Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G000228`

染色体: Chr04 坐标: 2028021-2033134 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G000228`
名称	SmilChr04G000228
描述	ribose-phosphate pyrophosphokinase 1
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	2028021 - 2033134 / `-`

ID 对照

NCBI Gene ID	`LOC131022158`
GeneID	`131022158`
locus_tag	`-`
NCBI Name	`LOC131022158`
原始查询	`SmilChr04G000228`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	ribose-phosphate pyrophosphokinase 1
产物	ribose-phosphate pyrophosphokinase 1
Arabidopsis	`AT2G44530` (AT2G44530) Phosphoribosyltransferase family protein [Source:NCBI gene (formerly Entrezgene);Acc:819061] identity=90.7; qcov=0.813; evalue=0; confidence=high
Rice	`Os02g0127700` - identity=79; qcov=0.997; evalue=0; confidence=high
GO	GO:0000287 (magnesium ion binding); GO:0002189 (ribose phosphate diphosphokinase complex); GO:0004749 (ribose phosphate diphosphokinase activity); GO:0005737 (cytoplasm); GO:0006015 (5-phosphoribose 1-diphosphate biosynthetic process); GO:0006164 (purine nucleotide biosynthetic process); GO:0009156 (ribonucleoside monophosphate biosynthetic process)
KEGG	smil00030 (Pentose phosphate pathway - Salvia miltiorrhiza (redroot sage)); smil00230 (Purine metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF00156 (Pribosyltran); PF13793 (Pribosyltran_N); PF14572 (Pribosyl_synth)
InterPro	-
eggNOG	-
NR	GeneID:131022158

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057807561.1`
2	Chloroplast stroma	叶绿体基质	1.00000	`XP_057807561.1`
3	Nucleus	细胞核	0.00000	`XP_057807561.1`
4	Chromosome	染色体	0.00000	`XP_057807561.1`
5	Centromere	着丝粒	0.00000	`XP_057807561.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:2028336`	`A`	`AG`	1bp_insertion	frameshift_variant	3	B104,B38,B39
`Chr4:2028336`	`A`	`AG`	1bp_insertion	CDS_variant	3	B104,B38,B39
`Chr4:2028337`	`C`	`CT`	1bp_insertion	frameshift_variant	123	A1,A11,A13,A18,A21,A22,A23,A5,A7,A9,B10,B100,B101,B103,B111,B112,B115,B117,B120,B121,B122,B124,B129,B13,B130,B132,B137,B140,B15,B17,B18,B24,B28,B29,B30,B35,B36,B37,B42,B43,B44,B45,B47,B48,B50,B52,B53,B54,B57,B58,B59,B6,B62,B64,B65,B70,B71,B75,B76,B78,B79,B8,B88,B9,B94,B95,B98,B99,C1,C12,C13,C14,C16,C18,C19,C2,C23,C25,C26,C28,C30,C32,C35,C36,C37,C39,C42,C45,C46,C48,C50,C51,C52,C54,C55,C56,C58,C59,C61,C62,C64,C65,C66,C67,C68,C70,C71,C72,C73,C75,C76,C78,C80,C82,C83,C84,C9,D11,D2,D3,D4,D6,D7
`Chr4:2028348`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B104,B38,B39
`Chr4:2028364`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C65
`Chr4:2028517`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C15
`Chr4:2028960`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr4:2030614`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	C28,C76,C9,D2
`Chr4:2031069`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B13
`Chr4:2031111`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B104,B64
`Chr4:2032612`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr4:2032640`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B139,B45,B49,B79,C6

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057807561.1

404 aa

202

404

Pribosyltran_N

Pribosyltran

Pribosyl_synth

PF13793 Pribosyltran_N 81-196 aa PF00156 Pribosyltran 240-327 aa PF14572 Pribosyl_synth 281-388 aa

XP_057807562.1

396 aa

198

396

Pribosyltran_N

Pribosyltran

Pribosyl_synth

PF13793 Pribosyltran_N 81-196 aa PF00156 Pribosyltran 240-327 aa PF14572 Pribosyl_synth 281-382 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057807561.1`	Pfam	`PF13793`	Pribosyltran_N	Domain	81	196	6.6e-53	178.2	N-terminal domain of ribose phosphate pyrophosphokinase
`XP_057807561.1`	Pfam	`PF00156`	Pribosyltran	Domain	240	327	1.8e-16	60.6	Phosphoribosyl transferase domain
`XP_057807561.1`	Pfam	`PF14572`	Pribosyl_synth	Domain	281	388	4.3e-24	86.2	Phosphoribosyl synthetase-associated domain
`XP_057807562.1`	Pfam	`PF13793`	Pribosyltran_N	Domain	81	196	6.4e-53	178.3	N-terminal domain of ribose phosphate pyrophosphokinase
`XP_057807562.1`	Pfam	`PF00156`	Pribosyltran	Domain	240	327	1.6e-16	60.7	Phosphoribosyl transferase domain
`XP_057807562.1`	Pfam	`PF14572`	Pribosyl_synth	Domain	281	382	2.7e-23	83.6	Phosphoribosyl synthetase-associated domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057951579.1
AAAACAAACAAGGGGTTTAATTTAAGTTGTAAAAAAGCGAGCCAAAAAAGACTAGCTCGGTAGATATTTTTCTCGAAGGAAATCGTTAAAACCCTAACTCCTAAATATCGCTCGCCACAAACCGGAAAAGGAAGTCTCGCCTGATTTTCGTCGGAGAAGATGGCTTCTATGGCCTTATCCGGAGGCGGCCTACTGAAATCGCCTCAACTCACTTCTAAAACCTCATTTCTCATTCGGTGTAACAATTTGTCGGAGTCACT...

XM_057951578.1
ACAAACAAGGGGTTTAATTTAAGTTGTAAAAAAGCGAGCCAAAAAAGACTAGCTCGGTAGATATTTTTCTCGAAGGAAATCGTTAAAACCCTAACTCCTAAATATCGCTCGCCACAAACCGGAAAAGGAAGTCTCGCCTGATTTTCGTCGGAGAAGATGGCTTCTATGGCCTTATCCGGAGGCGGCCTACTGAAATCGCCTCAACTCACTTCTAAAACCTCATTTCTCATTCGGTGTAACAATTTGTCGGAGTCACTGAA...

CDS

2 records

下载 CDS FASTA

LOC131022158
ATGGCTTCTATGGCCTTATCCGGAGGCGGCCTACTGAAATCGCCTCAACTCACTTCTAAAACCTCATTTCTCATTCGGTGTAACAATTTGTCGGAGTCACTGAAGTGCAAGGACAATGGAAGACCGGTGACCGTTAGCCGGGATTCTAACGGTCGGGCGGCGGTGGCGCTGCCCAGCTTCTTGACCACCCCCAATCAGTTCTTGGACAGAATCCCGGTTCCGAAAAACGACACGCGTCTCCGCATTTTCTCCGGCACTGC...

Protein

2 records

下载 Protein FASTA

XP_057807561.1
MASMALSGGGLLKSPQLTSKTSFLIRCNNLSESLKCKDNGRPVTVSRDSNGRAAVALPSFLTTPNQFLDRIPVPKNDTRLRIFSGTANPSLSQEIACYMGLELGKIKIKRFADGEIYVQLQESVRGCDVYLVQPTCPPANENLMELLIMIDACRRASAKNITAVIPYFGYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVHGQPVILDYLASKTICSDDLVVVSPDVGGVARARAFAKK...

XP_057807562.1
MASMALSGGGLLKSPQLTSKTSFLIRCNNLSESLKCKDNGRPVTVSRDSNGRAAVALPSFLTTPNQFLDRIPVPKNDTRLRIFSGTANPSLSQEIACYMGLELGKIKIKRFADGEIYVQLQESVRGCDVYLVQPTCPPANENLMELLIMIDACRRASAKNITAVIPYFGYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVHGQPVILDYLASKTICSDDLVVVSPDVGGVARARAFAKK...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器