Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G002285`

染色体: Chr04 坐标: 37103580-37105514 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G002285`
名称	SmilChr04G002285
描述	MDIS1-interacting receptor like kinase 2-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	37103580 - 37105514 / `-`

ID 对照

NCBI Gene ID	`LOC131023383`
GeneID	`131023383`
locus_tag	`-`
NCBI Name	`LOC131023383`
原始查询	`SmilChr04G002285`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	MDIS1-interacting receptor like kinase 2-like
产物	MDIS1-interacting receptor like kinase 2-like
Arabidopsis	`AT4G08850` (AT4G08850) Leucine-rich repeat receptor-like protein kinase family protein [Source:NCBI gene (formerly Entrezgene);Acc:826456] identity=35.9; qcov=0.873; evalue=2.1e-98; confidence=medium
Rice	`Os10g0119200` - identity=34.2; qcov=0.925; evalue=8.34e-88; confidence=low
GO	GO:0004672 (protein kinase activity); GO:0005515 (protein binding); GO:0005524 (ATP binding); GO:0005886 (plasma membrane); GO:0006468 (protein phosphorylation); GO:0009755 (hormone-mediated signaling pathway)
KEGG	-
Pfam	PF00069 (Pkinase); PF00560 (LRR_1); PF07714 (PK_Tyr_Ser-Thr); PF13855 (LRR_8)
InterPro	-
eggNOG	-
NR	GeneID:131023383

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cell membrane	细胞膜	1.00000	`XP_057808905.1`
2	Nucleus	细胞核	0.00000	`XP_057808905.1`
3	Chromosome	染色体	0.00000	`XP_057808905.1`
4	Centromere	着丝粒	0.00000	`XP_057808905.1`
5	Chromatin	染色质	0.00000	`XP_057808905.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:37103597`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B138,B23,B96
`Chr4:37103603`	`G`	`A`	EMS_canonical_SNV	stop_gained	2	B132,C46
`Chr4:37103603`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B132,C46
`Chr4:37103624`	`C`	`CT`	1bp_insertion	frameshift_variant	1	B3
`Chr4:37103624`	`C`	`CT`	1bp_insertion	CDS_variant	1	B3
`Chr4:37103645`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B3
`Chr4:37103672`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B31
`Chr4:37103675`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B98
`Chr4:37103774`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C1
`Chr4:37103811`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A4
`Chr4:37103823`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	B113,B128,B2,B86
`Chr4:37103824`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B103,B63,B86,C25,C8

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057808905.1

644 aa

322

644

LRR_8

LRR_1

LRR_8

LRR_1

LRR_8

LRR_1

PK_Tyr_Ser-Thr

Pkinase

PF13855 LRR_8 84-143 aa PF00560 LRR_1 109-131 aa PF00560 LRR_1 163-184 aa PF00560 LRR_1 186-208 aa PF13855 LRR_8 186-243 aa PF00560 LRR_1 210-232 aa PF00560 LRR_1 265-287 aa PF13855 LRR_8 288-348 aa PF00560 LRR_1 289-311 aa PF00560 LRR_1 314-332 aa PF00560 LRR_1 391-409 aa PF07714 PK_Tyr_Ser-Thr 523-620 aa PF00069 Pkinase 524-615 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057808905.1`	Pfam	`PF13855`	LRR_8	Repeat	84	143	9.5e-30	102.9	Leucine rich repeat
`XP_057808905.1`	Pfam	`PF00560`	LRR_1	Repeat	109	131	7.6e-32	103.2	Leucine Rich Repeat
`XP_057808905.1`	Pfam	`PF00560`	LRR_1	Repeat	163	184	7.6e-32	103.2	Leucine Rich Repeat
`XP_057808905.1`	Pfam	`PF00560`	LRR_1	Repeat	186	208	7.6e-32	103.2	Leucine Rich Repeat
`XP_057808905.1`	Pfam	`PF13855`	LRR_8	Repeat	186	243	9.5e-30	102.9	Leucine rich repeat
`XP_057808905.1`	Pfam	`PF00560`	LRR_1	Repeat	210	232	7.6e-32	103.2	Leucine Rich Repeat
`XP_057808905.1`	Pfam	`PF00560`	LRR_1	Repeat	265	287	7.6e-32	103.2	Leucine Rich Repeat
`XP_057808905.1`	Pfam	`PF13855`	LRR_8	Repeat	288	348	9.5e-30	102.9	Leucine rich repeat
`XP_057808905.1`	Pfam	`PF00560`	LRR_1	Repeat	289	311	7.6e-32	103.2	Leucine Rich Repeat
`XP_057808905.1`	Pfam	`PF00560`	LRR_1	Repeat	314	332	7.6e-32	103.2	Leucine Rich Repeat
`XP_057808905.1`	Pfam	`PF00560`	LRR_1	Repeat	391	409	7.6e-32	103.2	Leucine Rich Repeat
`XP_057808905.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	523	620	3.3e-15	56.8	Protein tyrosine and serine/threonine kinase
`XP_057808905.1`	Pfam	`PF00069`	Pkinase	Domain	524	615	2.5e-13	50.8	Protein kinase domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

1 records

下载 cDNA FASTA

XM_057952922.1
ATGGATTTTGGGATAAGTAGTCGCATTTTGATCATGGCCATAGTGTTGATGAAAGCAGCAGAAGCAAGCATGAGCAGAGAGATGCAGGCATTGATGAATTTTGGGTGGCCTCACAACTCCACAACTCATCACTGCAATTGGATTGGCATTACTTGTGATGATGCTGCTCATGTTGCGGCGATGAGCCTCCAAGTTTGCCCTTATCCTACTATTCCTCTTAGTTTAAACCATTTTGATGTGTTTGCTTTTCCACATCTCAC...

CDS

1 records

下载 CDS FASTA

LOC131023383
ATGGATTTTGGGATAAGTAGTCGCATTTTGATCATGGCCATAGTGTTGATGAAAGCAGCAGAAGCAAGCATGAGCAGAGAGATGCAGGCATTGATGAATTTTGGGTGGCCTCACAACTCCACAACTCATCACTGCAATTGGATTGGCATTACTTGTGATGATGCTGCTCATGTTGCGGCGATGAGCCTCCAAGTTTGCCCTTATCCTACTATTCCTCTTAGTTTAAACCATTTTGATGTGTTTGCTTTTCCACATCTCAC...

Protein

1 records

下载 Protein FASTA

XP_057808905.1
MDFGISSRILIMAIVLMKAAEASMSREMQALMNFGWPHNSTTHHCNWIGITCDDAAHVAAMSLQVCPYPTIPLSLNHFDVFAFPHLTRIHLTSYCLKGTIPPQIGYLSNLTYLNLSDNPLNSELPVSLANLTELQILDISHNDHMSYGIYGAIPPEIGSLSKLAHLNLSYNELNTHLPLSLANLTNLHVLDLSYNSIVGVIPPEIGSLSKLTYLKLCHNPLNGELPVSLANLTELQILDISHSRRFYDINGIYGVIPPEI...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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