Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G000119`

染色体: Chr04 坐标: 1025818-1030720 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G000119`
名称	SmilChr04G000119
描述	ATP-dependent DNA helicase 2 subunit KU80
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	1025818 - 1030720 / `-`

ID 对照

NCBI Gene ID	`LOC131022049`
GeneID	`131022049`
locus_tag	`-`
NCBI Name	`LOC131022049`
原始查询	`SmilChr04G000119`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	ATP-dependent DNA helicase 2 subunit KU80
产物	ATP-dependent DNA helicase 2 subunit KU80
Arabidopsis	`AT1G48050` (KU80) Ku80 family protein [Source:NCBI gene (formerly Entrezgene);Acc:841223] identity=58.5; qcov=0.994; evalue=0; confidence=high
Rice	`Os03g0856200` (OsKu80) - identity=65.4; qcov=0.75; evalue=0; confidence=high
GO	GO:0000723 (telomere maintenance); GO:0003678 (DNA helicase activity); GO:0003684 (damaged DNA binding); GO:0003690 (double-stranded DNA binding); GO:0005634 (nucleus); GO:0006303 (double-strand break repair via nonhomologous end joining); GO:0006310 (DNA recombination); GO:0042162 (telomeric repeat DNA binding); GO:0043564 (Ku70:Ku80 complex); GO:0071480 (cellular response to gamma radiation); GO:0071481 (cellular response to X-ray)
KEGG	smil03450 (Non-homologous end-joining - Salvia miltiorrhiza (redroot sage))
Pfam	PF02735 (Ku); PF03730 (Ku_C); PF03731 (Ku_N); PF08785 (Ku_PK_bind)
InterPro	-
eggNOG	-
NR	GeneID:131022049

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057807403.1`
2	Nucleoplasm	核质	1.00000	`XP_057807403.1`
3	Chromosome	染色体	0.60000	`XP_057807403.1`
4	Nuclear body	核内小体	0.20000	`XP_057807403.1`
5	Centromere	着丝粒	0.00000	`XP_057807403.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:1026040`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr4:1026041`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B101,C10
`Chr4:1026457`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B72
`Chr4:1026463`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B127
`Chr4:1026482`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C42
`Chr4:1026697`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B114
`Chr4:1026911`	`TGG`	`T`	2bp_deletion	frameshift_variant	1	B62
`Chr4:1026911`	`TGG`	`T`	2bp_deletion	CDS_variant	1	B62
`Chr4:1026926`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B121
`Chr4:1027317`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C58
`Chr4:1027342`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C16,C33
`Chr4:1027358`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B117,B33,B49,B91,C8

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057807403.1

690 aa

345

690

Ku_N

Ku_C

Ku_PK_bind

PF03731 Ku_N 8-134 aa PF02735 Ku 228-430 aa PF03730 Ku_C 452-529 aa PF08785 Ku_PK_bind 564-674 aa

XP_057807404.1

689 aa

344

689

Ku_N

Ku_C

Ku_PK_bind

PF03731 Ku_N 8-134 aa PF02735 Ku 228-430 aa PF03730 Ku_C 452-529 aa PF08785 Ku_PK_bind 564-674 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057807403.1`	Pfam	`PF03731`	Ku_N	Domain	8	134	7.8e-09	36.3	Ku70/Ku80 N-terminal alpha/beta domain
`XP_057807403.1`	Pfam	`PF02735`	Ku	Domain	228	430	4.7e-44	151.3	Ku70/Ku80 beta-barrel domain
`XP_057807403.1`	Pfam	`PF03730`	Ku_C	Family	452	529	1.4e-08	35.9	Ku70/Ku80 C-terminal arm
`XP_057807403.1`	Pfam	`PF08785`	Ku_PK_bind	Domain	564	674	3.8e-32	111.7	Ku C terminal domain like
`XP_057807404.1`	Pfam	`PF03731`	Ku_N	Domain	8	134	7.8e-09	36.3	Ku70/Ku80 N-terminal alpha/beta domain
`XP_057807404.1`	Pfam	`PF02735`	Ku	Domain	228	430	4.6e-44	151.3	Ku70/Ku80 beta-barrel domain
`XP_057807404.1`	Pfam	`PF03730`	Ku_C	Family	452	529	1.4e-08	35.9	Ku70/Ku80 C-terminal arm
`XP_057807404.1`	Pfam	`PF08785`	Ku_PK_bind	Domain	564	674	4.5e-33	114.7	Ku C terminal domain like

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057951421.1
GAAATCAAATTCATTTTATTGTTTTGCAAATGTTTATTAAGGAAAAACAAAAAGGAAAATTCTTAGGGAAGCTTTACTCCGCGGGAATGGATGCAAGAGAGTGACAAAACTTCAAACGCCACCGCTTACCTCTTGCCTGTTTCTTTTCTTTCTCCGATTTTAAGCTGTGAAAATGGCTCGAAATAAGGAAGGTCTGGTGCTGGTGATTGAAGTTGGTCCGTCGATGCATGGCGTGCTGCCGGAAGTTGAAAAAGTTTGTT...

XM_057951420.1
GAAATCAAATTCATTTTATTGTTTTGCAAATGTTTATTAAGGAAAAACAAAAAGGAAAATTCTTAGGGAAGCTTTACTCCGCGGGAATGGATGCAAGAGAGTGACAAAACTTCAAACGCCACCGCTTACCTCTTGCCTGTTTCTTTTCTTTCTCCGATTTTAAGCTGTGAAAATGGCTCGAAATAAGGAAGGTCTGGTGCTGGTGATTGAAGTTGGTCCGTCGATGCATGGCGTGCTGCCGGAAGTTGAAAAAGTTTGTT...

CDS

2 records

下载 CDS FASTA

LOC131022049
ATGGCTCGAAATAAGGAAGGTCTGGTGCTGGTGATTGAAGTTGGTCCGTCGATGCATGGCGTGCTGCCGGAAGTTGAAAAAGTTTGTTGTCTGCTTGCGCAGAAGAAGCTGATTTATGGCAAGTATGATGAAGTGGGGGTTGTGGCATTTGGCACTACAGGTACTAAAAATGACTTGACAGTGGAAGTGGGCGGGTACGAGAATGTGACCGTTTTGAGGGATATTAAGGTTGTTGATGGAGATCTTGTGGATGTTCTACA...

Protein

2 records

下载 Protein FASTA

XP_057807403.1
MARNKEGLVLVIEVGPSMHGVLPEVEKVCCLLAQKKLIYGKYDEVGVVAFGTTGTKNDLTVEVGGYENVTVLRDIKVVDGDLVDVLHQLPRGGAPGDFLDAVVVGMDMMIKKYKETNKGKKRLCLITNAVTPTRNPYEGTKEDQVKTVAAQMMTHGMKMDCVVVRAQKDWDVDKKIVEENDFLLGLLSNKSSSKVYVGNATSLLGALRTRNISPVTTYRGDFELSSIMKIKVWVYKKTCEEKFPTLKKYSDKAPPTDKFA...

XP_057807404.1
MARNKEGLVLVIEVGPSMHGVLPEVEKVCCLLAQKKLIYGKYDEVGVVAFGTTGTKNDLTVEVGGYENVTVLRDIKVVDGDLVDVLHQLPRGGAPGDFLDAVVVGMDMMIKKYKETNKGKKRLCLITNAVTPTRNPYEGTKEDQVKTVAAQMMTHGMKMDCVVVRAQKDWDVDKKIVEENDFLLGLLSNKSSSKVYVGNATSLLGALRTRNISPVTTYRGDFELSSIMKIKVWVYKKTCEEKFPTLKKYSDKAPPTDKFA...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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