Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G002376`

染色体: Chr04 坐标: 38263081-38275621 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G002376`
名称	SmilChr04G002376
描述	general negative regulator of transcription subunit 3
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	38263081 - 38275621 / `-`

ID 对照

NCBI Gene ID	`LOC131021508`
GeneID	`131021508`
locus_tag	`-`
NCBI Name	`LOC131021508`
原始查询	`SmilChr04G002376`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	general negative regulator of transcription subunit 3
产物	general negative regulator of transcription subunit 3
Arabidopsis	`AT5G18230` (AT5G18230) transcription regulator NOT2/NOT3/NOT5 family protein [Source:NCBI gene (formerly Entrezgene);Acc:831941] identity=61.2; qcov=1.06; evalue=0; confidence=high
Rice	`Os03g0652100` - identity=58.5; qcov=1.08; evalue=0; confidence=high
GO	GO:0000289 (nuclear-transcribed mRNA poly(A) tail shortening); GO:0000932 (P-body); GO:0005634 (nucleus); GO:0006355 (regulation of DNA-templated transcription); GO:0030015 (CCR4-NOT core complex)
KEGG	smil03018 (RNA degradation - Salvia miltiorrhiza (redroot sage))
Pfam	PF04065 (Not3); PF04153 (NOT2_3_5_C)
InterPro	-
eggNOG	-
NR	GeneID:131021508

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057806706.1`
2	Cytoplasmic granule	细胞质颗粒	1.00000	`XP_057806708.1`
3	Nucleus	细胞核	0.80000	`XP_057806706.1`
4	P-body	P-body	0.60000	`XP_057806708.1`
5	Cytoplasmic ribonucleoprotein granule	Cytoplasmic ribonucleoprotein granule	0.60000	`XP_057806713.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:38264937`	`A`	`AC`	1bp_insertion	frameshift_variant	1	B50
`Chr4:38264937`	`A`	`AC`	1bp_insertion	CDS_variant	1	B50
`Chr4:38264998`	`CA`	`C`	1bp_deletion	frameshift_variant	2	A16,C24
`Chr4:38264998`	`CA`	`C`	1bp_deletion	CDS_variant	2	A16,C24
`Chr4:38265347`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B59,C81
`Chr4:38265663`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B30
`Chr4:38266092`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A21,B1,B54,C35
`Chr4:38266129`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	A22,B117,C49
`Chr4:38269265`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	A15,C23
`Chr4:38269279`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B59,C81
`Chr4:38269556`	`G`	`A`	EMS_canonical_SNV	CDS_variant	4	A23,B130,B58,B69
`Chr4:38269711`	`GGA`	`G`	2bp_deletion	frameshift_variant	1	B137

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057806706.1

891 aa

446

891

Not3

NOT2_3_5_C

PF04065 Not3 4-235 aa PF04153 NOT2_3_5_C 728-840 aa

XP_057806707.1

884 aa

442

884

Not3

NOT2_3_5_C

PF04065 Not3 4-228 aa PF04153 NOT2_3_5_C 721-833 aa

XP_057806708.1

870 aa

435

870

Not3

NOT2_3_5_C

PF04065 Not3 4-235 aa PF04153 NOT2_3_5_C 728-864 aa

XP_057806709.1

868 aa

434

868

Not3

NOT2_3_5_C

PF04065 Not3 4-235 aa PF04153 NOT2_3_5_C 705-817 aa

XP_057806710.1

863 aa

432

863

Not3

NOT2_3_5_C

PF04065 Not3 4-228 aa PF04153 NOT2_3_5_C 721-857 aa

XP_057806711.1

861 aa

430

861

Not3

NOT2_3_5_C

PF04065 Not3 4-228 aa PF04153 NOT2_3_5_C 698-810 aa

XP_057806713.1

847 aa

424

847

Not3

NOT2_3_5_C

PF04065 Not3 4-235 aa PF04153 NOT2_3_5_C 705-841 aa

XP_057806714.1

840 aa

420

840

Not3

NOT2_3_5_C

PF04065 Not3 4-228 aa PF04153 NOT2_3_5_C 698-834 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057806706.1`	Pfam	`PF04065`	Not3	Family	4	235	7.6e-84	281.4	Not1 N-terminal domain, CCR4-Not complex component
`XP_057806706.1`	Pfam	`PF04153`	NOT2_3_5_C	Domain	728	840	7.9e-29	101.0	NOT2/NOT3/NOT5 C-terminal
`XP_057806707.1`	Pfam	`PF04065`	Not3	Family	4	228	2.6e-86	289.4	Not1 N-terminal domain, CCR4-Not complex component
`XP_057806707.1`	Pfam	`PF04153`	NOT2_3_5_C	Domain	721	833	7.9e-29	101.0	NOT2/NOT3/NOT5 C-terminal
`XP_057806708.1`	Pfam	`PF04065`	Not3	Family	4	235	7.2e-84	281.5	Not1 N-terminal domain, CCR4-Not complex component
`XP_057806708.1`	Pfam	`PF04153`	NOT2_3_5_C	Domain	728	864	4e-33	114.9	NOT2/NOT3/NOT5 C-terminal
`XP_057806709.1`	Pfam	`PF04065`	Not3	Family	4	235	7.2e-84	281.5	Not1 N-terminal domain, CCR4-Not complex component
`XP_057806709.1`	Pfam	`PF04153`	NOT2_3_5_C	Domain	705	817	7.7e-29	101.1	NOT2/NOT3/NOT5 C-terminal
`XP_057806710.1`	Pfam	`PF04065`	Not3	Family	4	228	2.5e-86	289.5	Not1 N-terminal domain, CCR4-Not complex component
`XP_057806710.1`	Pfam	`PF04153`	NOT2_3_5_C	Domain	721	857	4e-33	114.9	NOT2/NOT3/NOT5 C-terminal
`XP_057806711.1`	Pfam	`PF04065`	Not3	Family	4	228	2.5e-86	289.5	Not1 N-terminal domain, CCR4-Not complex component
`XP_057806711.1`	Pfam	`PF04153`	NOT2_3_5_C	Domain	698	810	7.6e-29	101.1	NOT2/NOT3/NOT5 C-terminal
`XP_057806713.1`	Pfam	`PF04065`	Not3	Family	4	235	6.8e-84	281.5	Not1 N-terminal domain, CCR4-Not complex component
`XP_057806713.1`	Pfam	`PF04153`	NOT2_3_5_C	Domain	705	841	3.9e-33	114.9	NOT2/NOT3/NOT5 C-terminal
`XP_057806714.1`	Pfam	`PF04065`	Not3	Family	4	228	2.4e-86	289.6	Not1 N-terminal domain, CCR4-Not complex component
`XP_057806714.1`	Pfam	`PF04153`	NOT2_3_5_C	Domain	698	834	3.8e-33	115.0	NOT2/NOT3/NOT5 C-terminal

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

8 records

下载 cDNA FASTA

XM_057950730.1
AATTGATCCTCTCTGTCGTATCAAACCCCAACATTTTTCCGGCTGAGGTTTCTCATCGCTTAAAAAGAAAAAAAGAAAAGAAAATACTAATAATAAACGTCGTGACGTGCCAACTTATTAATTAATTAAATAAATAATTTCCTCGCAATCACTATAGAGCGAAGCTGAACTGATTTCCTTCTCCTTCAATTGAAACCCTAGGGTTTTTGGATGAACTTTTCCTAAATTGTTGTTTGGTTATTGGAAAATCGGCAATGGGA...

XM_057950726.1
AATTGATCCTCTCTGTCGTATCAAACCCCAACATTTTTCCGGCTGAGGTTTCTCATCGCTTAAAAAGAAAAAAAGAAAAGAAAATACTAATAATAAACGTCGTGACGTGCCAACTTATTAATTAATTAAATAAATAATTTCCTCGCAATCACTATAGAGCGAAGCTGAACTGATTTCCTTCTCCTTCAATTGAAACCCTAGGGTTTTTGGATGAACTTTTCCTAAATTGTTGTTTGGTTATTGGAAAATCGGCAATGGGA...

CDS

8 records

下载 CDS FASTA

LOC131021508
ATGGGAGCAAGCCGGAAGTTGCAGGGAGAGATAGATCGAGTTTTGAAGAAGGTTCAAGAAGGCGTCGACGTGTTCGACAGCATTTGGAACAAGGTTTATGATACAGACAATGCGAATCAGAAGGAAAAATTCGAGGCCGACTTGAAAAAGGAGATTAAGAAGTTGCAGAGGTATAGAGACCAGATCAAGACATGGATACAGTCCAGCGAGATCAAGGATAAGAAGGCTCTGATGGATGCTCGAAAACAAATTGAGCGTGA...

Protein

8 records

下载 Protein FASTA

XP_057806706.1
MGASRKLQGEIDRVLKKVQEGVDVFDSIWNKVYDTDNANQKEKFEADLKKEIKKLQRYRDQIKTWIQSSEIKDKKVSASYEQALMDARKQIEREMERFKICEKETKTKAFSKEGLGQQPKTDPKEKAKSETRDWLNNVVSELENQIDSFEAEIEGLSVKKGKTRPPRLTHLEASITRHKAHIMKLELILRLLDNDELSPEQVNDVKDFLDDYVERNQEDFDEFSDVDELYSSLPLDKVESLEDLVTGPPSLVKGVTASSA...

XP_057806707.1
MGASRKLQGEIDRVLKKVQEGVDVFDSIWNKVYDTDNANQKEKFEADLKKEIKKLQRYRDQIKTWIQSSEIKDKKALMDARKQIEREMERFKICEKETKTKAFSKEGLGQQPKTDPKEKAKSETRDWLNNVVSELENQIDSFEAEIEGLSVKKGKTRPPRLTHLEASITRHKAHIMKLELILRLLDNDELSPEQVNDVKDFLDDYVERNQEDFDEFSDVDELYSSLPLDKVESLEDLVTGPPSLVKGVTASSAVITMKTS...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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