Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G002019`

染色体: Chr04 坐标: 32761675-32764681 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G002019`
名称	SmilChr04G002019
描述	pyruvate decarboxylase 1-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	32761675 - 32764681 / `-`

ID 对照

NCBI Gene ID	`LOC131021189`
GeneID	`131021189`
locus_tag	`-`
NCBI Name	`LOC131021189`
原始查询	`SmilChr04G002019`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	pyruvate decarboxylase 1-like
产物	pyruvate decarboxylase 1-like
Arabidopsis	`AT5G01320` (AT5G01320) Thiamine pyrophosphate dependent pyruvate decarboxylase family protein [Source:NCBI gene (formerly Entrezgene);Acc:830867] identity=79.1; qcov=1.03; evalue=0; confidence=high
Rice	`Os03g0293500` (pdc2*) - identity=82.9; qcov=0.983; evalue=0; confidence=high
GO	GO:0000287 (magnesium ion binding); GO:0016831 (carboxy-lyase activity); GO:0030976 (thiamine pyrophosphate binding)
KEGG	smil00010 (Glycolysis / Gluconeogenesis - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage))
Pfam	PF00205 (TPP_enzyme_M); PF02775 (TPP_enzyme_C); PF02776 (TPP_enzyme_N)
InterPro	-
eggNOG	-
NR	GeneID:131021189

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytosol	细胞质基质	1.00000	`XP_057806268.1`
2	Cytoplasm	细胞质	0.80000	`XP_057806268.1`
3	Nucleus	细胞核	0.00000	`XP_057806268.1`
4	Chromosome	染色体	0.00000	`XP_057806268.1`
5	Centromere	着丝粒	0.00000	`XP_057806268.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:32761837`	`GC`	`G`	1bp_deletion	frameshift_variant	1	B100
`Chr4:32761837`	`GC`	`G`	1bp_deletion	CDS_variant	1	B100
`Chr4:32761942`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C8
`Chr4:32762064`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B140,C33
`Chr4:32762073`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B104,B140,B44,B54,C33
`Chr4:32762129`	`G`	`A`	EMS_canonical_SNV	stop_gained	7	B115,B21,B3,B35,B90,C33,C62
`Chr4:32762130`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B54
`Chr4:32762160`	`AC`	`A`	1bp_deletion	frameshift_variant	114	A10,A14,A16,A2,A20,A23,A24,A4,A5,A6,A8,B10,B102,B103,B105,B107,B108,B114,B115,B118,B119,B125,B127,B129,B13,B132,B136,B137,B14,B15,B16,B17,B18,B21,B24,B28,B3,B35,B39,B40,B41,B42,B43,B44,B45,B47,B48,B49,B54,B56,B58,B59,B61,B62,B63,B69,B7,B71,B72,B73,B74,B77,B81,B82,B83,B84,B87,B94,C1,C14,C16,C18,C2,C20,C22,C24,C26,C27,C28,C29,C32,C33,C34,C36,C39,C41,C44,C46,C47,C49,C5,C50,C53,C54,C55,C57,C59,C6,C60,C67,C69,C73,C74,C76,C77,C79,C8,C85,C86,D1,D3,D5,D7,D9
`Chr4:32762298`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B73,D1
`Chr4:32762361`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B76,D7
`Chr4:32762841`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B104,B138,B31
`Chr4:32762877`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A2,A8

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057806268.1

592 aa

296

592

TPP_enzyme_N

TPP_enzyme_M

TPP_enzyme_C

PF02776 TPP_enzyme_N 27-132 aa PF00205 TPP_enzyme_M 224-341 aa PF02775 TPP_enzyme_C 438-563 aa

XP_057806269.1

588 aa

294

588

TPP_enzyme_N

TPP_enzyme_M

TPP_enzyme_C

PF02776 TPP_enzyme_N 27-132 aa PF00205 TPP_enzyme_M 224-341 aa PF02775 TPP_enzyme_C 434-559 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057806268.1`	Pfam	`PF02776`	TPP_enzyme_N	Domain	27	132	2.2e-30	105.6	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
`XP_057806268.1`	Pfam	`PF00205`	TPP_enzyme_M	Domain	224	341	6.6e-23	81.7	Thiamine pyrophosphate enzyme, central domain
`XP_057806268.1`	Pfam	`PF02775`	TPP_enzyme_C	Domain	438	563	3.7e-14	53.5	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
`XP_057806269.1`	Pfam	`PF02776`	TPP_enzyme_N	Domain	27	132	2.2e-30	105.6	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
`XP_057806269.1`	Pfam	`PF00205`	TPP_enzyme_M	Domain	224	341	6.5e-23	81.7	Thiamine pyrophosphate enzyme, central domain
`XP_057806269.1`	Pfam	`PF02775`	TPP_enzyme_C	Domain	434	559	4.9e-14	53.1	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057950286.1
CCACAACCACAACCACATTCTTCCCTATCGCCATGGACACTACCCTAAGCTCCATCGACTCATGCAAACCGGGGGGGTCCCACCACGGCCCCCCTGCGGCCCCCGACGCCACCCTCGGCCGCCACGTGGCCCGCCGCCTCGTCCAGATCGGCGTGGAGGACGTCTTCACCGTCCCGGGCGACTTCAACCTCACCCTCCTCGACCACCTCATCGCCGAGCCCGGCCTCACCAACGTCGGCTGTTGCAACGAGCTCAACGCC...

XM_057950285.1
CCACAACCACAACCACATTCTTCCCTATCGCCATGGACACTACCCTAAGCTCCATCGACTCATGCAAACCGGGGGGGTCCCACCACGGCCCCCCTGCGGCCCCCGACGCCACCCTCGGCCGCCACGTGGCCCGCCGCCTCGTCCAGATCGGCGTGGAGGACGTCTTCACCGTCCCGGGCGACTTCAACCTCACCCTCCTCGACCACCTCATCGCCGAGCCCGGCCTCACCAACGTCGGCTGTTGCAACGAGCTCAACGCC...

CDS

2 records

下载 CDS FASTA

LOC131021189
ATGGACACTACCCTAAGCTCCATCGACTCATGCAAACCGGGGGGGTCCCACCACGGCCCCCCTGCGGCCCCCGACGCCACCCTCGGCCGCCACGTGGCCCGCCGCCTCGTCCAGATCGGCGTGGAGGACGTCTTCACCGTCCCGGGCGACTTCAACCTCACCCTCCTCGACCACCTCATCGCCGAGCCCGGCCTCACCAACGTCGGCTGTTGCAACGAGCTCAACGCCGGCTACGCGGCCGACGGCTACGCCCGTGCCCG...

Protein

2 records

下载 Protein FASTA

XP_057806268.1
MDTTLSSIDSCKPGGSHHGPPAAPDATLGRHVARRLVQIGVEDVFTVPGDFNLTLLDHLIAEPGLTNVGCCNELNAGYAADGYARARGVGACVVTFTVGGLSVINAIAGAYSENLPVICIVGGPNTNDYGTNRILHHTIGLPDFSQELKCFKPVTCYQAVVNNLDDAHEQIDRAISIALMESKPVYISISCNLPGLPHPTFARDPIPFALSPRSSNKLGLEAAVNAAAEFLNKAVKPVMIGGPKLRLAKAGRAFVELADA...

XP_057806269.1
MDTTLSSIDSCKPGGSHHGPPAAPDATLGRHVARRLVQIGVEDVFTVPGDFNLTLLDHLIAEPGLTNVGCCNELNAGYAADGYARARGVGACVVTFTVGGLSVINAIAGAYSENLPVICIVGGPNTNDYGTNRILHHTIGLPDFSQELKCFKPVTCYQAVVNNLDDAHEQIDRAISIALMESKPVYISISCNLPGLPHPTFARDPIPFALSPRSSNKLGLEAAVNAAAEFLNKAVKPVMIGGPKLRLAKAGRAFVELADA...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

下载 upstream 下载 downstream 下载 upstream + gene + downstream

JBrowse

跳转到基因组浏览器