Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G001517`

染色体: Chr04 坐标: 25025588-25029764 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G001517`
名称	SmilChr04G001517
描述	mannose-1-phosphate guanylyltransferase 1
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	25025588 - 25029764 / `-`

ID 对照

NCBI Gene ID	`LOC131019539`
GeneID	`131019539`
locus_tag	`-`
NCBI Name	`LOC131019539`
原始查询	`SmilChr04G001517`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	mannose-1-phosphate guanylyltransferase 1
产物	mannose-1-phosphate guanylyltransferase 1
Arabidopsis	`AT2G39770` (CYT1) Glucose-1-phosphate adenylyltransferase family protein [Source:NCBI gene (formerly Entrezgene);Acc:818562] identity=91.1; qcov=1; evalue=0; confidence=high
Rice	`Os03g0268400` (OsMPG3) - identity=88.4; qcov=1; evalue=0; confidence=high
GO	GO:0000032 (cell wall mannoprotein biosynthetic process); GO:0004475 (mannose-1-phosphate guanylyltransferase (GTP) activity); GO:0005525 (GTP binding); GO:0005737 (cytoplasm); GO:0006486 (GO:0006486); GO:0009298 (GDP-mannose biosynthetic process)
KEGG	smil00051 (Fructose and mannose metabolism - Salvia miltiorrhiza (redroot sage)); smil00520 (Amino sugar and nucleotide sugar metabolism - Salvia miltiorrhiza (redroot sage)); smil00541 (Biosynthesis of various nucleotide sugars - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01240 (Biosynthesis of cofactors - Salvia miltiorrhiza (redroot sage)); smil01250 (Biosynthesis of nucleotide sugars - Salvia miltiorrhiza (redroot sage))
Pfam	PF00132 (Hexapep); PF00483 (NTP_transferase); PF12804 (NTP_transf_3); PF25087 (GMPPB_C)
InterPro	-
eggNOG	-
NR	GeneID:131019539

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057804086.1`
2	Cytosol	细胞质基质	0.80000	`XP_057804086.1`
3	Nucleus	细胞核	0.40000	`XP_057804086.1`
4	Chromosome	染色体	0.00000	`XP_057804086.1`
5	Centromere	着丝粒	0.00000	`XP_057804086.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:25025787`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C38
`Chr4:25025934`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	B139,C18,C22,C44
`Chr4:25025955`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B37
`Chr4:25025956`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	C37
`Chr4:25026032`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B52
`Chr4:25026269`	`C`	`CAA`	2bp_insertion	frameshift_variant	3	B105,C9,D2
`Chr4:25026269`	`C`	`CAA`	2bp_insertion	CDS_variant	3	B105,C9,D2
`Chr4:25026373`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B138,C70
`Chr4:25026548`	`CG`	`C`	1bp_deletion	frameshift_variant	48	A24,A4,A9,B102,B104,B112,B115,B135,B138,B20,B21,B23,B27,B30,B32,B33,B40,B45,B47,B54,B59,B61,B63,B66,B76,B77,B8,B80,B86,B88,B89,B90,B92,B98,C16,C24,C3,C32,C34,C36,C40,C43,C53,C66,C68,C70,C84,C86
`Chr4:25026550`	`ATC`	`A`	2bp_deletion	frameshift_variant	47	A24,A4,A9,B102,B104,B112,B115,B135,B138,B20,B21,B23,B27,B30,B32,B33,B40,B45,B47,B54,B59,B63,B66,B76,B77,B8,B80,B86,B88,B89,B90,B92,B98,C16,C24,C3,C32,C34,C36,C40,C43,C53,C66,C68,C70,C84,C86
`Chr4:25026574`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B20,B61,B8
`Chr4:25026597`	`GA`	`G`	1bp_deletion	frameshift_variant	61	A13,A14,A23,A24,A4,A9,B102,B115,B118,B133,B135,B138,B20,B21,B23,B27,B30,B32,B33,B4,B40,B45,B47,B54,B59,B61,B63,B67,B68,B72,B74,B76,B77,B8,B80,B86,B88,B89,B92,B98,C16,C17,C2,C24,C29,C3,C32,C36,C40,C43,C48,C57,C59,C61,C66,C68,C70,C83,C86,D10,D3

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057804086.1

361 aa

180

361

NTP_transferase

NTP_transf_3

GMPPB_C

Hexapep

PF00483 NTP_transferase 2-233 aa PF12804 NTP_transf_3 3-138 aa PF25087 GMPPB_C 251-360 aa PF00132 Hexapep 261-294 aa

XP_057804087.1

361 aa

180

361

NTP_transferase

NTP_transf_3

GMPPB_C

Hexapep

PF00483 NTP_transferase 2-233 aa PF12804 NTP_transf_3 3-138 aa PF25087 GMPPB_C 251-360 aa PF00132 Hexapep 261-294 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057804086.1`	Pfam	`PF00483`	NTP_transferase	Family	2	233	3.3e-60	204.4	Nucleotidyl transferase
`XP_057804086.1`	Pfam	`PF12804`	NTP_transf_3	Domain	3	138	5e-09	37.3	MobA-like NTP transferase domain
`XP_057804086.1`	Pfam	`PF25087`	GMPPB_C	Repeat	251	360	3.9e-44	149.6	GMPPB C-terminal domain
`XP_057804086.1`	Pfam	`PF00132`	Hexapep	Repeat	261	294	4e-09	36.5	Bacterial transferase hexapeptide (six repeats)
`XP_057804087.1`	Pfam	`PF00483`	NTP_transferase	Family	2	233	3.3e-60	204.4	Nucleotidyl transferase
`XP_057804087.1`	Pfam	`PF12804`	NTP_transf_3	Domain	3	138	5e-09	37.3	MobA-like NTP transferase domain
`XP_057804087.1`	Pfam	`PF25087`	GMPPB_C	Repeat	251	360	3.9e-44	149.6	GMPPB C-terminal domain
`XP_057804087.1`	Pfam	`PF00132`	Hexapep	Repeat	261	294	4e-09	36.5	Bacterial transferase hexapeptide (six repeats)

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057948104.1
GTGGATTTATTCAATTATTGAAATTTGTAAATTATTAGGACGACAAAGTGGATTAAAAAATTTGTGAATAAATGTTACGTATTGAATCGATAAAAGGAAGTCATAAGTTCGTTATATATACATACAAAAGCAAGTGTATATATTTATCCTTCCCAAGCATTCTTGTTTGTCCCACATTCTCTCTTCATCTCTCAGGAAAACCACAAATCGTTGGGGTTTGTGGTAAACTGAGGATTATACCACATTTGTTGACTCGGTCT...

XM_057948103.1
ACATACAAAAGCAAGTGTATATATTTATCCTTCCCAAGCATTCTTGTTTGTCCCACATTCTCTCTTCATCTCTCAGGAAAACCACAAATCGTTGGGGTTTGTGGTAAACTGAGGATTATACCACATTTGTTGACTCGGTCTTGGATTCGACTTGCTTCTTTGACTCGGCCTAGATCTGCTGTAAACCCCAAAAGAAGAAGTGCAAGACAGTTATGGAAGGCCGACAACATTGATTAGGCCATGATGCTTATCATCATGTT...

CDS

2 records

下载 CDS FASTA

LOC131019539
ATGAAGGCACTAATTCTTGTTGGAGGGTTTGGCACTAGATTGAGACCATTGACGCTGAGTGTGCCTAAGCCGCTCGTTGATTTTGCTAACAAGCCTATGATTTTGCACCAGATAGAAGCCCTCAAGGCTATTGGAGTAACTGAAGTAGTCCTAGCCATCAATTATCAGCCAGAGGTAATGCTGAACTTTTTGAAAGATTTTGAGGCAAAGCTTGAGATTAAGATCACATGTTCGCAAGAGACTGAACCTCTTGGAACAGC...

Protein

2 records

下载 Protein FASTA

XP_057804086.1
MKALILVGGFGTRLRPLTLSVPKPLVDFANKPMILHQIEALKAIGVTEVVLAINYQPEVMLNFLKDFEAKLEIKITCSQETEPLGTAGPLALARDKLIDKSGEPFFVLNSDVISEYPLKEMIEFHKSHGGEASIMVTKVDEPSKYGVVVTEESTGKVERFVEKPKLFVGNKINAGIYLLNPSVLDRIQLRPTSIEKEVFPEIAAERKLYAMVLPGFWMDIGQPRDYIAGLRLYLDSLRKNSSPKLASGTHIIGNVLVDES...

XP_057804087.1
MKALILVGGFGTRLRPLTLSVPKPLVDFANKPMILHQIEALKAIGVTEVVLAINYQPEVMLNFLKDFEAKLEIKITCSQETEPLGTAGPLALARDKLIDKSGEPFFVLNSDVISEYPLKEMIEFHKSHGGEASIMVTKVDEPSKYGVVVTEESTGKVERFVEKPKLFVGNKINAGIYLLNPSVLDRIQLRPTSIEKEVFPEIAAERKLYAMVLPGFWMDIGQPRDYIAGLRLYLDSLRKNSSPKLASGTHIIGNVLVDES...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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