEPAAKHGDNTQESSSVNINTSELPPHIVLEMPALSPTMNQGNIAKWMKKEGDKIEVGDVICEIETDKATVEYECLE...

XP_057798834.1
MKKEGDKIEVGDVLCEIETDKATVEFESLEEGFLAKILVPEGSKDVPVGQSIAITVEDRDDIGSIPATVSGTEAADKTSTEPAAKHGDNTQESSSVNINTSELPPHIVLEMPALSPTMNQGNIAKWMKKEGDKIEVGDVICEIETDKATVEYECLEEGFLAKILAPEGSRDVAVGQPIAITVEDSNDLEAVRTSVSTDVKTKNEKPVQKIAKDVKTQKTNFSRISPAAKMLISEHGLDASSITSSGPRGTLLKGDVLAAI...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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