Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G002103`

染色体: Chr04 坐标: 33942886-33954239 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G002103`
名称	SmilChr04G002103
描述	endoribonuclease Dicer homolog 1-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	33942886 - 33954239 / `-`

ID 对照

NCBI Gene ID	`LOC131021268`
GeneID	`131021268`
locus_tag	`-`
NCBI Name	`LOC131021268`
原始查询	`SmilChr04G002103`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	endoribonuclease Dicer homolog 1-like
产物	endoribonuclease Dicer homolog 1-like
Arabidopsis	`AT1G01040` (DCL1) dicer-like 1 [Source:NCBI gene (formerly Entrezgene);Acc:839574] identity=72.5; qcov=1; evalue=0; confidence=high
Rice	`Os03g0121800` (DCL1) - identity=75.4; qcov=0.896; evalue=0; confidence=high
GO	GO:0003723 (RNA binding); GO:0004525 (ribonuclease III activity); GO:0005515 (protein binding); GO:0005524 (ATP binding); GO:0005634 (nucleus); GO:0005737 (cytoplasm); GO:0030422 (siRNA processing)
KEGG	-
Pfam	PF00035 (dsrm); PF00270 (DEAD); PF00271 (Helicase_C); PF00636 (Ribonuclease_3); PF02170 (PAZ); PF03368 (Dicer_dimer); PF04851 (ResIII); PF14622 (Ribonucleas_3_3); PF14709 (DND1_DSRM)
InterPro	-
eggNOG	-
NR	GeneID:131021268

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057806367.1`
2	Chromosome	染色体	0.00000	`XP_057806367.1`
3	Centromere	着丝粒	0.00000	`XP_057806367.1`
4	Chromatin	染色质	0.00000	`XP_057806367.1`
5	Telomere	端粒	0.00000	`XP_057806367.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:33943180`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B38
`Chr4:33943216`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B22,C77
`Chr4:33945108`	`TC`	`T`	1bp_deletion	frameshift_variant	1	C11
`Chr4:33945108`	`TC`	`T`	1bp_deletion	CDS_variant	1	C11
`Chr4:33945238`	`CA`	`C`	1bp_deletion	frameshift_variant	1	A21
`Chr4:33945238`	`CA`	`C`	1bp_deletion	CDS_variant	1	A21
`Chr4:33946394`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D6
`Chr4:33946449`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B127,B44,C36
`Chr4:33946554`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B8,B90,B92,C31
`Chr4:33946634`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A25,B14
`Chr4:33947165`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B57,C27,C55
`Chr4:33948121`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B126,B133

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057806367.1

1930 aa

965

1930

ResIII

DEAD

Helicase_C

Dicer_dimer

PAZ

Ribonuclease_3

Ribonucleas_3_3

Ribonuclease_3

dsrm

DND1_DSRM

dsrm

PF04851 ResIII 270-435 aa PF00270 DEAD 271-435 aa PF00271 Helicase_C 671-788 aa PF03368 Dicer_dimer 863-952 aa PF02170 PAZ 1232-1365 aa PF00636 Ribonuclease_3 1403-1549 aa PF14622 Ribonucleas_3_3 1603-1742 aa PF00636 Ribonuclease_3 1625-1738 aa PF00035 dsrm 1765-1825 aa PF14709 DND1_DSRM 1852-1925 aa PF00035 dsrm 1855-1925 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057806367.1`	Pfam	`PF04851`	ResIII	Family	270	435	6e-16	59.5	Type III restriction enzyme, res subunit
`XP_057806367.1`	Pfam	`PF00270`	DEAD	Domain	271	435	4.3e-17	63.1	DEAD/DEAH box helicase
`XP_057806367.1`	Pfam	`PF00271`	Helicase_C	Domain	671	788	9.3e-18	65.2	Helicase conserved C-terminal domain
`XP_057806367.1`	Pfam	`PF03368`	Dicer_dimer	Domain	863	952	1.9e-25	89.4	Dicer dimerisation domain
`XP_057806367.1`	Pfam	`PF02170`	PAZ	Domain	1232	1365	7.8e-19	68.5	PAZ domain
`XP_057806367.1`	Pfam	`PF00636`	Ribonuclease_3	Family	1403	1549	1.6e-45	154.7	Ribonuclease III domain
`XP_057806367.1`	Pfam	`PF14622`	Ribonucleas_3_3	Family	1603	1742	1.2e-29	103.7	Ribonuclease-III-like
`XP_057806367.1`	Pfam	`PF00636`	Ribonuclease_3	Family	1625	1738	1.6e-45	154.7	Ribonuclease III domain
`XP_057806367.1`	Pfam	`PF00035`	dsrm	Domain	1765	1825	1.3e-18	68.0	Double-stranded RNA binding motif
`XP_057806367.1`	Pfam	`PF14709`	DND1_DSRM	Domain	1852	1925	1.7e-17	64.2	double strand RNA binding domain from DEAD END PROTEIN 1
`XP_057806367.1`	Pfam	`PF00035`	dsrm	Domain	1855	1925	1.3e-18	68.0	Double-stranded RNA binding motif

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057950384.1
GTATATTAGTTGTCGGAACCAATTCGGAATCGAAGAATCGGGGGCGCGAAGAGAATTAGGGATTTGAGCTGTTGGATGGAAGAAGAGAAGAGAAGAGAAGAGAGAGCAGAGTGGCGTAAGATAGACCGGTGGGGGAAGGAATCTTCGAATCACACAATTTGCTTTGGTTGCTACTTGCTCTATCTTCGCGTGCTTCATACGGTCTATTTCACGCTTATCTGCTTTCTCCCCTCTCTCTAACTCGCTCTTTCTCTCTCTGA...

CDS

1 records

下载 CDS FASTA

LOC131021268
ATGGGAGAGGAAGCTGGGAGTCCAGCTAATGCTTGTAATCTCGATGCTAATGGCAGACCTTCGTACTGGTTAGATGCTTGTGAGGATGTGTCGTGTGATGATTACTTTGTTGATTTTGGACCTGTCACAGCCAATTCAGTTCCAGACCCGGAACCACACTCCCAGGGAGGCTGCAATGATCCTTGTTTCTTTGGCGGAATCGATCAGATTCTTGACAGCATAAAGAACGGTGGCACAGACATGCCTAACCATAATTGCAC...

Protein

1 records

下载 Protein FASTA

XP_057806367.1
MGEEAGSPANACNLDANGRPSYWLDACEDVSCDDYFVDFGPVTANSVPDPEPHSQGGCNDPCFFGGIDQILDSIKNGGTDMPNHNCTNGSVNGTHNSSAQQACVQDQHSPSKSAVINGNGQRLAVSSNSCKNEKTNLGKRSHEVNDVEQRRDKRARGRDPKERKIWDRAPSRKRLRGWDDMETDGQRRDQVRRRERHGTGNWKDRDHREARGYWEREKETNELVFRTGSWEACKNRDEKANAHKNNKYSGCAEETKPEQP...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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