Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G003453`

染色体: Chr04 坐标: 51010562-51015769 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G003453`
名称	SmilChr04G003453
描述	cell division control protein 6 homolog B-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	51010562 - 51015769 / `+`

ID 对照

NCBI Gene ID	`LOC131020347`
GeneID	`131020347`
locus_tag	`-`
NCBI Name	`LOC131020347`
原始查询	`SmilChr04G003453`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	cell division control protein 6 homolog B-like
产物	cell division control protein 6 homolog B-like
Arabidopsis	`AT1G07270` (AT1G07270) Cell division control, Cdc6 [Source:NCBI gene (formerly Entrezgene);Acc:837238] identity=59.3; qcov=0.956; evalue=0; confidence=high
Rice	`Os01g0856000` (OsCDC6) - identity=58.1; qcov=0.87; evalue=0; confidence=high
GO	GO:0003688 (DNA replication origin binding); GO:0005634 (nucleus); GO:0006270 (DNA replication initiation); GO:0016887 (ATP hydrolysis activity); GO:0033314 (mitotic DNA replication checkpoint signaling); GO:0051301 (cell division)
KEGG	-
Pfam	PF09079 (WHD_Cdc6); PF13401 (AAA_22); PF17872 (AAA_lid_10); PF22606 (Cdc6-ORC-like_ATPase_lid)
InterPro	-
eggNOG	-
NR	GeneID:131020347

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Nucleus	细胞核	1.00000	`XP_057805085.1`
2	Chromosome	染色体	1.00000	`XP_057805085.1`
3	Nucleoplasm	核质	0.40000	`XP_057805085.1`
4	Centromere	着丝粒	0.00000	`XP_057805085.1`
5	Chromatin	染色质	0.00000	`XP_057805085.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:51010761`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B53,B78,B79
`Chr4:51011456`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B91
`Chr4:51012367`	`G`	`A`	EMS_canonical_SNV	CDS_variant	5	A2,B31,C2,C42,C56
`Chr4:51013266`	`C`	`CTA`	2bp_insertion	frameshift_variant	53	A1,A11,A16,A20,A5,B100,B11,B117,B124,B125,B128,B134,B135,B140,B15,B22,B28,B29,B30,B35,B37,B39,B40,B42,B46,B52,B53,B55,B58,B6,B61,B68,B7,B70,B73,B78,B82,B94,B96,B98,C24,C3,C33,C40,C56,C64,C67,C70,C71,C77,C79,C80,C81
`Chr4:51013274`	`AT`	`A`	1bp_deletion	frameshift_variant	26	A1,A11,A16,A20,A5,B100,B140,B15,B22,B28,B35,B39,B46,B53,B6,B70,B82,B94,C16,C24,C3,C33,C40,C56,C77,C80
`Chr4:51014206`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B91

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057805085.1

500 aa

250

500

AAA_22

Cdc6-ORC-like_ATPase_lid

AAA_lid_10

WHD_Cdc6

PF13401 AAA_22 139-255 aa PF22606 Cdc6-ORC-like_ATPase_lid 296-350 aa PF17872 AAA_lid_10 318-349 aa PF09079 WHD_Cdc6 399-488 aa

XP_057805086.1

499 aa

250

499

AAA_22

Cdc6-ORC-like_ATPase_lid

AAA_lid_10

WHD_Cdc6

PF13401 AAA_22 138-254 aa PF22606 Cdc6-ORC-like_ATPase_lid 295-349 aa PF17872 AAA_lid_10 317-348 aa PF09079 WHD_Cdc6 398-487 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057805085.1`	Pfam	`PF13401`	AAA_22	Domain	139	255	1.1e-11	45.8	AAA domain
`XP_057805085.1`	Pfam	`PF22606`	Cdc6-ORC-like_ATPase_lid	Domain	296	350	5.1e-11	43.0	Cdc6/ORC-like, ATPase lid domain
`XP_057805085.1`	Pfam	`PF17872`	AAA_lid_10	Domain	318	349	8.8e-06	26.5	AAA lid domain
`XP_057805085.1`	Pfam	`PF09079`	WHD_Cdc6	Domain	399	488	6.9e-23	81.2	CDC6, C terminal winged helix domain
`XP_057805086.1`	Pfam	`PF13401`	AAA_22	Domain	138	254	1.1e-11	45.8	AAA domain
`XP_057805086.1`	Pfam	`PF22606`	Cdc6-ORC-like_ATPase_lid	Domain	295	349	5.1e-11	43.0	Cdc6/ORC-like, ATPase lid domain
`XP_057805086.1`	Pfam	`PF17872`	AAA_lid_10	Domain	317	348	7.9e-06	26.7	AAA lid domain
`XP_057805086.1`	Pfam	`PF09079`	WHD_Cdc6	Domain	398	487	5.7e-23	81.4	CDC6, C terminal winged helix domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057949102.1
CTCAGCCCCAACAACCTCACTCTCAATTTCTTCAACCTTTTTTCCATTTATACAGCTTCCGGCAGCAATCCCAAAACAGATATGCCGGCCTTCGCAGCTCGCCGTCAATCACTGTCGTCAGATCCGACCTATGAGACCAGAGTTGCCATTACACCTAGGAAAAGCCGTCTGAGATCCGATTCGGATGCTGCAATCGGATCGCCGCTGCGTAAATCTCCTCGTTTGTGCAAAGAAGGCGGCCCTAATAGTTCCCCGAAGAT...

XM_057949103.1
TCAGCCCCAACAACCTCACTCTCAATTTCTTCAACCTTTTTTCCATTTATACAGCTTCCGGCAGCAATCCCAAAACAGATATGCCGGCCTTCGCAGCTCGCCGTCAATCACTGTCGTCAGATCCGACCTATGAGACCAGAGTTGCCATTACACCTAGGAAAAGCCGTCTGAGATCCGATTCGGATGCTGCAATCGGATCGCCGCTGCGTAAATCTCCTCGTTTGTGCAAAGAAGGCGGCCCTAATAGTTCCCCGAAGATT...

CDS

2 records

下载 CDS FASTA

LOC131020347
ATGCCGGCCTTCGCAGCTCGCCGTCAATCACTGTCGTCAGATCCGACCTATGAGACCAGAGTTGCCATTACACCTAGGAAAAGCCGTCTGAGATCCGATTCGGATGCTGCAATCGGATCGCCGCTGCGTAAATCTCCTCGTTTGTGCAAAGAAGGCGGCCCTAATAGTTCCCCGAAGATTGATGTGATCCGAAAATGCCTGAAATCATCATTGAATTTGAGTGGATCGCCTCAGGAAAAGCGATTATATGAGAATTTTGT...

Protein

2 records

下载 Protein FASTA

XP_057805085.1
MPAFAARRQSLSSDPTYETRVAITPRKSRLRSDSDAAIGSPLRKSPRLCKEGGPNSSPKIDVIRKCLKSSLNLSGSPQEKRLYENFVERQTWDPRAEETQLRAVNEALHVSTAPTNVVCRENEQNRILDFCKKCVKEEKAGSLYVCGCPGTGKTLSMKKVQVMLVDWANKEGVQPPDILSINCTSLANMSEIFSKILGQNHSGKNSSRSTSSLQQLHNLYSQQQPGMKMILVIADELDYLITKDRAVLHDLFMLTTMPFS...

XP_057805086.1
MPAFAARRQSLSSDPTYETRVAITPRKSRLRSDSDAAIGSPLRKSPRLCKEGGPNSSPKIDVIRKCLKSSLNLSGSPQEKRLYENFVERQTWDPREETQLRAVNEALHVSTAPTNVVCRENEQNRILDFCKKCVKEEKAGSLYVCGCPGTGKTLSMKKVQVMLVDWANKEGVQPPDILSINCTSLANMSEIFSKILGQNHSGKNSSRSTSSLQQLHNLYSQQQPGMKMILVIADELDYLITKDRAVLHDLFMLTTMPFSR...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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