Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G000901`

染色体: Chr04 坐标: 11735468-11741559 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G000901`
名称	SmilChr04G000901
描述	aldose reductase
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	11735468 - 11741559 / `+`

ID 对照

NCBI Gene ID	`LOC131022727`
GeneID	`131022727`
locus_tag	`-`
NCBI Name	`LOC131022727`
原始查询	`SmilChr04G000901`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	aldose reductase
产物	aldose reductase
Arabidopsis	`AT5G01670` (AT5G01670) NAD(P)-linked oxidoreductase superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:831701] identity=67.4; qcov=0.928; evalue=5.1e-173; confidence=high
Rice	`Os05g0474600` - identity=64.3; qcov=0.928; evalue=2.33e-158; confidence=high
GO	GO:0004032 (aldose reductase (NADPH) activity); GO:0005829 (cytosol)
KEGG	smil00010 (Glycolysis / Gluconeogenesis - Salvia miltiorrhiza (redroot sage)); smil00040 (Pentose and glucuronate interconversions - Salvia miltiorrhiza (redroot sage)); smil00053 (Ascorbate and aldarate metabolism - Salvia miltiorrhiza (redroot sage)); smil00561 (Glycerolipid metabolism - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01240 (Biosynthesis of cofactors - Salvia miltiorrhiza (redroot sage))
Pfam	PF00248 (Aldo_ket_red)
InterPro	-
eggNOG	-
NR	GeneID:131022727

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057808224.1`
2	Cytosol	细胞质基质	0.60000	`XP_057808224.1`
3	Nucleus	细胞核	0.40000	`XP_057808224.1`
4	Chromosome	染色体	0.00000	`XP_057808224.1`
5	Centromere	着丝粒	0.00000	`XP_057808224.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:11735481`	`A`	`ATT`	2bp_insertion	frameshift_variant	61	A3,A4,A9,B10,B100,B101,B102,B108,B115,B120,B122,B124,B125,B13,B130,B139,B140,B15,B16,B17,B19,B22,B27,B30,B31,B40,B42,B43,B52,B57,B62,B64,B78,B80,B82,B88,C11,C17,C19,C27,C3,C30,C31,C35,C36,C41,C43,C45,C46,C49,C52,C53,C55,C59,C69,C74,C85,D11,D3,D4,D7
`Chr4:11735500`	`GT`	`G`	1bp_deletion	frameshift_variant	2	B66,C79
`Chr4:11735500`	`GT`	`G`	1bp_deletion	CDS_variant	2	B66,C79
`Chr4:11737726`	`GT`	`G`	1bp_deletion	frameshift_variant	1	B5
`Chr4:11737726`	`GT`	`G`	1bp_deletion	CDS_variant	1	B5
`Chr4:11737840`	`TG`	`T`	1bp_deletion	frameshift_variant	49	A11,A18,A23,A24,B103,B106,B107,B121,B126,B128,B132,B133,B134,B138,B140,B17,B23,B29,B3,B37,B4,B40,B55,B62,B68,B69,B70,B71,B75,B94,C12,C16,C17,C21,C24,C25,C27,C30,C32,C36,C45,C48,C51,C56,C61,C68,C77,C86,D1
`Chr4:11739318`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B78
`Chr4:11739322`	`C`	`T`	EMS_canonical_SNV	stop_gained	1	D10
`Chr4:11739322`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr4:11739396`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B41
`Chr4:11739426`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A16,B83,C59
`Chr4:11740430`	`G`	`A`	EMS_canonical_SNV	stop_gained	1	C84

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057808224.1

347 aa

174

347

Aldo_ket_red

PF00248 Aldo_ket_red 52-315 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057808224.1`	Pfam	`PF00248`	Aldo_ket_red	Domain	52	315	5.4e-47	161.0	Aldo/keto reductase family

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057952241.1
TCGAAATGAACCCATTTATAAGAAGCCAGAAAGTTGAAGAATATCAAACTACAGCTGTCCTAAAATACAGGGAATCATCAATGGCGCAAGCTAGTTTTGCTCCGCAGAGTGAGAAGATGGAAACATTTAGGTTGATGAGTGGGTTTCTGATCCCTGCTGTCGGAATCGGCACTTGGAAATTATCTCCATCTCCTCGACAATCTCTTCAAACTGCTCTTATTGAGGCAGGTTATAGGCATGTTGACACGGCGGCCCAATAT...

CDS

1 records

下载 CDS FASTA

LOC131022727
ATGAACCCATTTATAAGAAGCCAGAAAGTTGAAGAATATCAAACTACAGCTGTCCTAAAATACAGGGAATCATCAATGGCGCAAGCTAGTTTTGCTCCGCAGAGTGAGAAGATGGAAACATTTAGGTTGATGAGTGGGTTTCTGATCCCTGCTGTCGGAATCGGCACTTGGAAATTATCTCCATCTCCTCGACAATCTCTTCAAACTGCTCTTATTGAGGCAGGTTATAGGCATGTTGACACGGCGGCCCAATATGGAAA...

Protein

1 records

下载 Protein FASTA

XP_057808224.1
MNPFIRSQKVEEYQTTAVLKYRESSMAQASFAPQSEKMETFRLMSGFLIPAVGIGTWKLSPSPRQSLQTALIEAGYRHVDTAAQYGNQIEVGKGIKTAIHAGIERKHLFITSKIWCTDLVPERVGPAFLRTLEELQLEYLDLYLIHWPFRLRDGATRPPRGDDVLEFDMEGVWREMEKLVVEGFVRDIGICNFTLKKLDKLLSFARIKPSVCQMEMHPGWRNDKMLEACKKNDIHVTSYSPLGSQEGGRDLVHDPVVDRV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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