Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G000563`

染色体: Chr04 坐标: 6278320-6285597 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G000563`
名称	SmilChr04G000563
描述	uncharacterized SmilChr04G000563
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	6278320 - 6285597 / `-`

ID 对照

NCBI Gene ID	`LOC131022446`
GeneID	`131022446`
locus_tag	`-`
NCBI Name	`LOC131022446`
原始查询	`SmilChr04G000563`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	2-oxoglutarate dehydrogenase, E1 component [Source:NCBI gene (formerly Entrezgene);Acc:836704]; symbol=AT5G65750; hit=AT5G65750; species=arabidopsis; confidence=high
产物	2-oxoglutarate dehydrogenase, E1 component [Source:NCBI gene (formerly Entrezgene);Acc:836704]; symbol=AT5G65750; hit=AT5G65750; species=arabidopsis; confidence=high
Arabidopsis	`AT5G65750` (AT5G65750) 2-oxoglutarate dehydrogenase, E1 component [Source:NCBI gene (formerly Entrezgene);Acc:836704] identity=85.5; qcov=1; evalue=0; confidence=high
Rice	`Os04g0390000` - identity=83.7; qcov=1; evalue=0; confidence=high
GO	GO:0004591 (oxoglutarate dehydrogenase (succinyl-transferring) activity); GO:0005739 (mitochondrion); GO:0006099 (tricarboxylic acid cycle); GO:0030976 (thiamine pyrophosphate binding); GO:0045252 (oxoglutarate dehydrogenase complex)
KEGG	smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil00785 (Lipoic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00676 (E1_dh); PF02779 (Transket_pyr); PF16078 (2-oxogl_dehyd_N); PF16870 (OxoGdeHyase_C)
InterPro	-
eggNOG	-
NR	GeneID:131022446

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057807915.1`
2	Mitochondrion matrix	线粒体基质	1.00000	`XP_057807915.1`
3	Nucleus	细胞核	0.00000	`XP_057807915.1`
4	Chromosome	染色体	0.00000	`XP_057807915.1`
5	Centromere	着丝粒	0.00000	`XP_057807915.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:6278860`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B25,D2
`Chr4:6278870`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A25,B91,C35,C50
`Chr4:6278883`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C15
`Chr4:6278973`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr4:6279120`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B20
`Chr4:6279645`	`GC`	`G`	1bp_deletion	frameshift_variant	1	C79
`Chr4:6279645`	`GC`	`G`	1bp_deletion	CDS_variant	1	C79
`Chr4:6279753`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B121,B81
`Chr4:6281169`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C60
`Chr4:6282731`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B13
`Chr4:6282761`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A25,B91,C35,C50
`Chr4:6282869`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C7

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057807915.1

1018 aa

509

1018

2-oxogl_dehyd_N

E1_dh

Transket_pyr

OxoGdeHyase_C

PF16078 2-oxogl_dehyd_N 64-101 aa PF00676 E1_dh 245-565 aa PF02779 Transket_pyr 635-848 aa PF16870 OxoGdeHyase_C 871-1011 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057807915.1`	Pfam	`PF16078`	2-oxogl_dehyd_N	Family	64	101	7e-16	58.2	2-oxoglutarate dehydrogenase N-terminus
`XP_057807915.1`	Pfam	`PF00676`	E1_dh	Domain	245	565	1.1e-60	205.9	Dehydrogenase E1 component
`XP_057807915.1`	Pfam	`PF02779`	Transket_pyr	Domain	635	848	4.7e-49	167.1	Transketolase, pyrimidine binding domain
`XP_057807915.1`	Pfam	`PF16870`	OxoGdeHyase_C	Family	871	1011	4.4e-51	173.3	2-oxoglutarate dehydrogenase C-terminal

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057951932.1
AAAGAAATGCACCGAAAATGGGGAACAAATGCTATAAAATGGAGCTTGGATTGGGAAAAATGTGCAGATACAGCCTAAGAAAGAGCTAATCGCAGCAGATTAGGGTTTAGTCTTCGCTTGGAGCATGGTTCTCTCTTTTTCTCAGGATGTTTTGGAGATAGAATGACAGTGCATAGCGCTTGATTTGGTTGGAATAGCATCAAACTTTCGCAGTCGTGGTCGTTGTAAACTAGATTTTGTAATAGCTATGGCGTGGCTTA...

CDS

1 records

下载 CDS FASTA

LOC131022446
ATGGCGTGGCTTAGAGTTGGCTCTAATGTGGCAAAGCTCGCTGTTAGACGGACTTTATCTCAAACTGGTTCCTATGTAGCTCGGCCAGGGGTTGCTCCTGAACGGAGTCGATATTTCCATGCTACAGTTTTTAGATCAAAGGCTCAATCTGCGCCTGCTCCTCGGCCTGTTCCTCTCTCCAGGTTGAGTGATAGCTTTCTAGATGGCACGAGTAGTGTTTATCTTGAGGAGCTACAGAGAGCCTGGGAGCAAGATCCCAA...

Protein

1 records

下载 Protein FASTA

XP_057807915.1
MAWLRVGSNVAKLAVRRTLSQTGSYVARPGVAPERSRYFHATVFRSKAQSAPAPRPVPLSRLSDSFLDGTSSVYLEELQRAWEQDPNSVDESWDNFFRNFVGQATTSPGISGQTIQESMRLLLLVRAYQVYGHMKAKIDPLGLEQRSIPDDLDPALYGFSEADLDREFFIGVWRMAGFLSENRPVQTLRAILKRLEQAYCGSIGYEYMHIADREKCNWLRDKIETPTLTQYNRQRREVILDRLIWSTQFENFLAAKWTAA...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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