Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G002421`

染色体: Chr04 坐标: 38838648-38845774 链方向: - 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G002421`
名称	SmilChr04G002421
描述	casein kinase II subunit alpha-2-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	38838648 - 38845774 / `-`

ID 对照

NCBI Gene ID	`LOC131021548`
GeneID	`131021548`
locus_tag	`-`
NCBI Name	`LOC131021548`
原始查询	`SmilChr04G002421`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	casein kinase II subunit alpha-2-like
产物	casein kinase II subunit alpha-2-like
Arabidopsis	`AT2G23070` (AT2G23070) Protein kinase superfamily protein [Source:NCBI gene (formerly Entrezgene);Acc:816837] identity=91.9; qcov=0.828; evalue=0; confidence=high
Rice	`Os07g0114400` (OsCKA2-2) - identity=89.8; qcov=0.794; evalue=0; confidence=high
GO	GO:0004674 (protein serine/threonine kinase activity); GO:0005524 (ATP binding); GO:0005634 (nucleus); GO:0005829 (cytosol); GO:0005956 (protein kinase CK2 complex); GO:0006468 (protein phosphorylation)
KEGG	smil03008 (Ribosome biogenesis in eukaryotes - Salvia miltiorrhiza (redroot sage)); smil04712 (Circadian rhythm - plant - Salvia miltiorrhiza (redroot sage))
Pfam	PF00069 (Pkinase); PF01636 (APH); PF07714 (PK_Tyr_Ser-Thr)
InterPro	-
eggNOG	-
NR	GeneID:131021548

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057806765.1`
2	Cytoplasm	细胞质	1.00000	`XP_057806765.1`
3	Cytosol	细胞质基质	0.80000	`XP_057806765.1`
4	Nucleoplasm	核质	0.40000	`XP_057806765.1`
5	Chromosome	染色体	0.00000	`XP_057806765.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:38839453`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B100
`Chr4:38839771`	`C`	`CA`	1bp_insertion	frameshift_variant	11	A14,A20,B117,B118,B3,B44,B76,B86,B92,C58,C83
`Chr4:38839777`	`G`	`GAA`	2bp_insertion	frameshift_variant	2	B3,B86
`Chr4:38839777`	`G`	`GAA`	2bp_insertion	CDS_variant	2	B3,B86
`Chr4:38839950`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B124,B79
`Chr4:38840065`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	B115,B78,C2,C44,C49
`Chr4:38840134`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	C68
`Chr4:38845206`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B59,C81

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057806765.1

418 aa

209

418

Pkinase

PK_Tyr_Ser-Thr

APH

PF00069 Pkinase 119-404 aa PF07714 PK_Tyr_Ser-Thr 121-318 aa PF01636 APH 229-268 aa

XP_057806766.1

418 aa

209

418

Pkinase

PK_Tyr_Ser-Thr

APH

PF00069 Pkinase 119-404 aa PF07714 PK_Tyr_Ser-Thr 121-318 aa PF01636 APH 229-268 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057806765.1`	Pfam	`PF00069`	Pkinase	Domain	119	404	1.6e-62	212.0	Protein kinase domain
`XP_057806765.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	121	318	1.6e-18	67.7	Protein tyrosine and serine/threonine kinase
`XP_057806765.1`	Pfam	`PF01636`	APH	Domain	229	268	9.1e-07	29.6	Phosphotransferase enzyme family
`XP_057806766.1`	Pfam	`PF00069`	Pkinase	Domain	119	404	1.6e-62	212.0	Protein kinase domain
`XP_057806766.1`	Pfam	`PF07714`	PK_Tyr_Ser-Thr	Domain	121	318	1.6e-18	67.7	Protein tyrosine and serine/threonine kinase
`XP_057806766.1`	Pfam	`PF01636`	APH	Domain	229	268	9.1e-07	29.6	Phosphotransferase enzyme family

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XR_009100987.1
TAGGTAGTTACGAAATTCGGAAAGGAAATAGAAAAAGAAATACGAAAGGAGAAAAAGGGAAAAAGGGTTTCCATGGAAAAGAAGAGCAGCAGAGGAACGCAAATTATAATAACCCTTACCATTTGATGGCCGTAAGGCCTCTCCAATTCTTCGTGTCGCGCCACCACCCTCATCGCTCCTCGCCGCCCGGCCTCGTCCACCGTCTAGCATCCCCGCTCGCTCTAAACCACCACCAGAATATACACCACTACCGCCAGAAG...

XM_057950782.1
TAGGTAGTTACGAAATTCGGAAAGGAAATAGAAAAAGAAATACGAAAGGAGAAAAAGGGAAAAAGGGTTTCCATGGAAAAGAAGAGCAGCAGAGGAACGCAAATTATAATAACCCTTACCATTTGATGGCCGTAAGGCCTCTCCAATTCTTCGTGTCGCGCCACCACCCTCATCGCTCCTCGCCGCCCGGCCTCGTCCACCGTCTAGCATCCCCGCTCGCTCTAAACCACCACCAGAATATACACCACTACCGCCAGAAG...

CDS

2 records

下载 CDS FASTA

LOC131021548
ATGGCCGTAAGGCCTCTCCAATTCTTCGTGTCGCGCCACCACCCTCATCGCTCCTCGCCGCCCGGCCTCGTCCACCGTCTAGCATCCCCGCTCGCTCTAAACCACCACCAGAATATACACCACTACCGCCAGAAGGAAGAAGGCCAACCGCCGCCTCTGCCGCCGCCGGACCAGCAATTAACCTCCGTCAGCCGCCGCTCCCTGCTCGAAACCATGTCGCAGAAGATCGGGAAAGCGATTAGGCGGCCTGGAGCCCCGTC...

Protein

2 records

下载 Protein FASTA

XP_057806765.1
MAVRPLQFFVSRHHPHRSSPPGLVHRLASPLALNHHQNIHHYRQKEEGQPPPLPPPDQQLTSVSRRSLLETMSQKIGKAIRRPGAPSKARVYSDVNVIRPKEYWDYESLTVQWGEQDDYEVVRKVGRGKYSEVFEGIHVTNNEKCIIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQQSKTPSLIFEHVNNTDFKVLYPTLSDFDIRYYIYELLKALDYCHSQGIMHRDVKPHNVMIDHEQRKLRLIDWGLAE...

XP_057806766.1
MAVRPLQFFVSRHHPHRSSPPGLVHRLASPLALNHHQNIHHYRQKEEGQPPPLPPPDQQLTSVSRRSLLETMSQKIGKAIRRPGAPSKARVYSDVNVIRPKEYWDYESLTVQWGEQDDYEVVRKVGRGKYSEVFEGIHVTNNEKCIIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQQSKTPSLIFEHVNNTDFKVLYPTLSDFDIRYYIYELLKALDYCHSQGIMHRDVKPHNVMIDHEQRKLRLIDWGLAE...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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