Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G003523`

染色体: Chr04 坐标: 51604833-51607438 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G003523`
名称	SmilChr04G003523
描述	malate dehydrogenase, chloroplastic-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	51604833 - 51607438 / `+`

ID 对照

NCBI Gene ID	`LOC131020408`
GeneID	`131020408`
locus_tag	`-`
NCBI Name	`LOC131020408`
原始查询	`SmilChr04G003523`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	malate dehydrogenase, chloroplastic-like
产物	malate dehydrogenase%2C chloroplastic-like
Arabidopsis	`AT3G47520` (MDH) malate dehydrogenase [Source:NCBI gene (formerly Entrezgene);Acc:823906] identity=73.3; qcov=0.912; evalue=0; confidence=high
Rice	`Os08g0434300` (MDH) - identity=76; qcov=0.903; evalue=0; confidence=high
GO	GO:0005737 (cytoplasm); GO:0005739 (mitochondrion); GO:0006099 (tricarboxylic acid cycle); GO:0006108 (malate metabolic process); GO:0030060 (L-malate dehydrogenase (NAD+) activity)
KEGG	smil00020 (Citrate cycle (TCA cycle) - Salvia miltiorrhiza (redroot sage)); smil00270 (Cysteine and methionine metabolism - Salvia miltiorrhiza (redroot sage)); smil00566 (Sulfoquinovose metabolism - Salvia miltiorrhiza (redroot sage)); smil00620 (Pyruvate metabolism - Salvia miltiorrhiza (redroot sage)); smil00630 (Glyoxylate and dicarboxylate metabolism - Salvia miltiorrhiza (redroot sage)); smil00710 (Carbon fixation by Calvin cycle - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01200 (Carbon metabolism - Salvia miltiorrhiza (redroot sage))
Pfam	PF00056 (Ldh_1_N); PF02866 (Ldh_1_C)
InterPro	-
eggNOG	-
NR	GeneID:131020408

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Chloroplast	叶绿体	1.00000	`XP_057805168.1`
2	Chloroplast stroma	叶绿体基质	1.00000	`XP_057805168.1`
3	Nucleus	细胞核	0.00000	`XP_057805168.1`
4	Chromosome	染色体	0.00000	`XP_057805168.1`
5	Centromere	着丝粒	0.00000	`XP_057805168.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:51606009`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	B97
`Chr4:51606165`	`GA`	`G`	1bp_deletion	frameshift_variant	3	B50,B6,C63
`Chr4:51606165`	`GA`	`G`	1bp_deletion	CDS_variant	3	B50,B6,C63
`Chr4:51606397`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A15
`Chr4:51606536`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	C27,D10
`Chr4:51606823`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	B99
`Chr4:51606979`	`G`	`A`	EMS_canonical_SNV	CDS_variant	2	B78,B79

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057805168.1

415 aa

208

415

Ldh_1_N

Ldh_1_C

PF00056 Ldh_1_N 96-238 aa PF02866 Ldh_1_C 240-408 aa

XP_057805169.1

411 aa

206

411

Ldh_1_N

Ldh_1_C

PF00056 Ldh_1_N 92-234 aa PF02866 Ldh_1_C 236-404 aa

XP_057805170.1

411 aa

206

411

Ldh_1_N

Ldh_1_C

PF00056 Ldh_1_N 92-234 aa PF02866 Ldh_1_C 236-404 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057805168.1`	Pfam	`PF00056`	Ldh_1_N	Domain	96	238	6.4e-44	150.1	lactate/malate dehydrogenase, NAD binding domain
`XP_057805168.1`	Pfam	`PF02866`	Ldh_1_C	Domain	240	408	2.6e-39	135.7	lactate/malate dehydrogenase, alpha/beta C-terminal domain
`XP_057805169.1`	Pfam	`PF00056`	Ldh_1_N	Domain	92	234	6.3e-44	150.2	lactate/malate dehydrogenase, NAD binding domain
`XP_057805169.1`	Pfam	`PF02866`	Ldh_1_C	Domain	236	404	2.5e-39	135.8	lactate/malate dehydrogenase, alpha/beta C-terminal domain
`XP_057805170.1`	Pfam	`PF00056`	Ldh_1_N	Domain	92	234	6.3e-44	150.2	lactate/malate dehydrogenase, NAD binding domain
`XP_057805170.1`	Pfam	`PF02866`	Ldh_1_C	Domain	236	404	2.5e-39	135.8	lactate/malate dehydrogenase, alpha/beta C-terminal domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

3 records

下载 cDNA FASTA

XM_057949185.1
AGGATGATTAGGATCTCAGAATTGGATATATCATTATCAGTATATCTTAAATGATAAAGTTAGTTAGAATTCTTCTTCTATCTCTCTTGTTCAGTCACACTCACACGAAAACCTATCAGATTGAGTTCTTCATCACACTTCTTCAACGAGTTCCGATCGGAAGAGGTAATGGTTGCCGTGAATCCGTGACAGCGATGTATGTTGATTCCACTAAGGCCCGTCGGCGGAGAAACTGAGAACAAACCTCGCTCACACGGACT...

XM_057949187.1
TGGATATATCATTATCAGTATATCTTAAATGATAAAGTTAGTTAGAATTCTTCTTCTATCTCTCTTGTTCAGTCACACTCACACGAAAACCTATCAGATTGAGTTCTTCATCACACTTCTTCAACGAGTTCCGATCGGAAGAGGTAATGGTTGCCGTGAATCCGTGACAGCGATGTATGTTGATTCCACTAAGGCCCGTCGGCGGAGAAACTGAGAACAAACCTCGCTCACACGGACTCCAGTGTGTCTCTGTGTGTATG...

CDS

3 records

下载 CDS FASTA

LOC131020408
ATGTGTTGCAAGATGGCAGCAACATCAACCACCACCTTCTATATTGGATCGACTGCATCTGCTAGCCCCAAAAGAGGTCAGTCAAGAGCCGTCAGAATCAAGCCCAACTCAAAAAACTGCCTTAGGAGTTTCAGTGGCCTCAAAGCAAGTAACGCCGTGAACTGCGAATCAGAATCGTCGTTCTTAGGTGGTGAAAGCTGCGCAGCTCTTAACCGCTTATACAATGGAGTTGCCCCAAAACAGAGCCACAGATGTTACAG...

LOC131020408
ATGGCAGCAACATCAACCACCACCTTCTATATTGGATCGACTGCATCTGCTAGCCCCAAAAGAGGTCAGTCAAGAGCCGTCAGAATCAAGCCCAACTCAAAAAACTGCCTTAGGAGTTTCAGTGGCCTCAAAGCAAGTAACGCCGTGAACTGCGAATCAGAATCGTCGTTCTTAGGTGGTGAAAGCTGCGCAGCTCTTAACCGCTTATACAATGGAGTTGCCCCAAAACAGAGCCACAGATGTTACAGTTATGTCCAGCC...

Protein

3 records

下载 Protein FASTA

XP_057805168.1
MCCKMAATSTTTFYIGSTASASPKRGQSRAVRIKPNSKNCLRSFSGLKASNAVNCESESSFLGGESCAALNRLYNGVAPKQSHRCYSYVQPRASYKVAILGAVGGIGEPLALLIKMSPLVSTLNLYDIANVKGVAADLSHCNTPSRVADFTGASELADCLKGADVVVIPAGVLRKPGMTWDDLFNTNANIVKTLVEAVADNCPDAFIHIISNPVNSTVPIAAEILKQKGVYDPKKLFGVTTLDVVRANTFVAQKKKLNLI...

XP_057805169.1
MAATSTTTFYIGSTASASPKRGQSRAVRIKPNSKNCLRSFSGLKASNAVNCESESSFLGGESCAALNRLYNGVAPKQSHRCYSYVQPRASYKVAILGAVGGIGEPLALLIKMSPLVSTLNLYDIANVKGVAADLSHCNTPSRVADFTGASELADCLKGADVVVIPAGVLRKPGMTWDDLFNTNANIVKTLVEAVADNCPDAFIHIISNPVNSTVPIAAEILKQKGVYDPKKLFGVTTLDVVRANTFVAQKKKLNLIDVDV...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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