Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr03G004642`

染色体: Chr03 坐标: 64002956-64005634 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr03G004642`
名称	SmilChr03G004642
描述	(S)-coclaurine N-methyltransferase
染色体 / SeqID	Chr03 / NC_080389.1
坐标与链方向	64002956 - 64005634 / `-`

ID 对照

NCBI Gene ID	`LOC131015404`
GeneID	`131015404`
locus_tag	`-`
NCBI Name	`LOC131015404`
原始查询	`SmilChr03G004642`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	(S)-coclaurine N-methyltransferase
产物	(S)-coclaurine N-methyltransferase
Arabidopsis	`AT4G33110` (AT4G33110) S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:829448] identity=73; qcov=0.978; evalue=0; confidence=high
Rice	`Os06g0574100` - identity=78.3; qcov=0.229; evalue=9.11e-45; confidence=weak
GO	-
KEGG	-
Pfam	PF01135 (PCMT); PF02353 (CMAS); PF02390 (Methyltransf_4); PF03848 (TehB); PF05175 (MTS); PF08241 (Methyltransf_11); PF08242 (Methyltransf_12); PF13489 (Methyltransf_23); PF13649 (Methyltransf_25); PF13847 (Methyltransf_31)
InterPro	-
eggNOG	-
NR	GeneID:131015404

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Endoplasmic reticulum	内质网	0.80000	`XP_057799769.1`
2	Endoplasmic reticulum membrane	内质网膜	0.40000	`XP_057799769.1`
3	Cytosol	细胞质基质	0.20000	`XP_057799769.1`
4	Peroxisome	过氧化物酶体	0.20000	`XP_057799769.1`
5	Nucleus	细胞核	0.00000	`XP_057799769.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr3:64003190`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B49,B76,B79,C85
`Chr3:64003254`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B57,B86,C46,C74
`Chr3:64003272`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	C1,C17,C31,C4,C49
`Chr3:64003987`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B48
`Chr3:64004266`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D2
`Chr3:64004342`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	C1,C17,C31,C4,C49
`Chr3:64004382`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B21,C37
`Chr3:64004390`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B35,B36,B37,C20
`Chr3:64004716`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A23,B114,C16,C70,C87
`Chr3:64004751`	`G`	`GAT`	2bp_insertion	frameshift_variant	3	C1,C17,C49
`Chr3:64004751`	`G`	`GAT`	2bp_insertion	CDS_variant	3	C1,C17,C49
`Chr3:64005306`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B17,C13,C28

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057799769.1

363 aa

182

363

CMAS

PCMT

MTS

Methyltransf_23

Methyltransf_31

Methyltransf_4

TehB

Methyltransf_25

Methyltransf_12

Methyltransf_11

PF02353 CMAS 85-318 aa PF01135 PCMT 125-209 aa PF05175 MTS 136-210 aa PF13489 Methyltransf_23 136-244 aa PF13847 Methyltransf_31 136-255 aa PF02390 Methyltransf_4 140-197 aa PF03848 TehB 140-229 aa PF13649 Methyltransf_25 141-234 aa PF08242 Methyltransf_12 142-236 aa PF08241 Methyltransf_11 142-238 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057799769.1`	Pfam	`PF02353`	CMAS	Family	85	318	1.9e-43	149.5	Mycolic acid cyclopropane synthetase
`XP_057799769.1`	Pfam	`PF01135`	PCMT	Family	125	209	3.9e-05	24.2	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
`XP_057799769.1`	Pfam	`PF05175`	MTS	Domain	136	210	9.4e-07	29.3	Methyltransferase small domain
`XP_057799769.1`	Pfam	`PF13489`	Methyltransf_23	Domain	136	244	1.1e-13	51.9	Methyltransferase domain
`XP_057799769.1`	Pfam	`PF13847`	Methyltransf_31	Domain	136	255	3.2e-16	60.2	Methyltransferase domain
`XP_057799769.1`	Pfam	`PF02390`	Methyltransf_4	Family	140	197	4.6e-06	26.9	Putative methyltransferase
`XP_057799769.1`	Pfam	`PF03848`	TehB	Family	140	229	4.1e-05	23.8	Tellurite resistance protein TehB
`XP_057799769.1`	Pfam	`PF13649`	Methyltransf_25	Domain	141	234	1.2e-16	61.9	Methyltransferase domain
`XP_057799769.1`	Pfam	`PF08242`	Methyltransf_12	Domain	142	236	9.6e-12	46.2	Methyltransferase domain
`XP_057799769.1`	Pfam	`PF08241`	Methyltransf_11	Domain	142	238	2.3e-15	57.7	Methyltransferase domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057943786.1
CATATAAAATAAAATAAAATAATGATGTGTGCATAATAAAACAAGTGGTCTATTCCAGTCACGTCGCTAAACAGATTAGATAACGAGATAAATCGGAAAGCTTCACTCCTTCCTTCCTCAATTAAATTTTCCGGCAATGGCGGCGGCGAACGGCGGCGTTGTCGATTCGATCGTGCATGCGCCCTACGCCGCTACAGTCCGCGTGATGCTCGCTTCACTTGAGCGGAATTTGCTGCCGGACGCCGTCGTGCGCCGCCTCA...

CDS

1 records

下载 CDS FASTA

LOC131015404
ATGGCGGCGGCGAACGGCGGCGTTGTCGATTCGATCGTGCATGCGCCCTACGCCGCTACAGTCCGCGTGATGCTCGCTTCACTTGAGCGGAATTTGCTGCCGGACGCCGTCGTGCGCCGCCTCACGCGGCTGCTGCTCGCGAGCCGCCTCCGCTCCGGTTACCGACCGTCAGCTGAAATTCAGCTCTCCGATCTCATACACTTCGCGCATTCTTTGAGAGAGATGCCGATAGCAATCAAGACAGAAGAGCCCAAGTATCA...

Protein

1 records

下载 Protein FASTA

XP_057799769.1
MAAANGGVVDSIVHAPYAATVRVMLASLERNLLPDAVVRRLTRLLLASRLRSGYRPSAEIQLSDLIHFAHSLREMPIAIKTEEPKYQHYEVPTSFFKLVLGKHLKYSCCFFPDKSSTLEDAEKAMLELYCERSQMKDGYSVLDVGCGWGSLSLYLAQKYPNSQITGICNSTTQKSHIEEQCRDLELQNVEIIVADISTFEMEASYDRIFSIEMFEHMKNYHDLLKKISRWMKPDSLLFVHYFCHKAFAYHFEDVNDDDWI...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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