Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G000225`

染色体: Chr04 坐标: 2002634-2014761 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G000225`
名称	SmilChr04G000225
描述	DNA replication ATP-dependent helicase/nuclease JHS1
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	2002634 - 2014761 / `+`

ID 对照

NCBI Gene ID	`LOC131022152`
GeneID	`131022152`
locus_tag	`-`
NCBI Name	`LOC131022152`
原始查询	`SmilChr04G000225`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	DNA replication ATP-dependent helicase/nuclease JHS1
产物	DNA replication ATP-dependent helicase/nuclease JHS1
Arabidopsis	`AT1G08840` (emb2411) DNA replication helicase [Source:NCBI gene (formerly Entrezgene);Acc:837406] identity=58.5; qcov=0.874; evalue=0; confidence=high
Rice	`Os04g0588200` - identity=52.4; qcov=0.862; evalue=0; confidence=high
GO	GO:0005737 (cytoplasm); GO:0017108 (5'-flap endonuclease activity); GO:0017116 (single-stranded DNA helicase activity); GO:0071932 (replication fork reversal)
KEGG	smil03030 (DNA replication - Salvia miltiorrhiza (redroot sage))
Pfam	PF00580 (UvrD-helicase); PF08696 (Dna2); PF13086 (AAA_11); PF13087 (AAA_12); PF13245 (AAA_19); PF13604 (AAA_30)
InterPro	-
eggNOG	-
NR	GeneID:131022152

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057807551.1`
2	Nucleolus	核仁	0.20000	`XP_057807551.1`
3	Nucleoplasm	核质	0.20000	`XP_057807551.1`
4	Chromosome	染色体	0.00000	`XP_057807551.1`
5	Centromere	着丝粒	0.00000	`XP_057807551.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:2002768`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B51,C22,C5,C73
`Chr4:2002840`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C21
`Chr4:2002982`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B120
`Chr4:2003072`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B104
`Chr4:2003102`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B59
`Chr4:2003165`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B64
`Chr4:2004307`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C39,C75
`Chr4:2004552`	`GT`	`G`	1bp_deletion	frameshift_variant	1	B59
`Chr4:2004552`	`GT`	`G`	1bp_deletion	CDS_variant	1	B59
`Chr4:2004554`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B59
`Chr4:2005099`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B59
`Chr4:2005209`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B82

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057807551.1

1443 aa

722

1443

Dna2

UvrD-helicase

AAA_11

AAA_30

AAA_19

AAA_11

AAA_12

PF08696 Dna2 460-662 aa PF00580 UvrD-helicase 1024-1089 aa PF13086 AAA_11 1024-1113 aa PF13604 AAA_30 1024-1187 aa PF13245 AAA_19 1028-1187 aa PF13086 AAA_11 1122-1191 aa PF13087 AAA_12 1199-1400 aa

XP_057807552.1

1442 aa

721

1442

Dna2

UvrD-helicase

AAA_11

AAA_30

AAA_19

AAA_11

AAA_12

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057807551.1`	Pfam	`PF08696`	Dna2	Family	460	662	1.3e-61	208.7	DNA replication factor Dna2
`XP_057807551.1`	Pfam	`PF00580`	UvrD-helicase	Domain	1024	1089	1.3e-05	25.7	UvrD/REP helicase N-terminal domain
`XP_057807551.1`	Pfam	`PF13086`	AAA_11	Domain	1024	1113	7.9e-35	121.6	AAA domain
`XP_057807551.1`	Pfam	`PF13604`	AAA_30	Domain	1024	1187	1e-09	39.2	AAA domain
`XP_057807551.1`	Pfam	`PF13245`	AAA_19	Domain	1028	1187	5.9e-08	33.7	AAA domain
`XP_057807551.1`	Pfam	`PF13086`	AAA_11	Domain	1122	1191	7.9e-35	121.6	AAA domain
`XP_057807551.1`	Pfam	`PF13087`	AAA_12	Domain	1199	1400	1.9e-52	178.4	AAA domain
`XP_057807552.1`	Pfam	`PF08696`	Dna2	Family	460	662	1.3e-61	208.7	DNA replication factor Dna2
`XP_057807552.1`	Pfam	`PF00580`	UvrD-helicase	Domain	1024	1089	1.4e-05	25.7	UvrD/REP helicase N-terminal domain
`XP_057807552.1`	Pfam	`PF13086`	AAA_11	Domain	1024	1113	7.9e-35	121.6	AAA domain
`XP_057807552.1`	Pfam	`PF13604`	AAA_30	Domain	1024	1187	1e-09	39.2	AAA domain
`XP_057807552.1`	Pfam	`PF13245`	AAA_19	Domain	1028	1187	5.9e-08	33.7	AAA domain
`XP_057807552.1`	Pfam	`PF13086`	AAA_11	Domain	1122	1191	7.9e-35	121.6	AAA domain
`XP_057807552.1`	Pfam	`PF13087`	AAA_12	Domain	1199	1399	9.7e-53	179.4	AAA domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057951568.1
GTCTCTCACCACTCCCCATTTTCAACCTTCATTCTTTCATCTAATCTTATCGCGCGAAACGAAATCAAACCCCAGTTAATCGTAAATCCGGCTGGCTGGAAACTCCGATTGATGGCTCCGCGGAAGAGGACGAGCTCGGGAGGCAAGAAGTCGAGCAATCCGAATCGCGAGCCGCAGCAATCTGAGCCCTCCAAATTCGGTATACAGCACTTCTTTGAGCGCCACTCCCAGACCCAGAGCCAGAAAACCCTCTCCCAGAA...

XM_057951569.1
GTCTCTCACCACTCCCCATTTTCAACCTTCATTCTTTCATCTAATCTTATCGCGCGAAACGAAATCAAACCCCAGTTAATCGTAAATCCGGCTGGCTGGAAACTCCGATTGATGGCTCCGCGGAAGAGGACGAGCTCGGGAGGCAAGAAGTCGAGCAATCCGAATCGCGAGCCGCAGCAATCTGAGCCCTCCAAATTCGGTATACAGCACTTCTTTGAGCGCCACTCCCAGACCCAGAGCCAGAAAACCCTCTCCCAGAA...

CDS

2 records

下载 CDS FASTA

LOC131022152
ATGGCTCCGCGGAAGAGGACGAGCTCGGGAGGCAAGAAGTCGAGCAATCCGAATCGCGAGCCGCAGCAATCTGAGCCCTCCAAATTCGGTATACAGCACTTCTTTGAGCGCCACTCCCAGACCCAGAGCCAGAAAACCCTCTCCCAGAATAGAGATGACGACCCCACAGGTGGTTCTGCCGCCAATCGAAACTCCCGGATTGTGAATCGTGCTGAAGTGGGGCCGGGGAATCCTGGCGGTGCGGCTAGCTTAGGGAAGAT...

Protein

2 records

下载 Protein FASTA

XP_057807551.1
MAPRKRTSSGGKKSSNPNREPQQSEPSKFGIQHFFERHSQTQSQKTLSQNRDDDPTGGSAANRNSRIVNRAEVGPGNPGGAASLGKIESRTECVRGVNPGSNLVNASDFVSRNDKSGSDVPVDDHIGLCRESSTKSCDDGVVDVNKVEKTENLLKAEVSTRSPDTLRDNLLPVVFDDEENQLEVTPETSKSVSVKRFKFSPGMLIKQSQDDMVDEVTWKISPVNERLHAMSKNLPGRIRVLADSTRFNSMNFQECSQEKV...

XP_057807552.1
MAPRKRTSSGGKKSSNPNREPQQSEPSKFGIQHFFERHSQTQSQKTLSQNRDDDPTGGSAANRNSRIVNRAEVGPGNPGGAASLGKIESRTECVRGVNPGSNLVNASDFVSRNDKSGSDVPVDDHIGLCRESSTKSCDDGVVDVNKVEKTENLLKAEVSTRSPDTLRDNLLPVVFDDEENQLEVTPETSKSVSVKRFKFSPGMLIKQSQDDMVDEVTWKISPVNERLHAMSKNLPGRIRVLADSTRFNSMNFQECSQEKV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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