Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G001513`

染色体: Chr04 坐标: 24938199-24946809 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G001513`
名称	SmilChr04G001513
描述	delta-1-pyrroline-5-carboxylate synthase
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	24938199 - 24946809 / `+`

ID 对照

NCBI Gene ID	`LOC131019536`
GeneID	`131019536`
locus_tag	`-`
NCBI Name	`LOC131019536`
原始查询	`SmilChr04G001513`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	delta-1-pyrroline-5-carboxylate synthase
产物	delta-1-pyrroline-5-carboxylate synthase
Arabidopsis	`AT3G55610` (P5CS2) delta 1-pyrroline-5-carboxylate synthase 2 [Source:NCBI gene (formerly Entrezgene);Acc:824727] identity=75.5; qcov=0.959; evalue=0; confidence=high
Rice	`Os05g0455500` (OsP5CS) delta-1-pyrroline-5-carboxylate synthase 1-like [Source:NCBI gene (formerly Entrezgene);Acc:4338979] identity=76; qcov=0.942; evalue=0; confidence=high
GO	GO:0004349 (glutamate 5-kinase activity); GO:0004350 (glutamate-5-semialdehyde dehydrogenase activity); GO:0005524 (ATP binding); GO:0005737 (cytoplasm); GO:0006561 (GO:0006561)
KEGG	smil00330 (Arginine and proline metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF00171 (Aldedh); PF00696 (AA_kinase)
InterPro	-
eggNOG	-
NR	GeneID:131019536

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057804082.1`
2	Cytoplasm	细胞质	0.80000	`XP_057804082.1`
3	Nucleus	细胞核	0.00000	`XP_057804082.1`
4	Chromosome	染色体	0.00000	`XP_057804082.1`
5	Centromere	着丝粒	0.00000	`XP_057804082.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:24941102`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B105,B18,B31,C49
`Chr4:24944325`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B122,B2,C11,C69
`Chr4:24945522`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A25,B91,C57
`Chr4:24946508`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B82,B99,C48,D7
`Chr4:24946510`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B98
`Chr4:24946520`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C30
`Chr4:24946524`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B122,B2,C11,C69
`Chr4:24946581`	`TGA`	`T`	2bp_deletion	frameshift_variant	12	B106,B129,B21,B36,B73,B89,B90,B92,C26,C31,C80,C86
`Chr4:24946664`	`CTG`	`C`	2bp_deletion	frameshift_variant	5	B105,B117,B18,B31,C49
`Chr4:24946664`	`CTG`	`C`	2bp_deletion	CDS_variant	5	B105,B117,B18,B31,C49
`Chr4:24946688`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B82,B99,C48,D7

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057804082.1

760 aa

380

760

AA_kinase

Aldedh

PF00696 AA_kinase 15-260 aa PF00171 Aldedh 295-557 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057804082.1`	Pfam	`PF00696`	AA_kinase	Family	15	260	5.6e-40	138.2	Amino acid kinase family
`XP_057804082.1`	Pfam	`PF00171`	Aldedh	Family	295	557	6e-12	45.6	Aldehyde dehydrogenase family

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057948099.1
CCCGCACGACAGAATGATAAACCTACGCGGAGCTTTTGCATTGCTCCTCAGAAGAAGACAAAAAAGTGGCGCAGAAAAGCCCTCGCTCGCATTTCTCCTCTGGCTGCTGTCACTCTTCACCCGTATCTATATTTATATGTATGCGCCATGTGCCCAAAACCCTATAAATACAAAGCTCTGCTCACGGGTCTCCTTCTCCATCCACGCTTCAATCTAATTCTGCATTCCATACTACCTCACTTTCTCTCTCTAAAACCTTC...

CDS

1 records

下载 CDS FASTA

LOC131019536
ATGGACGCTGCTGATTCCACTCGCTCATTTTTGAGAGACGTCAAACGCATCGTCATCAAAGTGGGAACAGCCGTAGTAACTCAAGCTGATGGGCGTCTAGCTCTTGGAAGATTAGGCTCACTTTGTGAGCAGATCCATGAACTGAATACTGAGGGCTACGAGGTGATTTTGGTGACTTCAGGTGCAGTTGGTGTTGGCCGCCAACGGCTTCGATACAGGAGATTAGTTAACAGCAGCTTTGCAGACCTTCAAAAGCCGCA...

Protein

1 records

下载 Protein FASTA

XP_057804082.1
MDAADSTRSFLRDVKRIVIKVGTAVVTQADGRLALGRLGSLCEQIHELNTEGYEVILVTSGAVGVGRQRLRYRRLVNSSFADLQKPQVELDGKACAAVGQNGLMALYDTLFSQLDVTSAQLLVTDNDFRDPDFRRQLNETVKSLLSLKVVPIFNENDAISTRKAPYEDASGIFWDNDSLAALLALELKADLLVLLSDVDGLYSGPPSDPHSELIHTYAKERHDGLITFGDKSRVGRGGMTAKVKAAVYAAYAGIPVVITS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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