Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G000667`

染色体: Chr04 坐标: 7541721-7543974 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G000667`
名称	SmilChr04G000667
描述	NADPH-dependent aldo-keto reductase, chloroplastic-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	7541721 - 7543974 / `-`

ID 对照

NCBI Gene ID	`LOC131022540`
GeneID	`131022540`
locus_tag	`-`
NCBI Name	`LOC131022540`
原始查询	`SmilChr04G000667`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	NADPH-dependent aldo-keto reductase, chloroplastic-like
产物	NADPH-dependent aldo-keto reductase%2C chloroplastic-like
Arabidopsis	`AT2G37770` (ChlAKR) NAD(P)-linked oxidoreductase superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:818354] identity=72.1; qcov=1.01; evalue=5.04e-173; confidence=high
Rice	`Os01g0847700` (AKR2) - identity=67.6; qcov=1.01; evalue=2.3e-156; confidence=high
GO	GO:0004032 (aldose reductase (NADPH) activity); GO:0005829 (cytosol)
KEGG	smil00010 (Glycolysis / Gluconeogenesis - Salvia miltiorrhiza (redroot sage)); smil00040 (Pentose and glucuronate interconversions - Salvia miltiorrhiza (redroot sage)); smil00053 (Ascorbate and aldarate metabolism - Salvia miltiorrhiza (redroot sage)); smil00561 (Glycerolipid metabolism - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01240 (Biosynthesis of cofactors - Salvia miltiorrhiza (redroot sage))
Pfam	PF00248 (Aldo_ket_red)
InterPro	-
eggNOG	-
NR	GeneID:131022540

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057808031.1`
2	Cytoplasm	细胞质	0.80000	`XP_057808031.1`
3	Chloroplast	叶绿体	0.20000	`XP_057808031.1`
4	Nucleus	细胞核	0.00000	`XP_057808031.1`
5	Chromosome	染色体	0.00000	`XP_057808031.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:7542306`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D4
`Chr4:7542364`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B119,B33,B44,C20
`Chr4:7542402`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B59,D7
`Chr4:7542572`	`CT`	`C`	1bp_deletion	frameshift_variant	5	A20,B50,B63,C19,C54
`Chr4:7542572`	`CT`	`C`	1bp_deletion	CDS_variant	5	A20,B50,B63,C19,C54
`Chr4:7542574`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr4:7542635`	`G`	`A`	EMS_canonical_SNV	stop_gained	1	D4
`Chr4:7542635`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D4
`Chr4:7543166`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A20,B50,B63,C19,C54
`Chr4:7543784`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A3,B137,B25,B69,C41
`Chr4:7543788`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B131,B75
`Chr4:7543795`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C84

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057808031.1

313 aa

156

313

Aldo_ket_red

PF00248 Aldo_ket_red 20-283 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057808031.1`	Pfam	`PF00248`	Aldo_ket_red	Domain	20	283	2.5e-48	165.4	Aldo/keto reductase family

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057952048.1
TGGAAATGGAGGAATAGGATTCCAAATGCACAAATAGTAGCAAACAAGACGGCCTAAAATCTGCAACTAAATATTTATTTATAAATCCCAATGGCGAAACAGATTCGACTTTTCCGGCTGAATAACGGCGCCAAAATCCCATCGGTCGGGCTCGGCACGTGGAAGGCCGATCACGGCGTCGTCGGCGACGCCATCACCGCCGCAATTAAGGCAGGATATCGGCATATTGATTGTGCTCAAAGATATGGCAATGAGAAAGA...

CDS

1 records

下载 CDS FASTA

LOC131022540
ATGGCGAAACAGATTCGACTTTTCCGGCTGAATAACGGCGCCAAAATCCCATCGGTCGGGCTCGGCACGTGGAAGGCCGATCACGGCGTCGTCGGCGACGCCATCACCGCCGCAATTAAGGCAGGATATCGGCATATTGATTGTGCTCAAAGATATGGCAATGAGAAAGAGATTGGTAACACCCTCAAGAAGCTGTTTGAAGAAGGAGTAGTGAAGCGCGACGAACTATGGATTACTTCTAAACTCTGGTGTTCTGATCA...

Protein

1 records

下载 Protein FASTA

XP_057808031.1
MAKQIRLFRLNNGAKIPSVGLGTWKADHGVVGDAITAAIKAGYRHIDCAQRYGNEKEIGNTLKKLFEEGVVKRDELWITSKLWCSDHAPEDVPLALNRTLGDLQLDYVDLYLMHWPVSMKKGSVAFEPENLTSVDIPSTWMAMESLCDAGKARAIGVSNFSSKKLGDLLGIARIPPAVNQVECHPGWQQQQLHSFCESKGVHLSGYSPLGSSSNHGSNMLKNPVLNLVGERLGKTPAQVALRWGLQMGHSVLPKSTNEKR...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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