Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G003298`

染色体: Chr04 坐标: 49700418-49706743 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G003298`
名称	SmilChr04G003298
描述	pyruvate dehydrogenase E1 component subunit beta-1, mitochondrial-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	49700418 - 49706743 / `+`

ID 对照

NCBI Gene ID	`LOC131020196`
GeneID	`131020196`
locus_tag	`-`
NCBI Name	`LOC131020196`
原始查询	`SmilChr04G003298`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	pyruvate dehydrogenase E1 component subunit beta-1, mitochondrial-like
产物	pyruvate dehydrogenase E1 component subunit beta-1%2C mitochondrial-like
Arabidopsis	`AT5G50850` (MAB1) Transketolase family protein [Source:NCBI gene (formerly Entrezgene);Acc:835157] identity=82.5; qcov=0.981; evalue=0; confidence=high
Rice	`Os08g0536000` - identity=83.7; qcov=1; evalue=0; confidence=high
GO	GO:0004739 (pyruvate dehydrogenase (acetyl-transferring) activity); GO:0005967 (GO:0005967); GO:0006086 (pyruvate decarboxylation to acetyl-CoA)
KEGG	smil00010 (Glycolysis / Gluconeogenesis - Salvia miltiorrhiza (redroot sage)); smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil00785 (Lipoic acid metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage)); smil01210 (2-Oxocarboxylic acid metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF02779 (Transket_pyr); PF02780 (Transketolase_C)
InterPro	-
eggNOG	-
NR	GeneID:131020196

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Mitochondrion	线粒体	1.00000	`XP_057804871.1`
2	Mitochondrion matrix	线粒体基质	1.00000	`XP_057804871.1`
3	Nucleus	细胞核	0.00000	`XP_057804871.1`
4	Chromosome	染色体	0.00000	`XP_057804871.1`
5	Centromere	着丝粒	0.00000	`XP_057804871.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:49702017`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B52
`Chr4:49705433`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B125,B90,B92,C37,C87
`Chr4:49705773`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	B130,B63,C12,C37,C53
`Chr4:49706082`	`TGA`	`T`	2bp_deletion	frameshift_variant	5	B122,B128,C33,C36,C40
`Chr4:49706082`	`TGA`	`T`	2bp_deletion	CDS_variant	5	B122,B128,C33,C36,C40
`Chr4:49706089`	`T`	`TA`	1bp_insertion	frameshift_variant	58	A10,A15,A22,A24,A3,A8,A9,B113,B119,B121,B123,B125,B133,B137,B138,B139,B16,B17,B20,B24,B32,B33,B37,B41,B44,B47,B6,B63,B66,B7,B72,B73,B76,B8,B80,B82,B9,B99,C1,C23,C25,C3,C30,C34,C41,C43,C44,C5,C53,C6,C67,C71,C72,C79,C84,D1,D4,D8
`Chr4:49706108`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B75,C40

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057804871.1

384 aa

192

384

Transket_pyr

Transketolase_C

PF02779 Transket_pyr 38-212 aa PF02780 Transketolase_C 232-350 aa

XP_057804872.1

372 aa

186

372

Transket_pyr

Transketolase_C

PF02779 Transket_pyr 38-212 aa PF02780 Transketolase_C 232-354 aa

XP_057804873.1

372 aa

186

372

Transket_pyr

Transketolase_C

PF02779 Transket_pyr 38-212 aa PF02780 Transketolase_C 232-354 aa

XP_057804874.1

372 aa

186

372

Transket_pyr

Transketolase_C

PF02779 Transket_pyr 38-212 aa PF02780 Transketolase_C 232-354 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057804871.1`	Pfam	`PF02779`	Transket_pyr	Domain	38	212	6.1e-44	150.4	Transketolase, pyrimidine binding domain
`XP_057804871.1`	Pfam	`PF02780`	Transketolase_C	Domain	232	350	4.7e-42	143.5	Transketolase, C-terminal domain
`XP_057804872.1`	Pfam	`PF02779`	Transket_pyr	Domain	38	212	5.6e-44	150.6	Transketolase, pyrimidine binding domain
`XP_057804872.1`	Pfam	`PF02780`	Transketolase_C	Domain	232	354	8e-43	146.0	Transketolase, C-terminal domain
`XP_057804873.1`	Pfam	`PF02779`	Transket_pyr	Domain	38	212	5.6e-44	150.6	Transketolase, pyrimidine binding domain
`XP_057804873.1`	Pfam	`PF02780`	Transketolase_C	Domain	232	354	8e-43	146.0	Transketolase, C-terminal domain
`XP_057804874.1`	Pfam	`PF02779`	Transket_pyr	Domain	38	212	5.6e-44	150.6	Transketolase, pyrimidine binding domain
`XP_057804874.1`	Pfam	`PF02780`	Transketolase_C	Domain	232	354	8e-43	146.0	Transketolase, C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

4 records

下载 cDNA FASTA

XM_057948891.1
GCTCCACCAACCCTTTCAAACTCGAGAGGCCAGATACAAATTATGCCTACTTAATTTTAAAGAGAAGGAAGGTGCCCACCAGCCACCAACGTACAACCAAAGCTGCGAATTGTGATATTTATATATATTTTCCCACTGGCAATATTCCTCTACGGTCCCTTCCCTACAGTAATTCAGCGGTTCCACCCTAGTCCTCCAGGTGTTGAGGATACTAGCGTCATTTAGGTACAACATACTAAAGCATAACCGTACAGAATCCT...

XM_057948889.1
CCAACGTACAACCAAAGCTGCGAATTGTGATATTTATATATATTTTCCCACTGGCAATATTCCTCTACGGTCCCTTCCCTACAGTAATTCAGCGGTTCCACCCTAGTCCTCCAGGTGTTGAGGATACTAGCGTCATTTAGGTACAACATACTAAAGCATAACCGTACAGAATCCTACGCTACAGACTAGAGAGAGTGGTACTCTGGAATTTGACCTGGGGCCGCCAAGCGGAAATAAAGCATTTCTATTAAGTGTGTCTG...

CDS

4 records

下载 CDS FASTA

LOC131020196
ATGTTGGGAGTTTTGAGGAGAACAGTTGCCTGCCAAGGCAATCATGCTTGGGGTTTGGAGCAAGGACTTCGAGTGATTGCATCTAGGACTCTTTCTTCTTCAGCAAAGGAGACGATGACAGTTCGTGATGCTTTAAACTCGGCACTTGATGAAGAGATGTCAGCTGATCCAAAAGTCTTTGTAATGGGTGAAGAGGTGGGCGAGTATCAGGGTGCATATAAGATTACAAAAGGGCTTCTTGACAAGTATGGTCCGGAGAG...

Protein

4 records

下载 Protein FASTA

XP_057804871.1
MLGVLRRTVACQGNHAWGLEQGLRVIASRTLSSSAKETMTVRDALNSALDEEMSADPKVFVMGEEVGEYQGAYKITKGLLDKYGPERVVDTPITEAGFTGIGVGAAYYGLRPVIEFMTFNFSMQAIDHIINSAAKSNYMSSGQISVPIVFRGPNGAAAGVGAQHSQCYAAWFGACPGLKVLTPYSSEDARGLLKAAIRDPDPVVFLENELLYGESFPVSAEVLDSSFCLPIGKAKIEREGKDVTITAFSKMVGYALQAAD...

XP_057804872.1
MLGVLRRTVACQGNHAWGLEQGLRVIASRTLSSSAKETMTVRDALNSALDEEMSADPKVFVMGEEVGEYQGAYKITKGLLDKYGPERVVDTPITEAGFTGIGVGAAYYGLRPVIEFMTFNFSMQAIDHIINSAAKSNYMSSGQISVPIVFRGPNGAAAGVGAQHSQCYAAWFGACPGLKVLTPYSSEDARGLLKAAIRDPDPVVFLENELLYGESFPVSAEVLDSSFCLPIGKAKIEREGKDVTITAFSKMVGYALQAAD...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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