Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G002046`

染色体: Chr04 坐标: 33190550-33197467 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G002046`
名称	SmilChr04G002046
描述	alpha-mannosidase I MNS5
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	33190550 - 33197467 / `-`

ID 对照

NCBI Gene ID	`LOC131021215`
GeneID	`131021215`
locus_tag	`-`
NCBI Name	`LOC131021215`
原始查询	`SmilChr04G002046`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	alpha-mannosidase I MNS5
产物	alpha-mannosidase I MNS5
Arabidopsis	`AT1G27520` (AT1G27520) Glycosyl hydrolase family 47 protein [Source:NCBI gene (formerly Entrezgene);Acc:839643] identity=76.4; qcov=0.996; evalue=0; confidence=high
Rice	`Os02g0741300` - identity=76.5; qcov=1; evalue=0; confidence=high
GO	GO:0004571 (mannosyl-oligosaccharide 1,2-alpha-mannosidase activity); GO:0005509 (calcium ion binding); GO:0005783 (endoplasmic reticulum); GO:0005975 (carbohydrate metabolic process); GO:0016020 (membrane); GO:1904380 (endoplasmic reticulum mannose trimming); GO:1904382 (mannose trimming involved in glycoprotein ERAD pathway)
KEGG	smil04141 (Protein processing in endoplasmic reticulum - Salvia miltiorrhiza (redroot sage))
Pfam	PF01532 (Glyco_hydro_47)
InterPro	-
eggNOG	-
NR	GeneID:131021215

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Endoplasmic reticulum	内质网	1.00000	`XP_057806299.1`
2	Endoplasmic reticulum membrane	内质网膜	0.60000	`XP_057806299.1`
3	Endoplasmic reticulum lumen	内质网腔	0.40000	`XP_057806300.1`
4	Nucleus	细胞核	0.00000	`XP_057806299.1`
5	Chromosome	染色体	0.00000	`XP_057806299.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:33190843`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B138,C47
`Chr4:33190894`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B5,C83
`Chr4:33190968`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B131,B91,C67
`Chr4:33190974`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	A11,C1,C72
`Chr4:33191654`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr4:33191745`	`G`	`GGT`	2bp_insertion	frameshift_variant	29	A2,A25,A9,B12,B120,B122,B14,B20,B25,B32,B40,B5,B54,B59,B60,B67,B90,C12,C14,C19,C27,C32,C34,C4,C55,C6,C72,D1,D2
`Chr4:33191750`	`AGG`	`A`	2bp_deletion	frameshift_variant	27	A2,A25,A9,B12,B120,B122,B14,B20,B25,B32,B40,B5,B54,B59,B60,B67,C12,C14,C19,C27,C34,C4,C55,C6,C72,D1,D2
`Chr4:33191990`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A24,B7,C42,C8
`Chr4:33193093`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C32,C68
`Chr4:33193891`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B88
`Chr4:33195438`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B46
`Chr4:33195715`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B39,B85,C13

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057806299.1

575 aa

288

575

Glyco_hydro_47

PF01532 Glyco_hydro_47 46-480 aa

XP_057806300.1

469 aa

234

469

Glyco_hydro_47

PF01532 Glyco_hydro_47 1-374 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057806299.1`	Pfam	`PF01532`	Glyco_hydro_47	Repeat	46	480	1.7e-114	384.0	Glycosyl hydrolase family 47
`XP_057806300.1`	Pfam	`PF01532`	Glyco_hydro_47	Repeat	1	374	9.6e-98	328.8	Glycosyl hydrolase family 47

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057950316.1
AGCGCTAATTATGTAAGAATAATACTATACGTTAATTGCACATTAATCTCGCACAGTAATTTTTAATTTTGATTTAATTTAAGAAGCAAAATAGTAGCTGTTCCGGAAAAGAGAGAAGAAGCTCAAGAGCAAACACAAAATAAGTGAGAAGCCTATCCCAAACCCCCCCAAAAACCATATATACTCGTAACTTTCAAGGGTAATTTCGAAGTCCCATTTGCTCAAATACTATTATCGGCTTCCATTTTTGCGCGCACGGA...

XM_057950317.1
TGGCGATTTTTTCCACATTTTACATCGAAATCGCTTCGTCAAAGCCAGACCCGTATGCAGCTAAGAAGAAGCGGATGAGCGAAAAAGTCCGCCAGATGTTTTACCATGCCTATGACAACTATATGATGTATGCTTTCCCGATGACTTATTTCTCAGCACGATGAATTGAGGCCTCTGACAAAATCGTTCACGGATTCTCTAAGTGAGCTTGGAAATCTGAAGCTTGAACATCTGCCACAAGAGTATAATGGTTCAGCACT...

CDS

2 records

下载 CDS FASTA

LOC131021215
ATGTTACTTGGAAAGAGATGGGCATCGTTTCTGATATTTATGGCGATTTTTTCCACATTTTACATCGAAATCGCTTCGTCAAAGCCAGACCCGTATGCAGCTAAGAAGAAGCGGATGAGCGAAAAAGTCCGCCAGATGTTTTACCATGCCTATGACAACTATATGATGTATGCTTTCCCGCACGATGAATTGAGGCCTCTGACAAAATCGTTCACGGATTCTCTAAGTGAGCTTGGAAATCTGAAGCTTGAACATCTGCC...

LOC131021215
ATGGGAAACAATACCGAGTTTGAGAAGGGAGTTCTTTGGTTATCCGAGAATCTAACATTTGATGTTGATGCTAGGATAAATCTCTTTGAGTGCAACATAAGAGTACTTGGAGGACTTGTGTCTGCTCATATTCTTGCAACTGATTCTACAAACAGGTTAACTAAAGGAACTTATAGTAATCAACTTCTTGTTCTGGCTGAGGAGTTGGGACAGCGTTTTTTACCTGCATTTGATACCCCTACTGGACTGCCTTACGCTTG...

Protein

2 records

下载 Protein FASTA

XP_057806299.1
MLLGKRWASFLIFMAIFSTFYIEIASSKPDPYAAKKKRMSEKVRQMFYHAYDNYMMYAFPHDELRPLTKSFTDSLSELGNLKLEHLPQEYNGSALTLIESLSSLVIMGNNTEFEKGVLWLSENLTFDVDARINLFECNIRVLGGLVSAHILATDSTNRLTKGTYSNQLLVLAEELGQRFLPAFDTPTGLPYAWINLKHGVMENEITETSTSGCGSLILEMGALSHLTGDPRFESAAFRALRKLWGMRSSLNLVGTTLDVE...

XP_057806300.1
MGNNTEFEKGVLWLSENLTFDVDARINLFECNIRVLGGLVSAHILATDSTNRLTKGTYSNQLLVLAEELGQRFLPAFDTPTGLPYAWINLKHGVMENEITETSTSGCGSLILEMGALSHLTGDPRFESAAFRALRKLWGMRSSLNLVGTTLDVETGEWIEFSSGIGAGVDSFYEYLLKAHILFGREELWRMFQPAYTAVQKYFRHGPWYHEADMRTGRATYWQLTSLQAFWPGLQVLLGDVAAANSSHREFFYVWQKFGV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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