Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr03G004100`

染色体: Chr03 坐标: 59886470-59902314 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr03G004100`
名称	SmilChr03G004100
描述	ATP-dependent DNA helicase Q-like 2
染色体 / SeqID	Chr03 / NC_080389.1
坐标与链方向	59886470 - 59902314 / `+`

ID 对照

NCBI Gene ID	`LOC131014965`
GeneID	`131014965`
locus_tag	`-`
NCBI Name	`LOC131014965`
原始查询	`SmilChr03G004100`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	ATP-dependent DNA helicase Q-like 2
产物	ATP-dependent DNA helicase Q-like 2
Arabidopsis	`AT1G31360` (RECQL2) RECQ helicase L2 [Source:NCBI gene (formerly Entrezgene);Acc:840026] identity=73.9; qcov=0.933; evalue=0; confidence=high
Rice	`Os11g0708600` (OsMed34_2) - identity=78.6; qcov=0.812; evalue=0; confidence=high
GO	GO:0000724 (double-strand break repair via homologous recombination); GO:0003676 (nucleic acid binding); GO:0005524 (ATP binding); GO:0005694 (chromosome); GO:0005737 (cytoplasm); GO:0006268 (GO:0006268); GO:0009378 (four-way junction helicase activity); GO:0016592 (mediator complex); GO:0043138 (3'-5' DNA helicase activity)
KEGG	-
Pfam	PF00270 (DEAD); PF00271 (Helicase_C); PF00570 (HRDC); PF04851 (ResIII); PF16124 (RecQ_Zn_bind)
InterPro	-
eggNOG	-
NR	GeneID:131014965

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057799121.1`
2	Nucleoplasm	核质	1.00000	`XP_057799121.1`
3	Cytosol	细胞质基质	0.80000	`XP_057799124.1`
4	Cytoplasm	细胞质	0.60000	`XP_057799124.1`
5	Nuclear body	核内小体	0.40000	`XP_057799123.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr3:59893992`	`AC`	`A`	1bp_deletion	frameshift_variant	1	B94
`Chr3:59893992`	`AC`	`A`	1bp_deletion	CDS_variant	1	B94
`Chr3:59893993`	`C`	`T`	EMS_canonical_SNV	stop_gained	51	A11,A19,A20,A24,B100,B102,B106,B11,B110,B124,B131,B132,B134,B16,B17,B2,B26,B30,B32,B42,B43,B50,B51,B58,B68,B73,B79,B83,B84,B89,B97,B98,C12,C17,C20,C29,C33,C41,C48,C49,C5,C50,C51,C52,C55,C65,C75,C8,C82,D5,D7
`Chr3:59893997`	`GA`	`G`	1bp_deletion	frameshift_variant	34	A14,A25,A9,B1,B104,B111,B127,B132,B135,B35,B36,B46,B48,B55,B65,B7,B75,B76,B78,B87,B91,C13,C15,C2,C21,C26,C29,C37,C4,C50,C7,C71,C82,C87
`Chr3:59894013`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B56,B96
`Chr3:59894024`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C42,C60
`Chr3:59894033`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	C32,C68,D9
`Chr3:59894045`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B33,B64,C39,C56
`Chr3:59894086`	`GA`	`G`	1bp_deletion	frameshift_variant	3	C32,C68,D9
`Chr3:59894086`	`GA`	`G`	1bp_deletion	CDS_variant	3	C32,C68,D9
`Chr3:59894644`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr3:59894683`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	D10,D11

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057799121.1

673 aa

336

673

ResIII

DEAD

RecQ_Zn_bind

HRDC

PF04851 ResIII 91-255 aa PF00270 DEAD 92-261 aa PF16124 RecQ_Zn_bind 395-450 aa PF00570 HRDC 580-640 aa

XP_057799123.1

698 aa

349

698

ResIII

DEAD

Helicase_C

RecQ_Zn_bind

HRDC

PF04851 ResIII 91-255 aa PF00270 DEAD 92-261 aa PF00271 Helicase_C 305-408 aa PF16124 RecQ_Zn_bind 420-475 aa PF00570 HRDC 605-665 aa

XP_057799124.1

600 aa

300

600

ResIII

DEAD

Helicase_C

RecQ_Zn_bind

PF04851 ResIII 129-293 aa PF00270 DEAD 130-299 aa PF00271 Helicase_C 343-446 aa PF16124 RecQ_Zn_bind 458-513 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057799121.1`	Pfam	`PF04851`	ResIII	Family	91	255	3.6e-06	27.7	Type III restriction enzyme, res subunit
`XP_057799121.1`	Pfam	`PF00270`	DEAD	Domain	92	261	2.5e-25	89.8	DEAD/DEAH box helicase
`XP_057799121.1`	Pfam	`PF16124`	RecQ_Zn_bind	Domain	395	450	2.4e-10	41.7	RecQ zinc-binding
`XP_057799121.1`	Pfam	`PF00570`	HRDC	Domain	580	640	1.1e-08	35.6	HRDC domain
`XP_057799123.1`	Pfam	`PF04851`	ResIII	Family	91	255	4e-06	27.5	Type III restriction enzyme, res subunit
`XP_057799123.1`	Pfam	`PF00270`	DEAD	Domain	92	261	4.3e-26	92.3	DEAD/DEAH box helicase
`XP_057799123.1`	Pfam	`PF00271`	Helicase_C	Domain	305	408	2e-21	77.0	Helicase conserved C-terminal domain
`XP_057799123.1`	Pfam	`PF16124`	RecQ_Zn_bind	Domain	420	475	2.6e-10	41.6	RecQ zinc-binding
`XP_057799123.1`	Pfam	`PF00570`	HRDC	Domain	605	665	1.2e-08	35.5	HRDC domain
`XP_057799124.1`	Pfam	`PF04851`	ResIII	Family	129	293	3e-06	28.0	Type III restriction enzyme, res subunit
`XP_057799124.1`	Pfam	`PF00270`	DEAD	Domain	130	299	3.7e-26	92.6	DEAD/DEAH box helicase
`XP_057799124.1`	Pfam	`PF00271`	Helicase_C	Domain	343	446	1.3e-21	77.6	Helicase conserved C-terminal domain
`XP_057799124.1`	Pfam	`PF16124`	RecQ_Zn_bind	Domain	458	513	2.1e-10	41.9	RecQ zinc-binding

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057943141.1
TTGGAGATGCTCTCATATGAAAATACAGAGAAGCGGAAAATTCGCGGCGAAACAGAGAAAGATTTCGGTTTCGGTGTGTTTTGAGAACTTCGTTCACTTATCCACGAAAATTAGTACTGAAAAAAGTGAAATGGGAACAACAGAAGAAATTTTAACGGAGCTTCTCGGCGTTGAAATGGAGCTTCAGGATGTTCAAGAGCAAATAAAGGCGTTGCTCGAACAACAAGAAAATCTGCACGAGAGGCAATCCGAACTAAAAG...

XM_057943140.1
GGATTTGAATTGGAGGGCCCAATAAGCATTATGTTCTTCAATTTCACCTCCTTTTTATTCAGCAGAAAATACAGAGAAGCGGAAAATTCGCGGCGAAACAGAGAAAGATTTCGGTTTCGGTGTGTTTTGAGAACTTCGTTCACTTATCCACGAAAATTAGTACTGAAAAAAGTGAAATGGGAACAACAGAAGAAATTTTAACGGAGCTTCTCGGCGTTGAAATGGAGCTTCAGGATGTTCAAGAGCAAATAAAGGCGTTG...

CDS

3 records

下载 CDS FASTA

LOC131014965
ATGAAAATACAGAGAAGCGGAAAATTCGCGGCGAAACAGAGAAAGATTTCGGTTTCGGTGTGTTTTGAGAACTTCGTTCACTTATCCACGAAAATTAGTACTGAAAAAAGTGAAATGGGAACAACAGAAGAAATTTTAACGGAGCTTCTCGGCGTTGAAATGGAGCTTCAGGATGTTCAAGAGCAAATAAAGGCGTTGCTCGAACAACAAGAAAATCTGCACGAGAGGCAATCCGAACTAAAAGCTCTGCTGGAACATAA...

LOC131014965
ATGGGAACAACAGAAGAAATTTTAACGGAGCTTCTCGGCGTTGAAATGGAGCTTCAGGATGTTCAAGAGCAAATAAAGGCGTTGCTCGAACAACAAGAAAATCTGCACGAGAGGCAATCCGAACTAAAAGCTCTGCTGGAACATAACGAGTCATCTAGAAGCCATGGGGGAGATGAAGCTTCTGTTTCTGTGGAGAACTGGTCTGGGTCATTTGAATGGGATTCTCAAGCTGATGATGTTAGGCTAAATATCTTTGGGAT...

Protein

3 records

下载 Protein FASTA

XP_057799121.1
MGTTEEILTELLGVEMELQDVQEQIKALLEQQENLHERQSELKALLEHNESSRSHGGDEASVSVENWSGSFEWDSQADDVRLNIFGISAYRANQREILNAIMSRRDVLVIMAAGGGKSLCYQLPAVLREGVALVVSPLLSLIQDQVMGLAALGIKAFMLTSTTNKEDEKFIYKALEKGEGELKILYVTPEKISKSKRFMSKLEKCHHAGRLSLISIDEAHCCSQWGHDFRPDYRNLGILKTQFPDVPMVALTATATKKVQ...

XP_057799123.1
MGTTEEILTELLGVEMELQDVQEQIKALLEQQENLHERQSELKALLEHNESSRSHGGDEASVSVENWSGSFEWDSQADDVRLNIFGISAYRANQREILNAIMSRRDVLVIMAAGGGKSLCYQLPAVLREGVALVVSPLLSLIQDQVMGLAALGIKAFMLTSTTNKEDEKFIYKALEKGEGELKILYVTPEKISKSKRFMSKLEKCHHAGRLSLISIDEAHCCSQWGHDFRPDYRNLGILKTQFPDVPMVALTATATKKVQ...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器