Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr03G004752`

染色体: Chr03 坐标: 64596683-64601942 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr03G004752`
名称	SmilChr03G004752
描述	chaperone protein ClpB4, mitochondrial
染色体 / SeqID	Chr03 / NC_080389.1
坐标与链方向	64596683 - 64601942 / `-`

ID 对照

NCBI Gene ID	`LOC131015599`
GeneID	`131015599`
locus_tag	`-`
NCBI Name	`LOC131015599`
原始查询	`SmilChr03G004752`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	chaperone protein ClpB4, mitochondrial
产物	chaperone protein ClpB4%2C mitochondrial
Arabidopsis	`AT2G25140` (CLPB4) casein lytic proteinase B4 [Source:NCBI gene (formerly Entrezgene);Acc:817052] identity=78.2; qcov=0.937; evalue=0; confidence=high
Rice	`Os02g0181900` (ClpB-m) - identity=77.8; qcov=0.927; evalue=0; confidence=high
GO	GO:0005524 (ATP binding); GO:0005737 (cytoplasm); GO:0016887 (ATP hydrolysis activity); GO:0034605 (cellular response to heat); GO:0042026 (protein refolding)
KEGG	-
Pfam	PF00004 (AAA); PF00158 (Sigma54_activat); PF02861 (Clp_N); PF07724 (AAA_2); PF07728 (AAA_5); PF10431 (ClpB_D2-small); PF17871 (AAA_lid_9)
InterPro	-
eggNOG	-
NR	GeneID:131015599

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057800016.1`
2	Nucleus	细胞核	0.00000	`XP_057800016.1`
3	Chromosome	染色体	0.00000	`XP_057800016.1`
4	Centromere	着丝粒	0.00000	`XP_057800016.1`
5	Chromatin	染色质	0.00000	`XP_057800016.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr3:64596906`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B118,B95
`Chr3:64596949`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A22,B1,B110,D8
`Chr3:64597011`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr3:64597119`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B99
`Chr3:64597566`	`C`	`CA`	1bp_insertion	frameshift_variant	1	A2
`Chr3:64597566`	`C`	`CA`	1bp_insertion	CDS_variant	1	A2
`Chr3:64597570`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B41,B49,B50,C9
`Chr3:64597597`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B15,B56,B74,B96
`Chr3:64597659`	`GC`	`G`	1bp_deletion	frameshift_variant	28	A10,A20,B102,B105,B123,B125,B131,B132,B14,B25,B28,B36,B40,B55,B60,B72,B89,B98,C33,C42,C55,C62,C64,C66,C67,C75,C83,D4
`Chr3:64597864`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B118
`Chr3:64597917`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C32,C68
`Chr3:64598277`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	C23,C26

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057800016.1

969 aa

484

969

Clp_N

AAA

AAA_lid_9

AAA_2

Sigma54_activat

AAA_5

AAA

ClpB_D2-small

PF02861 Clp_N 89-212 aa PF00004 AAA 288-419 aa PF17871 AAA_lid_9 426-528 aa PF07724 AAA_2 684-853 aa PF00158 Sigma54_activat 687-806 aa PF07728 AAA_5 689-810 aa PF00004 AAA 690-807 aa PF10431 ClpB_D2-small 860-939 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057800016.1`	Pfam	`PF02861`	Clp_N	Family	89	212	4.4e-32	111.7	Clp repeat (R) N-terminal domain
`XP_057800016.1`	Pfam	`PF00004`	AAA	Domain	288	419	2.8e-24	86.7	ATPase family associated with various cellular activities (AAA)
`XP_057800016.1`	Pfam	`PF17871`	AAA_lid_9	Domain	426	528	5.2e-34	117.0	AAA lid domain
`XP_057800016.1`	Pfam	`PF07724`	AAA_2	Domain	684	853	7.8e-72	241.4	AAA domain (Cdc48 subfamily)
`XP_057800016.1`	Pfam	`PF00158`	Sigma54_activat	Domain	687	806	3e-09	37.5	Sigma-54 interaction domain
`XP_057800016.1`	Pfam	`PF07728`	AAA_5	Domain	689	810	7.2e-18	65.7	AAA domain (dynein-related subfamily)
`XP_057800016.1`	Pfam	`PF00004`	AAA	Domain	690	807	2.8e-24	86.7	ATPase family associated with various cellular activities (AAA)
`XP_057800016.1`	Pfam	`PF10431`	ClpB_D2-small	Domain	860	939	1.1e-25	90.1	C-terminal, D2-small domain, of ClpB protein

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057944033.1
GTTATAAAAAGATTTCTCTACATTCTTCTGGACTCGGCCGTTTTGCTTTAGCGACGATGGCAATTGTTAGAAGCACGCCGGCGGTGCGGCTAAGCAGGTCAGCCGTCGCAGCGCTTAGGGCAACCGGCAGGGGTCTTCAAACCCTACCAGCATCGTCCCCTGCGCTGCGCTCAGCCTCCGCCTCCCCTGCTTTTTATCCCCGTGCTCCCGTTCCCACCCTCACTAATAACCAAAATACAATTTCTTCTGCTTCGATCTCA...

CDS

1 records

下载 CDS FASTA

LOC131015599
ATGGCAATTGTTAGAAGCACGCCGGCGGTGCGGCTAAGCAGGTCAGCCGTCGCAGCGCTTAGGGCAACCGGCAGGGGTCTTCAAACCCTACCAGCATCGTCCCCTGCGCTGCGCTCAGCCTCCGCCTCCCCTGCTTTTTATCCCCGTGCTCCCGTTCCCACCCTCACTAATAACCAAAATACAATTTCTTCTGCTTCGATCTCATCATCATCATCATGCATCCGCTCTTACTCCTCTGCTGCCTCTAGCCAGATTAGCAA...

Protein

1 records

下载 Protein FASTA

XP_057800016.1
MAIVRSTPAVRLSRSAVAALRATGRGLQTLPASSPALRSASASPAFYPRAPVPTLTNNQNTISSASISSSSSCIRSYSSAASSQISNSEFTEMAWDGILGAVDAAKDSKHQVVETEHLMKALLEQKDGLARRIFTKAGVDNTSLLQSTDDFISQQPKVSGDTTGPIVGSHFTSLLENARKCKKQMGDSFLSVEHLVLAFPSDKRFGQKLLDNLQLSDKALKDAVDAVRGSQRVTDQNPEGKYEALEKYGNDLTELARRGK...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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