Gene Card 基因详情

支持统一新 ID、NCBI Gene ID、GeneID、locus_tag、Transcript ID、Protein ID，以及已人工核对的文献基因名查询。页面会先解析到丹参统一基因，再整合坐标、序列、注释、亚细胞定位、EMS 突变和下载入口。

当前解析结果

`SmilChr04G003557`

染色体: Chr04 坐标: 51953178-51959851 链方向: + 类型: protein_coding

基本信息

统一新 Gene ID	`SmilChr04G003557`
名称	SmilChr04G003557
描述	rhomboid-like protein 15
染色体 / SeqID	Chr04 / NC_080390.1
坐标与链方向	51953178 - 51959851 / `+`

ID 对照

NCBI Gene ID	`LOC131020441`
GeneID	`131020441`
locus_tag	`-`
NCBI Name	`LOC131020441`
原始查询	`SmilChr04G003557`

查看完整 ID 对照表

功能注释

来源	GFF basic annotation; NCBI GO GAF; Pfam-A/HMMER; Arabidopsis/Rice homolog
描述	rhomboid-like protein 15
产物	rhomboid-like protein 15
Arabidopsis	`AT3G58460` (RBL15) RHOMBOID-like protein 15 [Source:NCBI gene (formerly Entrezgene);Acc:825015] identity=65.5; qcov=1; evalue=0; confidence=high
Rice	`Os03g0651100` (OsRhmbd9) - identity=72.5; qcov=0.505; evalue=3.27e-111; confidence=medium
GO	GO:0000839 (Hrd1p ubiquitin ligase ERAD-L complex); GO:0004252 (serine-type endopeptidase activity); GO:0005789 (endoplasmic reticulum membrane); GO:0030433 (GO:0030433); GO:0030968 (endoplasmic reticulum unfolded protein response); GO:0051787 (misfolded protein binding); GO:1990381 (ubiquitin-specific protease binding)
KEGG	-
Pfam	PF00627 (UBA); PF01694 (Rhomboid); PF04511 (DER1); PF08551 (DUF1751)
InterPro	-
eggNOG	-
NR	GeneID:131020441

打开注释模块

亚细胞定位 Top 5

Rank	定位位置	中文	Score	Protein ID
1	Endoplasmic reticulum	内质网	0.80000	`XP_057805220.1`
2	Endoplasmic reticulum membrane	内质网膜	0.80000	`XP_057805220.1`
3	Golgi apparatus	高尔基体	0.80000	`XP_057805221.1`
4	Cis-golgi network	Cis-golgi network	0.20000	`XP_057805221.1`
5	Nucleus	细胞核	0.00000	`XP_057805220.1`

进入亚细胞定位查询

EMS 诱变突变

下表显示该基因在丹参 EMS 材料中的前 12 个候选突变；完整结果可进入 EMS 突变库继续筛选或下载。

位置	REF	ALT	类型	影响	携带材料数	材料
`Chr4:51954950`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B35,C14,C40
`Chr4:51956563`	`G`	`A`	EMS_canonical_SNV	CDS_variant	3	B35,C14,C40
`Chr4:51957394`	`G`	`A`	EMS_canonical_SNV	CDS_variant	1	D2

进入 EMS 突变库

预测功能结构域

结构域结果来自 Pfam-A HMM 数据库和 HMMER hmmscan；位置为对应蛋白序列上的氨基酸坐标。

XP_057805220.1

428 aa

214

428

DER1

DUF1751

Rhomboid

UBA

PF04511 DER1 22-209 aa PF08551 DUF1751 28-207 aa PF01694 Rhomboid 62-212 aa PF00627 UBA 371-405 aa

XP_057805221.1

410 aa

205

410

DER1

DUF1751

Rhomboid

UBA

PF04511 DER1 22-209 aa PF08551 DUF1751 28-207 aa PF01694 Rhomboid 62-212 aa PF00627 UBA 371-405 aa

Protein ID	来源	结构域编号	结构域名称	类型	起始 aa	终止 aa	E-value	Score	说明
`XP_057805220.1`	Pfam	`PF04511`	DER1	Domain	22	209	6.8e-09	36.7	Der1-like family
`XP_057805220.1`	Pfam	`PF08551`	DUF1751	Domain	28	207	1.2e-06	28.8	Eukaryotic integral membrane protein (DUF1751)
`XP_057805220.1`	Pfam	`PF01694`	Rhomboid	Domain	62	212	2.1e-25	90.3	Rhomboid domain
`XP_057805220.1`	Pfam	`PF00627`	UBA	Domain	371	405	1.1e-07	32.2	UBA/TS-N domain
`XP_057805221.1`	Pfam	`PF04511`	DER1	Domain	22	209	8.3e-09	36.4	Der1-like family
`XP_057805221.1`	Pfam	`PF08551`	DUF1751	Domain	28	207	1.1e-06	28.9	Eukaryotic integral membrane protein (DUF1751)
`XP_057805221.1`	Pfam	`PF01694`	Rhomboid	Domain	62	212	1.9e-25	90.4	Rhomboid domain
`XP_057805221.1`	Pfam	`PF00627`	UBA	Domain	371	405	1.1e-07	32.3	UBA/TS-N domain

cDNA / CDS / Protein 序列

下载基因组 DNA（仅基因区域）

每个公开基因均提供参考注释对应的转录本序列；蛋白编码基因另提供 CDS 和蛋白序列。非编码 RNA 不适用 CDS 或蛋白下载。真实 accession 的版本后缀予以保留。

cDNA

2 records

下载 cDNA FASTA

XM_057949238.1
AACCCGATATTTTTACCCATATGCAAATACCCGACCCGATCATTAACGAATAAAGAATGTTATGAGTTTCCAAATCAAAATCTGAAGTAACATAATAACATTAGCACTGAAAATTCGCGAAGATTTCGAAGCGAGATGAGACCGAACGTCGTCTCCGAGGCGGGACTGTCCACCAGAGTTAACCAATGGTGGGAAGCTATTCCGTTTCTCACATCAGTCATTGTTGTTATTTGTGGAGCCATATATTTGGTCTGTCTGTT...

XM_057949237.1
ATGCAAATACCCGACCCGATCATTAACGAATAAAGAATGTTATGAGTTTCCAAATCAAAATCTGAAGTAACATAATAACATTAGCACTGAAAATTCGCGAAGATTTCGAAGCGAGATGAGACCGAACGTCGTCTCCGAGGCGGGACTGTCCACCAGAGTTAACCAATGGTGGGAAGCTATTCCGTTTCTCACATCAGTCATTGTTGTTATTTGTGGAGCCATATATTTGGTCTGTCTGTTTGTTGGGTATGACTCCTTTG...

CDS

2 records

下载 CDS FASTA

LOC131020441
ATGAGACCGAACGTCGTCTCCGAGGCGGGACTGTCCACCAGAGTTAACCAATGGTGGGAAGCTATTCCGTTTCTCACATCAGTCATTGTTGTTATTTGTGGAGCCATATATTTGGTCTGTCTGTTTGTTGGGTATGACTCCTTTGTTGAAGTCTGTTTCTTGCCTTCAGCTGTCGTTTCCCATTTTCAAGTTTACAGGATTTTCACCTCTATTATATTCCATGGTTCTATGCTGCATGTTCTCTTCAATATGTTGGCATT...

Protein

2 records

下载 Protein FASTA

XP_057805220.1
MRPNVVSEAGLSTRVNQWWEAIPFLTSVIVVICGAIYLVCLFVGYDSFVEVCFLPSAVVSHFQVYRIFTSIIFHGSMLHVLFNMLALVPMGSELERIMGSIRLLYIIILLAISSAILHLVIVLLAAYNPISSYPALMDQCSIGFSGILFSMIVIETSLSGVQSRSFFGLFNVPAKWYVWILLVVFQLLMANVSLLGHLCGILSGYAYTFGLFNILIPGASFYSSIEESSLLSACVRRPKFILCTGSNVSGNIPTYTSQNT...

XP_057805221.1
MRPNVVSEAGLSTRVNQWWEAIPFLTSVIVVICGAIYLVCLFVGYDSFVEVCFLPSAVVSHFQVYRIFTSIIFHGSMLHVLFNMLALVPMGSELERIMGSIRLLYIIILLAISSAILHLVIVLLAAYNPISSYPALMDQCSIGFSGILFSMIVIETSLSGVQSRSFFGLFNVPAKWYVWILLVVFQLLMANVSLLGHLCGILSGYAYTFGLFNILIPGASFYSSIEESSLLSACVRRPKFILCTGSNVSGNIPTYTSQNT...

上下游序列下载

upstream/downstream 最大各 10000 bp。负链基因会自动反向互补，使最终 FASTA 为转录方向 5′→3′。

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