Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G003541`

染色体: Chr04 坐标: 51763679-51768482 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G003541`
名称	SmilChr04G003541
描述	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase-like
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	51763679 - 51768482 / `+`

ID 对照

NCBI Gene ID	`LOC131020425`
GeneID	`131020425`
locus_tag	`-`
NCBI Name	`LOC131020425`
原始查询	`SmilChr04G003541`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; KEGG smil; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase-like
产物	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase-like
Arabidopsis	`AT5G17920` (ATMS1) Cobalamin-independent synthase family protein [Source:NCBI gene (formerly Entrezgene);Acc:831660] identity=87; qcov=0.982; evalue=0; confidence=high
Rice	`Os12g0624000` - identity=87.8; qcov=0.983; evalue=0; confidence=high
GO	GO:0003871 (5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity); GO:0008270 (zinc ion binding); GO:0009086 (GO:0009086)
KEGG	smil00270 (Cysteine and methionine metabolism - Salvia miltiorrhiza (redroot sage)); smil00450 (Selenocompound metabolism - Salvia miltiorrhiza (redroot sage)); smil01100 (Metabolic pathways - Salvia miltiorrhiza (redroot sage)); smil01110 (Biosynthesis of secondary metabolites - Salvia miltiorrhiza (redroot sage)); smil01230 (Biosynthesis of amino acids - Salvia miltiorrhiza (redroot sage))
Pfam	PF01717 (Meth_synt_2); PF08267 (Meth_synt_1)
InterPro	-
eggNOG	-
NR	GeneID:131020425

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Cytoplasm	细胞质	1.00000	`XP_057805188.1`
2	Cytosol	细胞质基质	1.00000	`XP_057805188.1`
3	Nucleus	细胞核	0.00000	`XP_057805188.1`
4	Chromosome	染色体	0.00000	`XP_057805188.1`
5	Centromere	着丝粒	0.00000	`XP_057805188.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:51764855`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	D11
`Chr4:51765056`	`C`	`T`	EMS_canonical_SNV	CDS_variant	3	B104,B138,D11
`Chr4:51766281`	`C`	`T`	EMS_canonical_SNV	CDS_variant	1	A21
`Chr4:51766338`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr4:51767595`	`C`	`T`	EMS_canonical_SNV	CDS_variant	2	B41,B85
`Chr4:51767824`	`C`	`T`	EMS_canonical_SNV	CDS_variant	5	A11,A22,B89,C76,D8
`Chr4:51767914`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D10
`Chr4:51768000`	`C`	`T`	EMS_canonical_SNV	CDS_variant	4	A11,A22,B89,D8

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057805188.1

765 aa

382

765

Meth_synt_1

Meth_synt_2

PF08267 Meth_synt_1 3-316 aa PF01717 Meth_synt_2 432-755 aa

XP_057805190.1

664 aa

332

664

Meth_synt_1

Meth_synt_2

PF08267 Meth_synt_1 3-316 aa PF01717 Meth_synt_2 432-652 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057805188.1`	Pfam	`PF08267`	Meth_synt_1	Domain	3	316	3.7e-125	418.3	Cobalamin-independent synthase, N-terminal domain
`XP_057805188.1`	Pfam	`PF01717`	Meth_synt_2	Domain	432	755	1.7e-165	550.8	Cobalamin-independent synthase, Catalytic domain
`XP_057805190.1`	Pfam	`PF08267`	Meth_synt_1	Domain	3	316	3.9e-124	415.0	Cobalamin-independent synthase, N-terminal domain
`XP_057805190.1`	Pfam	`PF01717`	Meth_synt_2	Domain	432	652	2.5e-110	369.5	Cobalamin-independent synthase, Catalytic domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057949205.1
AGCCCGTTCGCCCGTCTCCTCAGCTCGCGTCTCGCTTCTCTCTCTCTACCAGAAACCGATATCTGTGTTACGCCGCTCCCTTCGCAAGGAAAAAATGGCATCCCATATTGTTGGATACCCCCGAATGGGCCCCAAGAGAGAGCTCAAATTTGCTCTGGAATCTTTCTGGGATGGCAAGAGTAGTGCCGAGGATTTGGAAAAGGTGGCAGCTGACCTCAGAGCATCCATTTGGAAGCAGATGTCTGATGTTGGGATCAAGT...

XM_057949207.1
TACTTCTTTTGCTTGCCGCTGCTGTCTCTGTTCATCTGTTGCGCTCATTCATCCATATCTAGCTCTTCAGCAATTTTGGTTTCATAATTGATTGTTTTGGAGTTTCTGTTTGATTCGCTTAGATCTATTCTAATCGCTGTTTTCCGACGTTGGTTGCTTGATCTGAAAAAATGGCATCCCATATTGTTGGATACCCCCGAATGGGCCCCAAGAGAGAGCTCAAATTTGCTCTGGAATCTTTCTGGGATGGCAAGAGTAGT...

CDS

2 records

下载 CDS FASTA

LOC131020425
ATGGCATCCCATATTGTTGGATACCCCCGAATGGGCCCCAAGAGAGAGCTCAAATTTGCTCTGGAATCTTTCTGGGATGGCAAGAGTAGTGCCGAGGATTTGGAAAAGGTGGCAGCTGACCTCAGAGCATCCATTTGGAAGCAGATGTCTGATGTTGGGATCAAGTACATTCCCAGCAACACATTCTCATACTATGATCAGGTGCTTGACACAACTGCGATGCTCGGTGCTGTTCCCCCAAGATACAACTGGACTGGTGG...

Protein

2 records

下载 Protein FASTA

XP_057805188.1
MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVAADLRASIWKQMSDVGIKYIPSNTFSYYDQVLDTTAMLGAVPPRYNWTGGEIGFSTFFSMARGNASVPAMEMTKWFDTNYHFIVPELGPDVKFSYASHKAVNEYKEAKALGVDTVPVLVGPVSYLLLSKPAKGVEKTFPLLSLLDKILPIYKEVIAELKAAGASWIQFDEPTLVKDLESHQLEAFTKAYADLQSSLSGVDVLIETYFADIPAAAFKILTSLSG...

XP_057805190.1
MASHIVGYPRMGPKRELKFALESFWDGKSSAEDLEKVAADLRASIWKQMSDVGIKYIPSNTFSYYDQVLDTTAMLGAVPPRYNWTGGEIGFSTFFSMARGNASVPAMEMTKWFDTNYHFIVPELGPDVKFSYASHKAVNEYKEAKALGVDTVPVLVGPVSYLLLSKPAKGVEKTFPLLSLLDKILPIYKEVIAELKAAGASWIQFDEPTLVKDLESHQLEAFTKAYADLQSSLSGVDVLIETYFADIPAAAFKILTSLSG...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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JBrowse

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